Biotin-streptavidin binding interactions of dielectric filled silicon bulk acoustic resonators for smart label-free biochemical sensor applications by Heidari, Amir, Yoon, Yong-Jin, Park, Woo-Tae, Su, Pei-Chen, Miao, Jianmin, Park, Mi Kyoung, Lin, Julius Tsai Ming

“…Sensor performance of a dielectric filled silicon bulk acoustic resonator type label-free biosensor is verified with biotin-streptavidin binding interactions as a model system. …”
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Biocementation of sand filled geotextile tubes by Yong, Hoi Zett

“…Nonetheless, the strength and durability of geotextile tubes that filled with sand or clay slurry still need to be improved. …”
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Binding modes of teixobactin to lipid ii : molecular dynamics study by Liu, Yang, Liu, Yaxin, Chan-Park, Mary Bee Eng, Mu, Yuguang

“…Teixobactin (TXB) is a newly discovered antibiotic targeting the bacterial cell wall precursor Lipid II (LII). In the present work, four binding modes of TXB on LII were identified by a contact-map based clustering method. …”
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Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics by Lukman, Suryani., Lane, David P., Verma, Chandra S.

“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
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The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

“…In silico analysis using RosettaLigand and GLIDE demonstrated a well-converged pose of SKA-346 in a binding pocket at the interface between the calmodulin N-lobe and the S45A helix in the S4-S5 linker of the KCa3.1 channel. …”
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Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore by Ivan, Fransiskus Xaverius, Zhou, Xinrui, Lau, Suk Hiang, Rashid, Shamima, Teo, Jasmine S. M., Lee, Hong Kai, Koay, Evelyn S., Chan, Kwai Peng, Leo, Yee Sin, Chen, Mark I. Cheng, Kwoh, Chee Keong, Chow, Vincent T.

“…Background: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular evolution and receptor-binding specificity. …”
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Cationic glycosylated block co-β-peptide acts on the cell wall of Gram-positive bacteria as anti-biofilm agents by Zhang, Kaixi, Raju, Cheerlavancha, Zhong, Wenbin, Pethe, Kevin, Gründling, Angelika, Chan-Park, Mary B.

“…Strategies to tackle antibiotic resistance as well as biofilms are urgently needed. Wall teichoic acid (WTA), a generic anionic glycopolymer present on the cell surface of many Gram-positive bacteria, has been proposed as a possible therapeutic target, but its druggability remains to be demonstrated. …”
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Methods for the Study of Galactofuranose in Mycobacteria by Taylor, Katherine I.

“…We evaluated strains with varying galactan structures and compared our data to previous characterization of the cell wall to assess the method’s utility. Finally, we characterized the kinetics of a mild electrophile, the squaric ester, and assessed its utility in selectively binding and modifying a key galactofuranosyl transferase involved in mycobacterial cell wall biosynthesis. …”
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Synthesis and application of peptidoglycan oligomers as metabolic labeling agents for bacteria by He, Jingxi

“…In the following part, mechanistic studies further supported the hypothesis of enzyme mediated metabolic labeling rather than non-specific binding to bacterial surface. The cell wall-deficient L-form strain of enterococcus showed a drastic reduction in PGO-rhodamine incorporation, and calorimetric studies further confirmed the strong binding between our PGOs and the penicillin-binding protein 1a (PBP1a). …”
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Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…</p> <br> <p>The findings of ‘STORY’ confirm that SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalisation. …”

Enzymatic preparation of diacylglycerols: lipase screening, immobilization, characterization and glycerolysis performance by Xie, Rui, Peng, Xianwu, Lee, Yee-Ying, Xie, Pengkai, Tan, Chin-Ping, Wang, Yong, Zhang, Zhen

“…Backgrounds: Glycerolysis, with its advantages of readily available raw materials, simple operation, and mild reaction conditions, is a primary method for producing diacylglycerol (DAG). …”

Structural features that affect β2 integrin expression and regulation of adhesion by Guan, Siyu

“…In contrast, integrins with the β2-G150D mutation have no binding activities. LFA-1 with the β2-G716A mutation is constitutively active to bind ICAM-1 and requires only one activating agents to bind to ICAM-3. …”
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Different modes of regulation govern miRNA expression levels in Drosophila melanogaster by Lim, Mandy Yu Theng

“…Loquacious (Loqs) is a dsRNA-binding protein that binds Dicer-1 to cleave pre-miRNAs into short duplexes. …”
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Construction and characterization of a Lactococcus lactis in-trans surface display system harboring murine glycosylated tyrosinase related protein-2 by Kalyanasundram, Jeevanathan

“…Subsequent mTRP-2-cA anchoring to the cell wall of L. lactis showed excitation of FITC conjugate on secondary antibody which signified successful binding of glycosylated TRP-2 on the surface of L. lactis.…”
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Anisotropic protein diffusion on nanosurface by Liu, Yang, Song, Xiaohan, Yang, Yanmei, Li, Yong-Qiang, Zhao, Mingwen, Mu, Yuguang, Li, Weifeng

“…On the MBP surface, HP35 migrates mainly along the zigzag direction but can also easily stride over the ridges and grooves along the armchair direction. Moreover, the mild binding strength between α-PC and HP35 does not cause distortion in the protein structure. …”
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Protective Capacity of the Human Anamnestic Antibody Response during Acute Dengue Virus Infection by Xu, Meihui, Züst, Roland, Toh, Ying Xiu, Pfaff, Jennifer M., Kahle, Kristen M., Davidson, Edgar, Doranz, Benjamin J., Velumani, Sumathy, Tukijan, Farhana, Wang, Cheng-I, Fink, Katja

“…Half of the world's population is exposed to the risk of dengue virus infection. …”
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Bifunctional diazirine reagent for covalent dyeing of Kevlar and inert polymer materials by Liu, Richard Y., Luo, Shao-Xiong Lennon, Hirst, Elizabeth S., Doona, Christopher J., Swager, Timothy M.

“…The reagent's structure features a trifluoromethyl diazirine group as a precursor to a carbene that binds the textile surface. On the reagent's other terminus, a benzyl bromide group acts as a site accessible for substitution reactions. …”
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Elucidating the mechanism of mRNA transport using novel imaging technologies by Stoychev, D

“…The MS2-MCP system is used to insert into mRNAs of interest special structures to which RNA-binding proteins, fused to a fluorescent protein such as GFP, can then bind. …”

Effects of condensed tannin fractions from Leucaena leucocephala (LAM.) De wit hybrid on methane mitigation, rumen fermentation and diversity of methanogens, protozoa and bacteria... by Mookiah, Saminathan

“…The b values representing the CT quantities needed to bind half of the maximum precipitable bovine serum albumin increased with decreasing MWs from fraction F1 to fraction F5, with values of 0.216, 0.295, 0.359, 0.425, and 0.460, respectively. …”
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Vypal2: a versatile peptide ligase for precision tailoring of proteins by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Lescar, Julien, Tam, James P., Liu, Chuan-Fa

“…The last two decades have seen an increasing demand for new protein-modification methods from the biotech industry and biomedical research communities. Owing to their mild aqueous reaction conditions, enzymatic methods based on the use of peptide ligases are particularly desirable. …”
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