Duplex stem-loop-containing quadruplex motifs in the human genome: a combined genomic and structural study by Lim, Kah Wai, Jenjaroenpun, Piroon, Low, Zhen Jie, Khong, Zi Jian, Ng, Yi Siang, Kuznetsov, Vladimir Andreevich, Phan, Anh Tuan

“…Duplex stem-loops and four-stranded G-quadruplexes have been implicated in (patho)biological processes. Overlap of stem-loop- and quadruplex-forming sequences could give rise to quadruplex–duplex hybrids (QDH), which combine features of both structural forms and could exhibit unique properties. …”
Get full text
Get full text

Development of immunomodulatory RNA therapeutics for immune disorders by Iyer, Vaishnavi Srinivasan

“…Thus, paper III and paper IV focus on studying TCR specificities to gain a better understanding of the particular T cells that could be the culprits. …”
Get full text

Afiksasi verba dalam bahasa Indonesia by Rajeg, GPW, Denistia, K

“…This chapter offers new insights by presenting a description of the form, function and meaning of verb affixation based on a large collection of Indonesian digital texts (language corpora) of various text varieties in the last ten years. …”

Leveraging linguistic knowledge to enhance low-resource NLP applications by Zhu, Zixiao

“…As a result, several training paradigms have been developed to enhance the downstream performance of PLMs, as outlined below. …”
Get full text

Time-dependent metabolomics uncover dynamic metabolic adaptions in MCF-7 cells exposed to bisphenol A by Zhao, Haoduo., Liu, Min, Yang, Junjie, Chen, Yuyang, Fang, Mingliang

“…As one of the most phenotype-related omics, metabolome in response to environmental stress can vary from seconds to days. Up to now, very few dynamic metabolomics studies have been conducted to provide time-dependent mechanistic interpretations in understanding xenobiotics-induced cellular adaptations. …”
Get full text

Estrogenic post-menopausal anti-osteoporotic mechanism of Achyranthes aspera L.: Phytochemicals and network pharmacology approaches by Huq, AKM Moyeenul, Stanslas, Johnson, Nizhum, Nisarat, Uddin, Md. Nazim, Maulidiani, Maulidiani, Roney, Miah, Abas, Faridah, Jamal, Jamia Azdina

“…Hormone replacement therapy is used to treat postmenopausal syndrome caused by estrogen deficiency, but it has been linked to an increased risk of breast cancer. …”
Get full text

Proteomic network of antibiotic-induced outer membrane vesicles released by extensively drug-resistant Elizabethkingia anophelis by Chiang, Ming-Hsien, Chang, Fang-Ju, Kesavan, Dinesh Kumar, Vasudevan, Aparna, Xu, Huaxi, Lan, Kuo-Lun, Huang, Shu-Wei, Shang, Hung-Sheng, Chuang, Yi-Ping, Yang, Ya-Sung, Chen, Te-Li

“…Additionally, a protein-protein interaction network demonstrated that OMVs from imipenem-treated E. anophelis showed significant enrichments in the outer membrane, adenyl nucleotide binding, serine-type peptidase activity, the glycosyl compound metabolic process, and cation binding proteins. …”
Get full text

(宋代「武夷棹歌」中的地景空間與文化意蘊) = Landscape and culture in the Wu-yi Zhao Ge (Wu-yi boat song) of Song dynasty by 衣若芬 I, Lo-fen

“…He conducted lectures and provided enriching thinking to his followers for more than ten years, which has subsequently benefitted more than two hundred students. …”
Get full text
Get full text
Get full text

The proprietary consequences of fraud by Swadling, W

“…B, for example, knocks on A’s door falsely representing that they are collecting for charity; in truth, they believe that charity begins at home. If A hands over a £50 note, they will obviously have claims for compensatory damages against B in the tort of deceit and, alternatively, to be paid the value of their performance in unjust enrichment. …”

Characterization of nickel-titanium based thin films crystallized by fast and ultra-fast annealing methods by Motemani Sharabiani, Yahya

“…Ti39.6Ni46.1Hf14.3 and Ti42.3Ni42.5Hf15.2 are viii identified. The ability to control the transformation temperature through multiple thermal cycling has been demonstrated. …”
Get full text

Coordinated power management for islanded microgrids by Lin, Pengfeng

“…This thesis enriches the power sharing concepts in four aspects, i.e., transient power sharing, stable power sharing, bidirectional interlinking converters (BICs) distributed power sharing and economic power sharing. …”
Get full text

Stem Life: A Framework for Understanding the Prebiotic-Biotic Transition by Fournier, Gregory P.

“…Drawing from several natural history analogies, I show how this shift in perspective enriches our understanding of Origins and directly informs debates on defining Life, the emergence of the Last Universal Common Ancestor (LUCA), and the implications of prebiotic chemical experiments.…”
Get full text

Representation learning in the artificial and biological neural networks underlying sensorimotor integration by Suhaimi, Ahmad, Lim, Amos W. H., Chia, Xin Wei, Li, Chunyue, Makino, Hiroshi

“…Evaluation of thousands of neural network models with extensive hyperparameter search revealed that learning-dependent enrichment of state-value and policy representations of the task-performance-optimized deep RL agent closely resembled neural activity of the posterior parietal cortex (PPC). …”
Get full text

Advancing cyber incident timeline analysis through retrieval-augmented generation and large language models by Loumachi, Fatma Yasmine, Ghanem, Mohamed Chahine, Ferrag, Mohamed Amine

“…This paper introduces an innovative framework, GenDFIR, a context-specific approach powered via large language model (LLM) capabilities. …”
Get full text

Urban vulnerability assessment of sea level rise in Singapore through the World Avatar by Phua, Shin Zert, Lee, Kok Foong, Tsai, Yi-Kai, Ganguly, Srishti, Yan, Jingya, Mosbach, Sebastian, Ng, Trina, Moise, Aurel, Horton, Benjamin Peter, Kraft, Markus

“…We deploy computational agents to synthesise data from government, industry, and other publicly accessible sources, enriching buildings with metadata such as property usage, estimated construction cost, number of floors, and gross floor area. …”
Get full text

Distinctive antibody responses to Mycobacterium tuberculosis in pulmonary and brain infection by Spatola, M, Nziza, N, Irvine, EB, Cizmeci, D, Jung, W, Van, LH, Nhat, LTH, Ha, VTN, Phu, NH, Nghia, HDT, Thwaites, GE, Lauffenburger, DA, Fortune, S, Thuong, NTT, Alter, G

“…Machine learning methods were applied to characterize serum and CSF responses in TBM, identify prognostic factors associated with disease severity, and define the key antibody features that distinguish TBM from pulmonary TB. …”

Effective type label-based synergistic representation learning for biomedical event trigger detection by Hao, Anran, Yuan, Haohan, Hui, Siu Cheung, Su, Jian

“…Given its success in image classification, label representation learning is a promising approach to enhancing biomedical event trigger detection models by leveraging the rich semantics of pre-defined event type labels. Results: In this paper, we propose the Biomedical Label-based Synergistic representation Learning (BioLSL) model, which effectively utilizes event type labels by learning their correlation with trigger words and enriches the representation contextually. …”
Get full text

Magnetic nanochain enabled microarray and microfluidic bioassays by Xiong, Qirong

“…Importantly, PDA not only serves as the scaffold to lock the nanochain structure, but also allows for convenient surface functionalization by means of spontaneous Michael addition and/or Schiff base reaction with nucleophilic thiol and amine groups. …”
Get full text
Get full text