Deep graph contrastive learning model for drug-drug interaction prediction by Jiang, Zhenyu, Gong, Zhi, Dai, Xiaopeng, Zhang, Hongyan, Ding, Pingjian, Shen, Cong

“…The existing methods often do not fully explore the relationship between the structural information and the functional information of drug molecules, resulting in low prediction accuracy for drug interactions, poor generalization, and other issues. …”
Get full text

Liposomal encapsulation of pro-NO donor drug by Koh, Cheryl Jie Yan

“…In-vitro release study conducted using Phosphate buffered saline solution found that the drug was not fully encapsulated in the core of the liposomes, resulting in complete release of nitric oxide within a day. …”
Get full text

Collection and analysis on data from Drugs.com by Aw, Teng Teng

“…In this report, Scrapy, is a web scraper, which will be used to extract data from Drugs.com. Scrapy is a framework, done in Python and the outputs will be saved in JSON files. …”
Get full text

Mechanistic action of weak acid drugs on biofilms by Kundukad, Binu, Schussman, Megan, Yang, Kaiyuan, Seviour, Thomas, Yang, Liang, Rice, Scott A., Kjelleberg, Staffan, Doyle, Patrick S.

Get full text
Get full text

18F-labelling of new chemotypes for drug discovery by Khotavivattana, T

“…<b>Chapter 2</b> describes a novel silver-mediated ¹⁸F-labelling of Ar-SCF3, Ar OCF3 and Ar-OCF2H, including [¹⁸F]Riluzole, the ¹⁸F labelled version of a drug for treatment of amyotrophic lateral sclerosis (ALS). …”

Development of biomimetic 3D cancer platform for drug testing by Ker, Sia Fong

Get full text

Dynamic drug combination methods for suppressing bacterial antibiotics resistance adaptation by Bhone, Myint Kyaw

“…It is resistant to many drugs and the glycopeptide vancomycin is the only available antibiotic that is active against MRSA infections. …”
Get full text

Characterizing the conformational landscape of MDM2-binding p53 peptides using molecular dynamics simulations by Yadahalli, Shilpa, Li, Jianguo, Lane, David P., Gosavi, Shachi, Verma, Chandra Shekhar

Get full text
Get full text

A concise review of gold nanoparticles-based photo-responsive liposomes for controlled drug delivery by Mathiyazhakan, Malathi, Wiraja, Christian, Xu, Chenjie

Get full text
Get full text

Local release of rapamycin by microparticles delays islet rejection within the anterior chamber of the eye by Fan, Yanliang, Zheng, Xiaofeng, Berggren, Per-Olof, Loo, Joachim Say Chye, Yusuf Ali

Get full text
Get full text

Emergence of spatio-temporal variations in chemotherapeutic drug efficacy : in-vitro and in-silico 3D tumour spheroid studies by Sheraton, Muniraj Vivek, Chiew, Geraldine Giap Ying, Melnikov, Valentin, Tan, E. Y., Luo, K. Q., Verma, N., Sloot, Peter M. A.

Get full text

Artemisinin resistance in the malaria parasite, Plasmodium falciparum, originates from its initial transcriptional response by Zhu, Lei, van der Pluijm, Rob W., Kucharski, Michal, Nayak, Sourav, Tripathi, Jaishree, White, Nicholas J., Day, Nicholas P. J., Faiz, Abul, Phyo, Aung Pyae, Amaratunga, Chanaki, Lek, Dysoley, Ashley, Elizabeth A., Nosten, François, Smithuis, Frank, Ginsburg, Hagai, von Seidlein, Lorenz, Lin, Khin, Imwong, Mallika, Chotivanich, Kesinee, Mayxay, Mayfong, Dhorda, Mehul, Nguyen, Hoang Chau, Nguyen, Thuy Nhien Thanh, Miotto, Olivo, Newton, Paul N., Jittamala, Podjanee, Tripura, Rupam, Pukrittayakamee, Sasithon, Peto, Thomas J., Hien, Tran Tinh, Dondorp, Arjen M., Bozdech, Zbynek

Get full text

Investigating graph neural networks and classical feature-extraction techniques in activity-cliff and molecular property prediction by Dablander, MF

“…It is one of the key research areas in molecular machine learning and computational drug discovery. Recently, message-passing graph neural networks (GNNs) have emerged as a novel method to learn differentiable features directly from molecular graphs. …”

