Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites by Kumar, Ammu Prasanna, Nguyen, Minh Nhan, Verma, Chandra, Lukman, Suryani

Get full text

A multiphysics model of photo-sensitive hydrogels in response to light-thermo-pH-salt coupled stimuli for biomedical applications by Chen, Xiao, Li, Hua, Lam, King-Yeung

Get full text

Gender-based multi-aspect sentiment detection using multilabel learning by Kumar, J. Ashok, Trueman, Tina Esther, Cambria, Erik

Get full text

Synthesis, biological evaluation, and stability studies of raloxifene mono- and bis-sulfamates as dual-targeting agents by Zaraei, S-O, Dohle, W, Anbar, HS, El-Gamal, R, Leblond, B, Foster, PA, Al-Tel, TH, Potter, BVL, El-Gamal, MI

“…All three possible sulfamate derivatives of the selective estrogen receptor modulator Raloxifene (bis-sulfamate 7 and two mono-sulfamates 8–9) were synthesized and evaluated as inhibitors of the clinical drug target steroid sulfatase (STS), both in cell-free and in cell-based assays, and also as estrogen receptor (ER) modulators. …”

Maritime clusters and their development interplay with ports by Zhang Wei

“…Two case examples, namely London and Hong Kong, are drawn from these clusters, showing a port’s contribution to maritime cluster development. …”
Get full text

Understanding mechanisms that maintain social anxiety disorder in autistic individuals through the Clark and Wells (1995) model and beyond: a systematic review by Lei, J, Mason, C, Russell, A, Hollocks, M, Leigh, E

“…Most studies used only self-report measures that may have inflated associations observed between social anxiety and mechanisms. All studies employed cross-sectional design, and no causality inferences could be drawn. …”

On the most energy-efficient input functions and the lowest input energy of passive linear circuits by Smunyahirun, Radit

“…Finally, generalization of the most energy-efficient functions and the lowest input energy for any order circuits is drawn. A dummy function is introduced which is essential for generalization. …”
Get full text
Get full text

An innovative design of household civil defence shelters by Khong, Zhi Cong.

“…Two aspects related to the hollow steel section filled with RCA design were further studied. The effects of RCA size and the presents of grout were studied with respect to their penetration resistance. …”
Get full text

Real‐time imaging of dynamic cell reprogramming with nanosensors by Wiraja, Christian, Yeo, David Chenloong, Tham, Khek-Chian, Chew, Sharon Wan Ting, Lim, Xinhong, Xu, Chenjie

Get full text

Membrane reconstitution of monoamine oxidase enzymes on supported lipid bilayers by Wang, Liulin, Kabir H. Biswas, Yoon, Bo Kyeong, Kawakami, Lisa M., Park, Soohyun, Groves, Jay T., Li, Lin, Huang, Wei, Cho, Nam-Joon

Get full text

Peptide asparaginyl ligases—renegade peptide bond makers by Tam, James P., Chan, Ning-Yu, Liew, Heng Tai, Tan, Shaun J., Chen, Yu

Get full text

Does everyone have the potential to achieve their ideal body weight? Lay theories about body weight and support for price discrimination policies by Li, Kevin Shaobo, Kokkoris, Michail D., Savani, Krishna

Get full text

Structure and subunit arrangement of Mycobacterial F1FO ATP synthase and novel features of the unique mycobacterial subunit δ by Kamariah, Neelagandan, Huber, Roland G., Nartey, Wilson, Bhushan, Shashi, Bond, Peter J., Grüber, Gerhard

“…The arrangement of δ relative to the N-termini of the catalytic α3β3-headpiece and its potential as a drug target are discussed.…”
Get full text

Tailoring the phase transition temperature to achieve high-performance cubic GeTe-based thermoelectrics by Ady Suwardi, Cao, Jing, Hu, Lei, Wei, Fengxia, Wu, Jing, Zhao, Yunshan, Lim, Su Hui, Yang, Lan, Tan, Xian Yi, Chien, Sheau Wei, Yin, Yan, Zhou, Wu-Xing, Wong, Nancy Lai Mun, Wang, Xizu, Lim, Suo Hon, Ni, Xiping, Li, Dengfeng, Yan, Qingyu, Zheng, Yun, Zhang, Gang, Xu, Jianwei

Get full text

Polymeric composites for powder-based additive manufacturing : materials and applications by Yuan, Shangqin, Shen, Fei, Chua, Chee Kai, Zhou, Kun

Get full text

1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity by Yang, Xuan, Wedajo, Wassihun, Yamada, Yoshiyuki, Dahlroth, Sue-Li, Neo, Jason Jun-Long, Dick, Thomas, Chui, Wai-Keung

Get full text

Real-time nanoplasmonic sensing of three-dimensional morphological changes in a supported lipid bilayer and antimicrobial testing applications by Yoon, Bo Kyeong, Park, Hyeonjin, Zhdanov, Vladimir P., Jackman, Joshua A., Cho, Nam-Joon

Get full text

Rapid construction of green nanopesticide delivery systems using sophorolipids as surfactants by flash nanoprecipitation by Ma, Enguang, Chen, Kai, Sun, Liang, Fu, Zhinan, Guo, Jiangtao, Liu, Jichang, Zhao, Jigang, Liu, Zhiyong, Lei, Zhigang, Li, Li, Hu, Xiao, Guo, Xuhong

Get full text

The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions by Ahmed, Syed Moiz, Ragunathan, Priya, Shin, Joon, Peter, Sabrina, Kleissle, Sabrina, Neuenschwander, Martin, Schäfer, Reinhold, Kries, Jens Peter V., Grüber, Gerhard, Dröge, Peter

Get full text

High expression of MnSOD promotes survival of circulating breast cancer cells and increases their resistance to doxorubicin by Fu, Afu, Ma, Shijun, Wei, Na, Tan, Blanche Xiao Xuan, Tan, Ern Yu, Luo, Kathy Qian

“…Specific siRNA-mediated MnSOD knockdown reversed all three phenotypes. Our findings therefore suggest that MnSOD plays an important integrative role in supporting cancer cell survival in circulation, metastasis, and doxorubicin resistance. …”
Get full text
Get full text