Development of high-affinity peptide-drug conjugates for investigating the TRIM24 PHD and bromodomain by Platt, MA

“…The PHD recognises trimethylated K9 (K9Me₃) through a non-canonical cation-π interaction with a solvent-exposed tryptophan (W828); while the BRD reads K18/23Ac <em>via</em> a hydrogen bonding interaction with an asparagine (N980). TRIM24 has been implicated in breast cancer development, and genetic knockdown of the protein was shown to have an antiproliferative effect in breast cancer cell lines, making it an attractive therapeutic target. …”

Evaporation of sessile saline droplet with surfactant on silicon wafer substrate by Yap, Ming Sheng

“…From 0.2mM to 0.8mM CTAB concentration, the evaporation process demonstrated CCR mode with the contact diameter at CCR and evaporation rate increases with higher CTAB concentration. On the other hand, at very low CTAB concentration, the evaporation process for 0.04mM CTAB undergoes a transition from mixed mode to constant contact angle (CCA) mode. …”
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Addressing Unmet Clinical Needs with UV Bioadhesives by O’Rorke, Richard D., Pokholenko, Oleksandr, Gao, Feng, Cheng, Ting, Shah, Ankur, Mogal, Vishal, Steele, Terry W. J.

“…Activated bioadhesives, on the other hand, allow control of when and where a bioadhesive cross-links and, in some cases, the extent of cross-linking. …”
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Halving premature death and improving quality of life at all ages by Norheim, OF, Chang, A, Bolongaita, S, Barraza-Lloréns, M, Jha, P, Lewington, S, Jamison, DT, Peto, R

“…Particular attention must be paid to countries with very low or a worsening rate of improvement in PPD. By reducing premature mortality, more people will live longer and more healthy lives. …”

Public bus transit service modeling and optimization: from conventional to autonomous vehicles by Tian, Qingyun

“…The passengers' adoption rate is considered in the transit assignment problem, and the problem is formulated as a bi-level programming model. …”
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Signal processing for cooperative cognitive radio networks by Rabiee, Ramtin

“…It is worth mentioning that the protection of primary signals, belonging to licensed users, is a crucial requirement in establishing of a CRN. On the other hand, conducting a strict sensing method may severely reduce the chance of a secondary network to utilize a free spectrum channel, where there is no point to using a CRN anymore. …”
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An experimental investigation on relation of stress with occurrence of tinnitus by Ng, Chee Seng.

“…Measurements that quantify the stress deriving from the biophysical signals include heart rate variability, pulse transit time and skin conductivity. …”
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Engineering a surface to enhance endothelial cell adhesion towards creating a 'roll-up' blood vessel prosthesis by Chua, Hui Yee.

“…The optimized gelatin “ink” allowed extended viability for the entrapped HUVECs and the drawn scaffold lines to retain their integrity whilst in growth media. …”
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Engineering control of rhizobacteria for plant growth promotion by Green, PWL

“…However, natural diazotrophs lack plant host specificity for root colonisation and employ multilayered regulatory mechanisms that couple the rate of nitrogen fixation with the assimilation of fixed nitrogen, preventing effective release of ammonia to the environment. …”

Person-centred care for dementia patients (backend system) by Lau, Wei De

“…Dementia is a disease that causes brain cells to die at an abnormal rate and affects the brain’s ability to function normally. …”
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Evaporation and crystallisation of saline droplet with surfactant on smooth surfaces by Wong, Dennis Kin Wai

“…On the other hand, concentric rings were observed at a high concentration of 0.8 mM CTAB with concentration of SDS below 6.4 mM SDS. …”
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Tumor cell-intrinsic signals promoting tolerance and adaptation to oncogenic kinase inhibition by Flower, Cameron Timothy

“…Using commonly prescribed TK inhibitors (TKIs), I show that TK genetic status generally predicts whether or not a cell line will show any response to genotype-matched TKI (GM-TKI), but is insufficient to predict drug tolerance, the ability of a cell line to sustain proliferation under drug. …”
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Performance monitoring for quantum key distribution systems by Yu, Timothy Shengrong

“…These limitations lead to the proposed development of a polarisation-encoded QKD system based on an adaptive polarisation state monitoring and recovery scheme that adapts the system to the existing polarisation drift condition in the transmission link to enhance its reliability and availability. On the other hand, current high-speed single-photon detection schemes are often designed to work with idealised parameters such as fixed gating rate and operating temperature. …”
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Energy-efficient video streaming over wireless networks by Chuah, Seong Ping

“…Meanwhile, datarate capacity of wireless links increases exponentially as wireless radio technology evolves from 2G to 4G. On the other hand, silicon technologies are empowering mobile devices with computing capability at exponential rate. …”
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A 110pJ/b multichannel FSK/GMSK/QPSK/p/4-DQPSK transmitter with phase-interpolated dual-injection DLL-based synthesizer employing hybrid FIR by Cheng, San-Jeow, Gao, Yuan, Toh, Wei-Da, Zheng, Yuanjin, Je, Minkyu, Heng, Chun-Huat

“…Hence, a reconfigurable TX that can support multichannel and multimodulation with reconfigurable data rate, spectrum and energy efficiency would be desirable. …”
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Experimental and numerical studies on the cooling of mobile device by Setoh, Guojing.

“…With the advancement in technology, consumers can expect mobile devices (cellular phones, laptop computers, PDA, etc.) to be packed with more complex components and features to satisfy consumer demand. On the other hand, the packaging of the mobile devices is made smaller, reducing the external surface area available for heat dissipation. …”
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Model study of the salt accumulation effect on the membrane performance in osmotic membrane bioreactor by Xiao, De Zhong

“…Such system exhibited very high rejection of various contaminants and mineral salts due to the nature of FO membrane. On the other hand, this high rejection also caused the accumulation of salts in the reactor which could have adverse impact on the biological activities as well as the membrane filtration performance. …”
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Thermal induced coupling of cell adhesion/deadhesion and migration under HBV replication and EGCG treatment by Li, Xi

“…The unique physical property of thermo-responsive polymer (TRP) has recently prompted its increasing applications in the applications of tissue engineering and regeneration medicine. On the other hand, TRP has never been exploited for their potential applications in quantitative cell screening against various external stimulations. …”
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Investment outlook for the medium range tanker segment from the perspective of a ship financier from 2011 to 2015 by Han, Peinan.

“…The research first examined the investment potential of MR tanker operating companies in the past by comparing their past return on equity (ROE) with shipping industry average and the companies required rate of return against S&P 500 calculated using CAPM model. …”
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Miniature jet engine compressor design and optimization by Goh, Aik Tio.

“…In particular, the decrease in the inlet hub radius and the backsweep angle were found to have significant positive impacts on the stage pressure ratio. On the other hand, an increase in the backsweep angle increased the compressor efficiency. …”
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