Single-cell laser emitting cytometry for label-free nucleolus fingerprinting by Fang, Guocheng, Qiao, Zhen, Huang, Luqi, Zhu, Hui, Xie, Jun, Zhou, Tian, Xiong, Zhongshu, Su, I-Hsin, Jin, Dayong, Chen, Yu-Cheng

“…This approach holds promise for nucleolus-guided cell screening and drug evaluation, advancing the study of diseases such as cancer and neurodegenerative disorders.…”
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Real‐time imaging of dynamic cell reprogramming with nanosensors by Wiraja, Christian, Yeo, David Chenloong, Tham, Khek-Chian, Chew, Sharon Wan Ting, Lim, Xinhong, Xu, Chenjie

“…Cellular reprogramming, the process by which somatic cells regain pluripotency, is relevant in many disease modeling, therapeutic, and drug discovery applications. …”
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Effects of hemodynamic shear stress on circulating tumor cells by How, Yunhan

“…They also exhibit elongated cell morphology, greater drug resistance and higher expression of MnSOD, as compared to normal 231-C3.…”
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Establishment and optimization of induced pluripotent stem cell technologies by Amir Morshedi

“…This finding has had tremendous impact on drug discovery and disease modeling and there is great hope for these cells to replenish body cells for therapy. …”
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Homology modeling and expression of recombinant NS5-RDRP based on the Indonesian local strain of dengue virus for anti-dengue drug development by Subroto, Toto, Firdaus, Ade Rizqi Ridwan, Kusumawardani, Shinta, Tohari, Taufik Ramdani, Nababan, Theresia Adventina, Pertiwi, Wulan, Fadhlillah, Muhammad, Kusuma, Sri Agung Fitri, Rukayadi, Yaya

“…The isolated NS5-RdRp gene from the local strain was then inserted into the pET28a(+) plasmid and transformed into E. coli BL21(DE3) as the host cell. Recombinant NS5-RdRp was predominantly found in the insoluble fraction with a molecular weight of 72 kDa. …”
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Mechanism of damnacanthal induced apoptosis in CEM-SS cell line by Gopalsamy, Banulata, Saiful Yazan, Latifah, Abdul Hamid, Hisyam

“…All rights reserved.…”
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Interfacial phenomena and biological recognition of mammalian cells on biomimetic materials by Chan, Vincent.

“…Our work has been mainly focused on the elucidation of bio-interfacial phenomena that are involved in cell therapeutics device and drug delivery systems. …”
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Conservation of red blood cell signalling in Plasmodium merozoite invasion by Yong, James Jia Ming

“…Red blood cells (RBC) possess essential signalling cascades that are involved in Plasmodium merozoite invasion. …”
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Modulating T-cell activation with antisense oligoucleotides targeting lymphocyte cytosolic protein 2 by Iyer, Vaishnavi Srinivasan, Boddul, Sanjaykumar V., Johnsson, Anna-Karin, Raposo, Bruno, Sharma, Ravi K., Shen, Yunbing, Kasza, Zsolt, Lim, Kah Wai, Chemin, Karine, Nilsson, Gunnar, Malmström, Vivianne, Phan, Anh Tuân, Wermeling, Fredrik

“…The lymphocyte cytosolic protein 2 (LCP2), also known as SLP-76, is essential for the development and activation of T cells. Despite the critical role of LCP2 in T-cell activation and the need for developing drugs that modify T-cell activation, no LCP2 inhibitors have been developed. …”
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Image classification of unlabeled malaria parasites in red blood cells by Zhang, Zheng

“…It is more challenging to design algorithms for unstained parasites as the differences between infected cells and uninfected cells are less obvious. However, this approach will allow observations of malaria parasite progression and provide statistics on how malaria parasites respond to different drug treatments over time.…”
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Enhanced expression of codon optimized interferon gamma in CHO cells by Yusufi, Faraaz N. K., Yang, Yuansheng, Lee, Dong-Yup, Chung, Bevan Kai-Sheng, Mariati

“…The human interferon-gamma (IFN-γ) is a potential drug candidate for treating various diseases due to its immunomodulatory properties. …”
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Finite element modelling of nanoindentation based methods for mechanical properties of cells by Chen, Jinju, Lu, Guoxing

“…The viscoelastic properties of the living cells are for quantifying the biomechanical effects of drug treatment, diseases and aging. …”
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‘When I open it, I have to drink it all’: push and pull factors shaping domestic alcohol consumption during the COVID-19 pandemic UK Spring 2020 lockdown by Conroy, Dom, Nicholls, Emily

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Spatially controlled molecular encapsulation in natural pine pollen microcapsules by Prabhakar, Arun Kumar, Potroz, Michael G., Park, Soohyun, Miyako, Eijiro, Cho, Nam-Joon

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Amorphous ternary nanoparticle complex of curcumin-chitosan-hypromellose exhibiting built-in solubility enhancement and physical stability of curcumin by Wong, Jerome Jie Long, Lim, Li Ming, Tran, The-Thien, Wang, Danping, Cheow, Wean Sin, Hadinoto, Kunn

“…The results showed that the CUR-CHI-HPMC nanoplex exhibited superior (i) amorphous state stability after twelve-month storage, (ii) dissolution characteristics, and (iii) solubility enhancement in simulated gastrointestinal fluids, with minimal cytotoxicity towards human gastric epithelial cells.…”
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Chromosome integrity : a major determinant of mitotic cell death in cancer treatment by Lai, Soak Kuan

“…Mitotic cell death is a major cell death pathway that occurs in cancer cells which have been treated with chemotherapeutic drugs. …”
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Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition by Flower, Cameron Timothy

“…Using commonly prescribed TK inhibitors (TKIs), I show that TK genetic status generally predicts whether or not a cell line will show any response to genotype-matched TKI (GM-TKI), but is insufficient to predict drug tolerance, the ability of a cell line to sustain proliferation under drug. …”
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Self-propelled autonomous Mg/Pt janus micromotor interaction with human cells by Kong, Lei, Chia, Hui Ling, Guan, Jianguo, Pumera, Martin, Nur Farhanah Rosli

“…It has also been demonstrated that they have potential for drug delivery in mouse stomach. However, their biocompatibility and cytotoxicity to human cells have yet to be studied. …”
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Functionalized microwell laser sorting method for single-cell viable microbial detection by Wang, Y, Xue, Y, Hong, X, Wang, H, Zhou, C, Wang, W, Sheng, J, Liang, P, Li, H, Xu, Q, Wang, Y, Liu, K, Shang, L, Peng, H, Chen, F, Zhang, K, Yin, H, Wang, Y, Deng, F, Feng, S, Huang, WE, Li, B

“…Microbial detection at the single-cell level offers a novel approach for understanding intricacies of biological systems at the most fundamental level, influencing the advances in therapeutics, drug discoveries, and bioenergy. …”

Development of a protein nanoparticle platform for targeting EGFR expressing cancer cells by Buecheler, Jakob W., Howard, Christopher B., de Bakker, Christopher J., Goodall, Stephen, Jones, Martina L., Win, Thinzar, Peng, Tao, Tan, Cher Heng, Chopra, Akhil, Mahler, Stephen M., Lim, Sierin

“…The binding of the conjugated E2 particle to native EGFR on MDA MB 231 cells and recombinant EGFR was confirmed using flow cytometry and biolayer interferometry, respectively. …”
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