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Roughness-Controlled Self-Assembly of Mannitol/LB Agar Microparticles by Polymorphic Transformation for Pulmonary Drug Delivery
Published 2016“…The XRD and DSC results indicate that after immersing spray-dried mannitol/LB Agar microparticles in hexane, β-mannitol was completely transformed to α-mannitol in 1 h, and all the δ-mannitol was transformed to α form after 14 days. …”
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Journal Article -
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A hydrophilic polyimidazolium antibiotic targeting the membranes of Gram-negative bacteria
Published 2024“…The rise of MDR Gram-negative bacteria (GNB), especially those resistant to last-resort drugs such as carbapenems and colistin, is a global health risk and calls for increased efforts to discover new antimicrobial compounds. …”
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Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction
Published 2023“…Several patient-derived models have been established lately for the prediction of drug response. However, each of these models has its limitations that impede their clinical application. …”
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Journal Article -
46
Inhalable biomimetic nanomotor for pulmonary thrombus therapy
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Journal Article -
47
Early detection of reduced artemisinin susceptibility in plasmodium falciparum using novel phenotypic indicators
Published 2019“…The changes in eIF2α phosphorylation and DNA damage, appearing shortly after in vitro drug treatment, were successfully detected in malaria parasites, and correlated with artemisinin resistance, demonstrating their potentials in future clinical applications.…”
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Thesis -
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Spatially controlled molecular encapsulation in natural pine pollen microcapsules
Published 2020Get full text
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024“…These screens reveal antifungal drug targets, transporters responsible for drug uptake or efflux, as well as metabolic, signalling and trafficking pathways affecting antifungal susceptibility. …”
Thesis -
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo...
Published 2014“…In part II, my first project is the development of novel drug-loaded nanogels for pH sensitive drug release, which will be described in chapter 3. …”
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Thesis -
53
RES.10-001 Making Science and Engineering Pictures, Fall 2014
Published 2017Get full text
Learning Object -
54
Wind tunnel testing of a ducted-fan unmanned aerial vehicle
Published 2011“…The experiments were carried out in a closed-loop wind tunnel with the full-scale MAV at different configurations. Coefficients of lift, drag and pitching moment were first discussed in a simple configuration of varying pitch angle with different wing setups without the propeller motor. …”
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Final Year Project (FYP) -
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Wind tunnel design and fabrication for lift force investigation
Published 2020“…The object using is often a smaller model of the actual vehicle with all the dimensions scaled down appropriately to obtain the most accurate simulation results possible. …”
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Final Year Project (FYP) -
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SP.236 / ES.SP236 Exploring Pharmacology, Spring 2009
Published 2009“…From Abilify to Zyrtec, the world is full of interesting drugs. Such substances have cured diseases, started wars, and ended careers. …”
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Learning Object -
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Turbulent Flow over a Flexible Wall Undergoing a Streamwise Traveling Wavy Motion
Published 2005Get full text
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The treatment of malaria in pregnancy
Published 2001“…Studies are urgently needed to define the best therapeutic options and to develop new treatments, especially in Africa where drug resistance already compromises all strategies of control.…”
Book section -
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CETSA screening identifies known and novel thymidylate synthase inhibitors and slow intracellular activation of 5-fluorouracil
Published 2018“…The screen selected accurately for all the tested known drugs acting on TS. We also identified TS inhibitors with novel chemistry and marketed drugs that were not previously known to target TS, including the DNA methyltransferase inhibitor decitabine. …”
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Journal Article