Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate by Harlan, John E., Hajduk, Philip J., Fesik, Stephen W., Yoon, Ho Sup

“…Here we report that PH domains bind to phosphatidylinositol-4,5-bisphosphate and show that the lipid-binding site is located at the lip of the β-barrel. …”
Get full text
Get full text

Mind the grind by Chong, Joo Xuan, Foo, Elizabeth Wei Zhi, Tan, Natasha Jing Hui, Teng, Yuxiu

“…Paid solutions were also used to increase the reach of various key content pieces. Mind the Grind exceeded all of its impact objectives, recording improvements in attitudes (136.33%), perception of social normality (117.47%), perceived behavioural control (117.05%), actual behaviour (168.72%), and future behavioural intention (255.5%) regarding mindfulness meditation. …”
Get full text

The mechanics of dry surface grinding by Marshall, Earle Robert, 1919-

Get full text

Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein by Zhang, Si Min, Liao, Ying, Neo, Tuan Ling, Lu, Yanning, Liu, Ding Xiang, Vahlne, Anders, Tam, James Pingkwan

“…Peptide array scanning of overlapping peptides covering the entire length of S protein identified 34 putative self-binding peptides of six clusters, five of which contained octapeptide core consensus sequences. …”
Get full text

Nanobiolubricant grinding: a comprehensive review by Song, Yu-Xiang, Li, Chang-He, Zhou, Zong-Ming, Liu, Bo, Sharma, Shubham, Dambatta, Yusuf Suleiman, Zhang, Yan-Bin, Yang, Min, Gao, Teng, Liu, Ming-Zheng, Cui, Xin, Wang, Xiao-Ming, Xu, Wen-Hao, Li, Run-Ze, Wang, Da-Zhong

“…Secondly, the excellent grinding performance of the NEBL is clarified by its distinctive film formation, heat transfer, and multiple-field mobilization capacity. …”
Get full text

The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
Get full text

The ties that bind: on affective ties, power, nationalism, and competition over the global distribution of feeling by Hall, T, James, P

Regulation of mRNA abundance by polypyrimidine tract-binding protein-controlled alternate 5′ splice site choice by Hamid, Fursham M., Makeyev, Eugene V.

“…Here we report that polypyrimidine tract-binding protein 1 (Ptbp1/PTB/hnRNP-I) controls alternate 5′ and 3′ splice site (5′ss and 3′ss) usage in a large set of mammalian transcripts. …”
Get full text
Get full text

Multiscale topological indices for the quantitative prediction of SARS CoV-2 binding affinity change upon mutations by Bi, Jialin, Wee, JunJie, Liu, Xiang, Qu, Cunquan, Wang, Guanghui, Xia, Kelin

“…In this study, we provide insights into interactions between the SARS-CoV-2 S-protein and ACE2, and propose topological indices to quantitatively characterize the impact of mutations on binding affinity changes (ΔΔG). …”
Get full text

Predictive Modelling and Analysis of Process Parameters on Material Removal Characteristics in Abrasive Belt Grinding Process by Pandiyan, Vigneashwara, Caesarendra, Wahyu, Tjahjowidodo, Tegoeh, Praveen, Gunasekaran

Get full text
Get full text

Unveiling the chirality of the quantum anomalous Hall effect by Chen, Hongyu, Jin, Yuanjun, Mohammad Yahyavi, Belopolski, Ilya, Shao, Sen, Hou, Tao, Wang, Naizhou, Hsu, Chia-Hsiu, Zhao, Yilin, Yang, Bo, Ma, Qiong, Yin, Jia-Xin, Xu, Su-Yang, Gao, Weibo, Chang, Guoqing

“…The ordinary and quantum Hall effects with fixed carrier types, electron or hole, exhibit well-defined chirality under external magnetic fields, but the analogous chirality of the quantum anomalous Hall effect (QAHE) remains little explored. …”
Get full text

Back to the Basics of SARS-CoV-2 Biochemistry: Microvascular Occlusive Glycan Bindings Govern Its Morbidities and Inform Therapeutic Responses by Scheim, David E., Parry, Peter I., Rabbolini, David J., Aldous, Colleen, Yagisawa, Morimasa, Clancy, Robert, Borody, Thomas J., Hoy, Wendy E.

“…Consistent with the biochemistry of coronaviruses as well established over decades, SARS-CoV-2 makes its initial attachment to host cells through the binding of its spike protein (SP) to sialylated glycans (containing the monosaccharide sialic acid) on the cell surface. …”
Get full text

A conserved arginine in NS5 binds genomic 3' stem-loop RNA for primer-independent initiation of flavivirus RNA replication by Wang, Sai, Chan, Kitti Wing Ki, Tan, Min Jie Alvin, Flory, Charlotte, Luo, Dahai, Lescar, Julian, Forwood, Jade K., Vasudevan, Subhash G.

“…We present virological and biochemical data showing the importance of this Arg 888 in virus viability and de novo initiation of RNA polymerase activity in vitro. Based on our binding studies, we hypothesize that ternary complex formation of NS5 with 3'SL, followed by dimerization, leads to the formation of the de novo initiation complex that could be regulated by the reversible zipping and unzipping of cis-acting RNA elements.…”
Get full text

Skyrmion-driven topological Hall effect in a Shastry-Sutherland magnet by Swain, N., Shahzad, M., Paradezhenko, G. V., Pervishko, A. A., Yudin, D., Sengupta, Pinaki

“…By constructing an effective tight-binding model of conduction electrons coupled to the skyrmion lattice, we clearly demonstrate the appearance of the topological Hall effect. …”
Get full text

Virus-like particles of nodavirus displaying the receptor binding domain of SARS-CoV-2 spike protein: a potential VLP-based COVID-19 vaccine by Kumar, Kiven, Tan, Wen Siang, Arshad, Siti Suri, Ho, Kok Lian

“…The efficacy of the initial vaccines based on the ancestral strain of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has become a point of contention due to the emergence of new variants of concern (VOCs). …”
Get full text

The FGFR inhibitor PD173074 binds to the C-terminus of oncofetal HMGA2 and modulates its DNA-binding and transcriptional activation functions by Ahmed, Syed Moiz, Ragunathan, Priya, Shin, Joon, Peter, Sabrina, Kleissle, Sabrina, Neuenschwander, Martin, Schäfer, Reinhold, Kries, Jens Peter V., Grüber, Gerhard, Dröge, Peter

Get full text

Structural and functional characterisation of the collagen binding domain of fibronectin by Millard, CJ

Identification of FGF receptor-binding peptides for cancer gene therapy by Maruta, F, Parker, AL, Fisher, KD, Hallissey, MT, Ismail, T, Rowlands, DC, Chandler, LA, Kerr, DJ, Seymour, LW

“…The consensus motif MXXP was iterated after four to five rounds and the peptide MQLPLAT was studied in depth. …”

Structural basis of RNA binding by leucine zipper GCN4 by Nikolaev, Yaroslav, Pervushin, Konstantin

“…To support further mechanistic studies, herein, we elucidated RNA binding interface of the GCN4 leucine zipper motif from yeast. …”
Get full text
Get full text

Binding modes of teixobactin to lipid ii : molecular dynamics study by Liu, Yang, Liu, Yaxin, Chan-Park, Mary Bee Eng, Mu, Yuguang

Get full text
Get full text