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Bad Mexican : portrayal of corruption and the drug trade in Man on Fire, Traffic, and La Ley de Herodes.
Published 2011“…By victimizing the United States and demonizing Mexico, Hollywood films such as Traffic and Man on Fire create stereotypes of Mexicans based on the drug trade and corruption in Mexico so the United States can define its identity and become Mexico’s saviour. …”
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Final Year Project (FYP) -
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Homology modeling and expression of recombinant NS5-RDRP based on the Indonesian local strain of dengue virus for anti-dengue drug development
Published 2024“…As a result, the RdRp gene, which belongs to the non-structural protein 5 (NS5) of DENV, was successfully isolated and sequenced from DENV RNA samples. …”
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Transdermal Drug Delivery
Published 2016“…As each drugs have different molecular properties, operation parameters are varied accordingly. …”
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Final Year Project (FYP) -
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Boronic acid and nitrofuranyl derivatives as potential therapeutics
Published 2021“…‘Rule of 5’, there has been extensive research on lead-like compounds other than those in the realm of small molecule drug-likeness. …”
Thesis -
5
Towards Health Centered Drug Policy: An Analysis of Past and Developing Drug Policy
Published 2024“…Drug criminalization has disproportionately impacted communities of color and has insufficiently addressed substance use disorder and its associated risk of death through overdosing. …”
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Millifluidic synthesis of amorphous drug-polysaccharide nanoparticle complex with tunable size intended for supersaturating drug delivery applications
Published 2016“…The conventional bulk mixing method to prepare amorphous drug-polysaccharide nanoparticle complex (or drug nanoplex in short) has a major drawback in the lack of size control for the nanoplex produced, hence limiting its potential applications as a supersaturating drug delivery system for bioavailability enhancement of poorly soluble drugs. …”
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Journal Article -
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Nanosized silica particles for achiral drug separation
Published 2009“…It is widely recognized that the full potential of rapid chromatography can be realized with very small support particulates and tailor-made chiral stationary phase. …”
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Research Report -
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Drug-eluting scaffolds for bone and cartilage regeneration
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Journal Article -
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Enzyme-responsive nanoparticles for drug release and diagnostics
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Journal Article -
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1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity
Published 2020“…The emergence of multi- and extensively-drug resistant tubercular (MDR- and XDR-TB) strains of mycobacteria has limited the use of existing therapies, therefore new drugs are needed. …”
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Journal Article -
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Can we please have some honesty about drugs
Published 2018“…Finally, in section four, I will discuss contemporary research on drugs. In section five, I consider more objections to the arguments I have made and draw a final conclusion: that policy should be framed based on evidence.…”
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Final Year Project (FYP) -
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Liposomal carrier systems for encapsulation of drugs using bicellar mixtures
Published 2024“…This research aims to evaluate the physicochemical properties of bicelles, such as particle size, distribution, and encapsulation efficiency of drugs. The bicelles will be fabricated using the LUCA cycles (freeze-thaw-vortex cycles) by varying the q-ratio (0, 2, 5, 8, 10, and 20) and total lipid concentration (2mM, 5mM and 10mM). …”
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Final Year Project (FYP) -
17
18F-labelling of new chemotypes for drug discovery
Published 2016“…</p> <p><b>Chapter 4</b> investigates the <sup>18</sup>F-labelling of α,α-difluoro-α-aryloxyacetic acid, a class of substrate that can serve as a versatile intermediate which can undergo various decarboxylative functionalisation reactions to afford a wide range of novel <sup>18</sup>F labelled α fluorinated aryl ethers. Finally, Chapter 5 gives full experimental procedures and characterisation data for all compounds.…”
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Amplifying signals in the tumor microenvironment for drug development and diagnostics
Published 2024“…Leveraging advancements in high throughput screening and in deep learning, we contribute important tools for the effective design of conditional drugs that require the cleavage of a protease substrate to unleash drug cytotoxicity. …”
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Thesis -
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Investigating viral glycosylation pathways for drug and vaccine development
Published 2021“…</p> <p>The COVID-19 pandemic highlighted again the lack of broad-spectrum antivirals available to patients before thorough investigation of an emergent virus, such as its genome or target host receptor. Chapter 5 discusses the establishment of a medium-throughput drug screening platform against SARS-CoV-2. …”
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Mycobacterium tuberculosis drug resistance detection by pyrosequencing method
Published 2014“…The conventional way of detecting Mycobacterium tuberculosis and its resistance is by culture followed by phenotypic drug susceptibility testing. This laborious process usually takes 4 to 12 weeks due to the slow growing nature of the organism. …”
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Thesis