Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals by Goh, Yun Shan, Rouers, Angeline, Fong, Siew-Wai, Zhuo, Nicole Ziyi, Hor, Pei Xiang, Loh, Chiew Yee, Huang, Yuling, Neo, Vanessa Kexin, Kam, Isaac Kai Jie, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Lee, Raphael Tze Chuen, Pada, Surinder, Sun, Louisa Jin, Ong, Desmond Luan Seng, Somani, Jyoti, Lee, Eng Sing, Maurer-Stroh, Sebastian, Wang, Cheng-I., Leo, Yee Sin, Ren, Ee Chee, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

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Progress in metafibers for sustainable radiative cooling and prospects of achieving thermally drawn metafibers by Qi, Miao, Wu, Tingting, Wang, Zhe, Wang, Zhixun, He, Bing, Zhang, Haozhe, Liu, Yanting, Xin, Jiwu, Zhou, Tianzhu, Zhou, Xuhui, Wei, Lei

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Plastic Instability in Co-Cr-Ni-Mo alloy wires drawn with different drawing practices by GVK, Sai Srikanth, Tan, Ming Jen, Liu, Zhenyun

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Homology modeling and expression of recombinant NS5-RDRP based on the Indonesian local strain of dengue virus for anti-dengue drug development by Subroto, Toto, Firdaus, Ade Rizqi Ridwan, Kusumawardani, Shinta, Tohari, Taufik Ramdani, Nababan, Theresia Adventina, Pertiwi, Wulan, Fadhlillah, Muhammad, Kusuma, Sri Agung Fitri, Rukayadi, Yaya

“…As a result, the RdRp gene, which belongs to the non-structural protein 5 (NS5) of DENV, was successfully isolated and sequenced from DENV RNA samples. …”
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Deep graph contrastive learning model for drug-drug interaction prediction by Jiang, Zhenyu, Gong, Zhi, Dai, Xiaopeng, Zhang, Hongyan, Ding, Pingjian, Shen, Cong

“…The existing methods often do not fully explore the relationship between the structural information and the functional information of drug molecules, resulting in low prediction accuracy for drug interactions, poor generalization, and other issues. …”
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Transdermal Drug Delivery by Ong, Yuhui

“…As each drugs have different molecular properties, operation parameters are varied accordingly. …”
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Towards Health Centered Drug Policy: An Analysis of Past and Developing Drug Policy by Lewis, Benjamin B.

“…Drug criminalization has disproportionately impacted communities of color and has insufficiently addressed substance use disorder and its associated risk of death through overdosing. …”
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Article 28 - Drug abuse by Sloth-Nielsen, R

Search for Heavy Narrow Dilepton Resonances in Pp Collisions at √s = 7 TeV and √s = 8 TeV by Apyan, Aram, Bendavid, Joshua L., Busza, Wit, Butz, Erik M., Cali, Ivan Amos, Chan, M., Gomez-Ceballos, Guillelmo, Goncharov, Maxim, Kim, Y., Klute, Markus, Krajczar, Krisztian F., Ma, Teng, Nahn, Steven, Paus, Christoph M. E., Ralph, Duncan Kelley, Rudolph, Matthew Scott, Stephans, George S. F., Sung, Kevin Kai Hong, Velicanu, Dragos Alexandru, Wenger, Edward Allen, Wyslouch, Boleslaw, Yilmaz, Yetkin, Yoon, A. S., Zanetti, Marco, Bauer, Gerry P, Dutta, Valentina, Levin, Andrew Michael, Roland, Christof E, Stoeckli, Fabian, Luckey Jr, P David, Roland, Gunther M, Sumorok, Konstanty C, Wolf, Roger, Yang, Mingming, Wyslouch, Victoria

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Liposomal encapsulation of pro-NO donor drug by Koh, Cheryl Jie Yan

“…In-vitro release study conducted using Phosphate buffered saline solution found that the drug was not fully encapsulated in the core of the liposomes, resulting in complete release of nitric oxide within a day. …”
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Millifluidic synthesis of amorphous drug-polysaccharide nanoparticle complex with tunable size intended for supersaturating drug delivery applications by Tran, The-Thien, Nguyen, Minh-Hiep, Tan, Yong Zen, Chew, Jia Wei, Khan, Saif A., Hadinoto, Kunn

“…The conventional bulk mixing method to prepare amorphous drug-polysaccharide nanoparticle complex (or drug nanoplex in short) has a major drawback in the lack of size control for the nanoplex produced, hence limiting its potential applications as a supersaturating drug delivery system for bioavailability enhancement of poorly soluble drugs. …”
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Assessing the permeability of supersaturating drug delivery system of amorphous drug-polyelectrolyte/protein nanoplexes in Caco-2 cell monolayer by Tran, The-Thien, Cheow, Wean Sin, Chua, Angeline, Yang, Guang, Poenar, Daniel Puiu, Hadinoto, Kunn

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Collection and analysis on data from Drugs.com by Aw, Teng Teng

“…In this report, Scrapy, is a web scraper, which will be used to extract data from Drugs.com. Scrapy is a framework, done in Python and the outputs will be saved in JSON files. …”
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Drug-eluting scaffolds for bone and cartilage regeneration by Lee, Wei Li, Loo, Say Chye Joachim, Huang, Charlotte L.

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Evaluation of drug reproductive toxicity and the underlying mechanisms by Wu, Sixian, Shang, Lijun, Xu, Wenming

Enzyme-responsive nanoparticles for drug release and diagnostics by Rica, Roberta de la, Aili, Daniel, Stevens, Molly M.

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1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity by Yang, Xuan, Wedajo, Wassihun, Yamada, Yoshiyuki, Dahlroth, Sue-Li, Neo, Jason Jun-Long, Dick, Thomas, Chui, Wai-Keung

“…The emergence of multi- and extensively-drug resistant tubercular (MDR- and XDR-TB) strains of mycobacteria has limited the use of existing therapies, therefore new drugs are needed. …”
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Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…</p> <p>The COVID-19 pandemic highlighted again the lack of broad-spectrum antivirals available to patients before thorough investigation of an emergent virus, such as its genome or target host receptor. Chapter 5 discusses the establishment of a medium-throughput drug screening platform against SARS-CoV-2. …”

18F-labelling of new chemotypes for drug discovery by Khotavivattana, T

“…<b>Chapter 2</b> describes a novel silver-mediated ¹⁸F-labelling of Ar-SCF3, Ar OCF3 and Ar-OCF2H, including [¹⁸F]Riluzole, the ¹⁸F labelled version of a drug for treatment of amyotrophic lateral sclerosis (ALS). …”

Mycobacterium tuberculosis drug resistance detection by pyrosequencing method by Goh, Mei Ling

“…The conventional way of detecting Mycobacterium tuberculosis and its resistance is by culture followed by phenotypic drug susceptibility testing. This laborious process usually takes 4 to 12 weeks due to the slow growing nature of the organism. …”
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