AI is a viable alternative to high throughput screening: a 318-target study by Wallach, Izhar, Bernard, Denzil, Nguyen, Kong, Ho, Gregory, Morrison, Adrian, Stecula, Adrian, Rosnik, Andreana, O’Sullivan, Ann Marie, Davtyan, Aram, Samudio, Ben, Thomas, Bill, Worley, Brad, Butler, Brittany, Laggner, Christian, Thayer, Desiree, Moharreri, Ehsan, Friedland, Greg, Truong, Ha, van den Bedem, Henry, Ng, Ho Leung, Stafford, Kate, Sarangapani, Krishna, Giesler, Kyle, Ngo, Lien, Mysinger, Michael, Ahmed, Mostafa, Anthis, Nicholas J., Henriksen, Niel, Gniewek, Pawel, Eckert, Sam, de Oliveira, Saulo, Suterwala, Shabbir, PrasadPrasad, Srimukh Veccham Krishna, Shek, Stefani, Contreras, Stephanie, Hare, Stephanie, Palazzo, Teresa, O’Brien, Terrence E., Van Grack, Tessa, Williams, Tiffany, Chern, Ting-Rong, Kenyon, Victor, Lee, Andreia H., Cann, Andrew B., Bergman, Bastiaan, Anderson, Brandon M., Cox, Bryan D., Warrington, Jeffrey M., Sorenson, Jon M., Goldenberg, Joshua M., Young, Matthew A., DeHaan, Nicholas, Pemberton, Ryan P., Schroedl, Stefan, Abramyan, Tigran M., Gupta, Tushita, Mysore, Venkatesh, Presser, Adam G., Ferrando, Adolfo A., Andricopulo, Adriano D., Ghosh, Agnidipta, Ayachi, Aicha Gharbi, Mushtaq, Aisha, Shaqra, Ala M., Toh, Alan Kie Leong, Smrcka, Alan V., Ciccia, Alberto, de Oliveira, Aldo Sena, Sverzhinsky, Aleksandr, de Sousa, Alessandra Mara, Agoulnik, Alexander I., Kushnir, Alexander, Freiberg, Alexander N., Statsyuk, Alexander V., Gingras, Alexandre R., Degterev, Alexei, Tomilov, Alexey, Vrielink, Alice, Garaeva, Alisa A., Bryant-Friedrich, Amanda, Caflisch, Amedeo, Patel, Amit K., Rangarajan, Amith Vikram, Matheeussen, An, Battistoni, Andrea, Caporali, Andrea, Chini, Andrea, Ilari, Andrea, Mattevi, Andrea, Foote, Andrea Talbot, Trabocchi, Andrea, Stahl, Andreas, Herr, Andrew B., Berti, Andrew, Freywald, Andrew, Reidenbach, Andrew G., Lam, Andrew, Cuddihy, Andrew R., White, Andrew, Taglialatela, Angelo

Get full text

Cloud Spark Cluster to analyse English prescription big data for NHS intelligence by Fernando, Sandra, Sowinski-Mydlarz, Viktor, Virdee, Bal Singh

“…Even though Spark is a complete in-memory framework, although limited with its big data platforms facilities compared to Hadoop, Spark analytics engine with Ha-doop distributed file system gives better throughput than Hadoop alone. …”
Get full text

Overcoming endurance issue : UAV-enabled communications with proactive caching by Xu, Xiaoli, Zeng, Yong, Guan, Yong Liang, Zhang, Rui

“…Specifically, we focus on content-centric communication systems, where a UAV is dispatched to serve a group of ground nodes (GNs) with random and asynchronous requests for files drawn from a given set. With the proposed scheme, at the beginning of each operation period, the UAV pro-actively transmits the files to a subset of selected GNs that cooperatively cache all the files. …”
Get full text
Get full text

Optimization of Lithium Iron Phosphate Battery Charging and Performance by Misic, Aleksandar

“…The methods for running experiments are described in Section 4. Section 5.1 gives the results for single cell experiments while Section 5.2 gives results for the battery pack. …”
Get full text

Sawmill: From Logs to Causal Diagnosis of Large Systems by Markakis, Markos, Chen, An Bo, Youngmann, Brit, Gao, Trinity, Zhang, Ziyu, Shahout, Rana, Chen, Peter Baile, Liu, Chunwei, Sabek, Ibrahim, Cafarella, Michael

Get full text

Design and development of bio-medical devices using rapid prototyping techniques by Phua, Kenneth Khiang Song.

“…This gives rise to controlled-release drug delivery devices (DDD). …”
Get full text

21W.775 Writing about Nature and Environmental Issues, Spring 2006 by Lioi, Anthony

“…Students will keep a web log as a journal. Writings are drawn from the tradition of nature writing and from contemporary forms of the environmentalist essay. …”
Get full text