The relationship between leisure time physical activity patterns, Alzheimer’s disease markers and cognition by James, S, Sudre, CH, Barnes, J, Cash, DM, Chiou, Y, Coath, W, Keshavan, A, Lu, K, Malone, I, Murray-Smith, H, Nicholas, JM, Orini, M, Parker, T, Almeida-Meza, P, Fox, NC, Richards, M, Schott, JM

“…There was little evidence that leisure time physical activity had direct effects on other brain health measures (all P > 0.05). However, leisure time physical activity patterns modified and attenuated the association between poorer cognitive functioning at age 70 and a range of Alzheimer’s disease-related neurodegenerative markers (Aβ status; hippocampal and whole-brain volume; cortical thickness in Alzheimer’s disease regions) (all P < 0.05). …”

21W.775 Writing about Nature and Environmental Issues, Spring 2006 by Lioi, Anthony

“…Students will keep a web log as a journal. Writings are drawn from the tradition of nature writing and from contemporary forms of the environmentalist essay. …”
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Synthesis of densely functionalized pyrroles from unprotected carbohydrates by Xia, Mengxin

“…The activity of pyrrole-based drugs is tuned with the type of substituents on the pyrrole core and on the substitution pattern on the core pyrrole ring. …”
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The influence of additives on the delivery of paclitaxel from bioresorbable PLGA films by Huang, Charlotte Liwen.

“…The study of the influences of additives on the drug delivery characteristics from PLGA thin films as a coating on angioplasty balloons was reported in this thesis. …”
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Financial forecasting using meta-cognitive fuzzy neural networks by Singh Akhand Pratap

“…Some potential ways to address the above issues could be usage of synthetic data through time-series models to train the model till the test date; usage of manual inferences drawn from the indicators to make judgements about the present day; usage of multiple machine learning models and combining the results from all; usage of dynamic feature selection mechanism to make improvements to the prediction; and usage of dynamic thresholds that are dependent on the market conditions. …”
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Collective synthesis of 4-Hydroxy-2-pyridone alkaloids and their antiproliferation activities by Ding, Feiqing, Leow, Min Li, Ma, Jimei, William, Ronny, Liao, Hongze, Liu, Xue-Wei

“…Hence, this approach could potentially contribute to the synthesis of bioactive small-molecule libraries as well as drug discovery.…”
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Viral content: a theory of vaccine hesitancy based on information encountering in the greater Manila area, Philippines by Sacramento, Simon Philip R., Sipin, Ian Dominic P.

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Transcriptional profiling and network-based gene annotations of human malaria parasite plasmodium falciparum by Hu, Guang An

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Discovery of stabilized functional mutants of human aquaporin 1 by Soh, Miao Yi

“…Aquaporins (AQPs) are essential water channel proteins found in the cell membranes of all forms of life. In this project, a random mutagenesis library for human aquaporin 1 (hAQP1) is generated and screened for functional mutants. …”
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Studies towards the synthesis of bioactive natural products and development of new synthetic methods by Khanizeman, Rabi’ah Nisha

“…It has been estimated that more than half of all approved drugs, from the period 1981 to 2014, are either natural products or their derivatives. …”
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Migration of magnetic microparticles through a liquid–liquid interface under an external magnetic field by Mondal, S, Abbasi, N, Tsai, SSH, Griffiths, IM

“…Liquid–liquid interfaces play a pivotal role in various microfluidic processes involving microparticles, including coating, dissolution, controlled release of polyelectrolytes or drugs, and self-assembly processes. In all of these cases, non-invasive techniques to manipulate the microparticle transport are essential. …”

Compressible hollow microlasers in organoids for high-throughput and real-time mechanical screening by Fang, Guocheng, Ho, Beatrice Xuan, Xu, Hongmei, Gong, Chaoyang, Qiao, Zhen, Liao, Yikai, Zhu, Song, Lu, Hongxu, Nie, Ningyuan, Zhou, Tian, Kim, Munho, Huang, Changjin, Soh, Boon Seng, Chen, Yu-Cheng

“…Here, we introduce biocompatible and compressible hollow microlasers that realize all-optical assessment of cellular stress within organoids. …”
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Practitioner, patient and public views on the acceptability of mobile stroke units in England and Wales: A mixed methods study by Moseley, L, McMeekin, P, Price, C, Shaw, L, Laws, A, Allen, M, Ford, GA, James, M, McCarthy, S, McClelland, G, Park, LJ, Pearn, K, Phillips, D, White, P, Wilson, D, Scott, J

“…Results: The study results, drawn from 25 respondents to the survey and 21 participants in qualitative workshops, found that almost all participants had positive affective attitudes to the concept of MSUs. …”

Self-propelled autonomous Mg/Pt janus micromotor interaction with human cells by Kong, Lei, Chia, Hui Ling, Guan, Jianguo, Pumera, Martin, Nur Farhanah Rosli

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Dearomatization of (hetero)arenes through photodriven interplay between polysulfide anions and formate by Tan, Eugene Yew Kun, Mat Lani, Amirah S, Sow, Wayne, Liu, Yuliang, Li, Haoyu, Chiba, Shunsuke

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Integrate Traditional Chinese Medicine (TCM) into cognitive behavioural therapy to treat postpartum depression in Chinese culture contexts. by Han, Shuyu.

“…As in Chinese cultures, it is believed that any kind of drug has certain degree of side effects. In the end, all different kinds of factors have lead to the fact that most women suffering from postpartum disorders or depression left unwell treated. …”
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Predicting rifampicin resistance in M. tuberculosis using machine learning informed by protein structural and chemical features by Lynch, C, Adlard, D, Fowler, P

“…We have trained a learning models with the aim of complementing genetics-based drug susceptibility testing.</p> <br> <p><strong>Methods:</strong> We built a Test+Train dataset comprising 219 susceptible mutations. …”

Sharing is caring? International Society for Pharmacoepidemiology review and recommendations for sharing programming code by Tazare, J, Wang, SV, Gini, R, Prieto Alhambra, D, Arlett, P, Morales Leaver, DR, Morton, C, Logie, J, Popovic, J, Donegan, K, Schneeweiss, S, Douglas, I, Schultze, A

“…<p><strong> Methods: </p></strong>We conducted a literature review identifying all studies published in Pharmacoepidemiology and Drug Safety (PDS) between 2017 and 2022. …”

Tumor-targeted nano-assemblies for energy-blocking cocktail therapy in cancer by Chen, Manling, Liu, Yidu, Li, Yang, Liu, Xue

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Revealing the biotoxicity of phosphorene oxide nanosheets based on the villin headpiece by Zhang, Wei, Gou, Yuanyuan, Cheng, Li, Dong, Kaiwei, Sheng, Yijie, Ye, Chao, Yang, Xianqing, Mu, Yuguang

“…Phosphorene, a novel member of the two-dimensional nanomaterial family, has demonstrated great potential in biomedical applications, such as photothermal therapy, drug delivery and antibacterial. However, phosphorene is unstable and easily oxidized in an aerobic environment. …”
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