Inhibition of endoplasmic reticulum stress using 4-phenyl butyrate mitigates osteoporosis in a mouse model of hindlimb suspension by Al-Daghestani, Hiba Saad Subhi

“…Osteoporosis (OP) characterized by micro-architectural deterioration of bone tissue is a common skeletal disease in the elderly and may lead to fragility fractures. …”
Get full text

3D patient specific instrumentation for high tibial osteotomy by Wong, Gina Khay Fong

“…The most time-intensive part of this project is creating the bone models as there are many alternatives to build it, with many unknown variables, like how the detection algorithm for the Hounsfield Units (HU) works, which helps to build the bone model. …”
Get full text

A Novel Approach to Open Reduction and Internal Fixation of Distal Radius Fractures Utilizing a Multi-Degree-of-Freedom Traction and Stabilization Device by Oeding, Jacob F., Bockman, Sam, Chiu, Harriet, Hua, Cheyenne, Connor, James, Slocum, Alexander

“…Open reduction and internal fixation (ORIF) is a surgical procedure performed with the objectives of restoring normal alignment and providing stability to broken bone fragments after a fracture. This procedure is increasingly used to treat fractures of the distal end of the radius. …”
Get full text

Characterisation of collagen type I/ type II composite scaffolds for osteochondral tissue engineering by Tamaddon, M

“…The goal of this thesis was to develop and characterise the layers of an osteochondral scaffold following the composition and structure of cartilage, the cartilage-bone interface and underlying bone to treat osteoarthritis or defects in bone and cartilage. …”

Cellular reporter for inflammation. by Yuhanis Abdullah Sunny.

“…We had found that our reporter could clearly show GFP expression well when the transduced bone marrow cells were induced to undergo inflammation. …”
Get full text

Living with fibrodysplasia ossificans progressiva: radiological images of a patient with extensive heterotopic ossification by Mohammed Mostafa Kotb, Omar, Usama Farghaly, Kaliya-Perumal, Arun-Kumar

“…Fibrodysplasia ossificans progressiva (FOP) is an exceptionally rare genetic disorder characterized by the progressive formation of heterotopic bone in soft tissues. Here, we present the radiological findings of an 18-year-old female diagnosed with FOP who had severe spinal and right-upper-limb abnormalities. …”
Get full text
Get full text

Starting from scratch by Koh, Bernice Jia Hong, Goh Shun Jie, Tan, Benjamin, Tan, Joanne Li Ling

“…Based on research findings, the problem statement was identified, which helped hone the campaign’s strategy, tactics and goals. …”
Get full text

Knee joint measurement using CT scans for knee joint implant selection by Jing, Mei

“…With the help of the cutting guide, the surgeon cuts several pieces of bone from the end of the femur in order to match the implant shape, that’s called shaping the distal femoral bone. …”
Get full text

Translational GTPase BipA is involved in the maturation of a large subunit of bacterial ribosome at suboptimal temperature by Goh, Kwok Jian, Ero, Rya, Yan, Xin-Fu, Park, Jung Eun, Kundukad, Binu, Zheng, Jun, Sze, Siu Kwan, Gao, Yong-Gui

“…Based on the growth curve, soft agar swimming assay, and sucrose gradient sedimentation analysis, mutation of the catalytic residue His78 rendered plasmid-borne bipA unable to complement its deletion phenotypes. …”
Get full text

Neutrophil‐mediated enhancement of angiogenesis and osteogenesis in a novel triple cell co‐culture model with endothelial cells and osteoblasts by Herath, Thanuja D. K., Larbi, Anis, Teoh, Swee Hin, Kirkpatrick, C. James, Goh, Bee Tin

“…Repair and regeneration of critical‐sized bone defects remain a major challenge in orthopaedic and craniomaxillofacial surgery. …”
Get full text

New method for automatic generation of patient specific finite element models of the distal femur by Lek, Cheah Wen.

“…For model validation, the cortical bone was model with four-node shell elements while eight-node hexahedral elements and six-node wedge elements were used to model the cancellous bone. …”
Get full text

A medical image-based computer-aided diagnosis system for musculoskeletal disease and disorder. by Chuah, Tong Kuan

“…As part of the advancement to classifying subjects with BML, the thesis investigated textural parameters as potential biomarker in separating between bone marrow with and without bone marrow lesion. …”
Get full text

The hollow fiber bioreactor as a stroma-supported, serum-free ex vivo expansion platform for human umbilical cord blood cells by Xue, Cao, Kwek, Kenneth Y. C., Chan, Jerry Kok Yen, Chen, Qingfeng, Lim, Mayasari

“…The bone marrow microenvironment plays an integral role in the regulation of hematopoiesis. …”
Get full text
Get full text
Get full text

From the Andes to the coast: human mobility and diet in the Atacama desert during the late intermediate period (ad 900-1450) by Santana Sagredo, F

“…Human remains were analysed for tooth enamel, bone collagen, bone apatite, and hair-keratin. A second aim of the thesis was to provide new analysis of archaeological plants and animals of the area. …”

The impact of natural climate variability on the global distribution of Aedes aegypti: a mathematical modelling study by Kaye, AR, Obolski, U, Sun, L, Hart, WS, Hurrell, JW, Tildesley, MJ, Thompson, RN

“…Some regions could experience vector-borne disease outbreaks earlier than expected under climate change alone. …”

In vitro bioactivity and biocompatibility assessment of PCL/PLA–scaffolded mesoporous silicate bioactive glass: role of boron activation by Md. Zain, Siti Khalijah, Sazali, Ezza Syuhada, Ghoshal, Sib Krishna, Hisam, Rosdiyana

“…Bioactive glasses with rapid biodegradation and efficient biomineralization for damaged bone tissue repair remain deficient. Based on this fact, some new types of boron-activated mesoporous Bioactive silicate glasses (BMSGs) were made to determine the feasibility of achieving their improved mechanical strength, structure, porosity, biodegradability and bone healing performance. …”

Experimental investigation into load settlement characteristics of piled rafts in sand by Leong, Hazel Xueling.

“…Studies by many notable researchers in the years to come suggest that the most effective combinations of piles and raft happens when all the initial loading can be borne with the raft’s bearing capacity alone. The role of the piles was solely to reduce the excessive settlement experienced by the plain raft.…”
Get full text

The 'Clisurean' finds from Climente II cave, Iron Gates, Romania by Bonsall, C, Boroneanţ, A, Evatt, A, Soficaru, A, Nica, C, Bartosiewicz, L, Cook, G, Higham, TFG, Pickard, C

“…Single-entity 14C dating of human bone and humanly modified animal bones suggests the Clisurean occupation occurred during the Bølling–Allerød warm period. …”

Causal inference in health and disease: a review of the principles and applications of Mendelian randomization by Lovegrove, CE, Howles, SA, Furniss, D, Holmes, MV

“…This review provides a framework to enhance understanding of how MR may be used to triangulate evidence and progress research in bone and mineral metabolism as we strive to infer causal effects in health and disease.…”

15.280 Communication for Managers, Fall 2008 by Hartman, Neal

“…Students may also enroll in 15.277 Special Seminar in Communication: Leadership and Personal Effectiveness Coaching. 15.280 is offered for 6 units and 15.277 provides an additional 3 units for a total of 9 units in Managerial Communication. 15.277 acts as a lab component to 15.280 and provides students additional opportunities to hone their communication skills through a variety of in-class exercises.…”
Get full text