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3581
Synthetic, spectroscopic, biological and X-ray crystallographic structural studies on a novel pyridine-nitrogen-bridged dimeric nickel(II) complex of a pentadentate N3S2 ligand
Published 2001“…The anticancer properties of these compounds were also evaluated against Human T-lymphoblastic leukaemia cell lines. The Schiff base exhibits marked cytotoxicity against these cells, but its nickel(II) complex is inactive.…”
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Article -
3582
Empowering Teen Mental Fitness : A Guide for Managing Addiction, Eating Disorders, OCD, and Trauma /
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software, multimedia -
3583
Characterizing dry mass and volume changes in human multiple myeloma cells upon treatment with proteotoxic and genotoxic drugs
Published 2023“…We show that human MM cell lines (RPMI8226, MM.1S, KMS20, and AMO1) increase dry mass upon bortezomib treatment. …”
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Article -
3584
A low-cost, open-source cylindrical Couette rheometer
Published 2024“…As a result, rheometers are typically large, expensive, and require additional infrastructure (e.g., gas lines), rendering them inaccessible for regular use by many individuals, small organizations, and educators. …”
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Article -
3585
Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans
Published 2018“…METTL8, however, modified only mRNA, as determined by biochemical and genetic analyses in Mettl8 null-mutant mice and two human METTL8 mutant cell lines. Our findings provide the first evidence of the existence of m3C modification in mRNA, and the discovery of METTL8 as an mRNA m3C writer enzyme opens the door to future studies of other m3C epitranscriptomic reader and eraser functions.…”
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Journal Article -
3586
Holocene rate of slip and tentative recurrence interval for large earthquakes on the San Andreas fault, Cajon Pass, southern California
Published 2013“….; it has provided tentative evidence for 6 earthquakes in about the past 1,000 yr. Both lines of evidence suggest an average recurrence interval for large earthquakes of ∼1½ to 2 centuries. …”
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Journal Article -
3587
Who learns when workers are trained? a case of safety training of maintenance contractors’ workers for a major petrochemical plant shutdown
Published 2003“…The curves obtained are typical for the whole exercise, which gave perfect straight lines for Introduction to Safety, Hydrogen Sulphide, Confine Space and Permit to Work, respectively. …”
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Article -
3588
A novel human stem cell platform for probing adrenoceptor signaling in iPSC derived cardiomyocytes including those with an adult atrial phenotype
Published 2017“…</p> <p>Drug targeting of atrial-specific ion channels has been difficult because of lack of availability of appropriate cardiac cells, and preclinical testing studies have been carried out in non-cardiac cell lines, heterogeneous cardiac populations or animal models that have been unable to accurately represent human cardiomyocyte physiology. …”
Thesis -
3589
An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps and...
Published 2024“…Steady and unsteady casing static pressure measurements were acquired, using pneumatic lines and high-frequency response (∼100 kHz) Kulite pressure transducers respectively. …”
Conference item -
3590
Inflammation and colorectal cancer: elucidation of the cellular and molecular mechanisms by which interleukin 22 contributes to the development and progression of colorectal cancer
Published 2017“…Using a panel of CRC cell lines and primary human organoids, we confirmed that this prognostic association is due to a functional interaction between IL-22 and mutant KRAS by observing that IL-22 enhances chemoresistance, 3-dimensional clonogenicity, and proliferation specifically in CRC cells with both high IL-22 receptor levels and <em>KRAS</em> mutations. …”
Thesis -
3591
Citizenship and the politics of poverty definition during the segregation, apartheid and democratic eras in South Africa: 1910-2010
Published 2013“…The Household Subsistence Level (HSL) and the Minimum Living Level (MLL) were derivatives of the PDL (the HSL was exactly the PDL, the MLL was lower in value) and were conceptually similar were used as poverty definitions and poverty lines to fix the wages of black workers, thus showing the link between the denial of citizenship and the politics of poverty definition.…”
Thesis -
3592
Assessing the kinetics of oxygen-unloading from red cells using FlowScore, a flow-cytometric proxy of the functional quality of blood
Published 2025“…Applying FlowScore to data from the COMPARE study revealed a positive association with the time-delay from sample collection to measurement, which was verified experimentally. The LifeLines dataset revealed age, sex, and smoking among factors affecting FlowScore. …”
Journal article -
3593
Dress, Feminism, and British New Woman Novels
Published 2018“…For example, Grand elevated cross-class feminism, but she belittled middle-class women's taste, side-lined poor women’s most pressing sartorial concerns, and dressed to impress. …”
Thesis -
3594
A move
Published 2024“…It includes viewpoints from an old father who has lost his authority, the eldest son who longs for power, and various female family members. …”
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Thesis-Master by Coursework -
3595
Performance-based identity in a BIM environment : An architect’s perceptions and experiences
Published 2022“…Consequently, architects' failing to adapt their core identity to the varying circumstances may lead to their irrelevance and being side-lined merely as aesthetic building surgeons. The current study therefore seeks a better understanding of their perceptions and experiences in manifesting their identities in the phenomenon. …”
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Article -
3596
Tablets, Pens, and Pencils: The Influence of Tools on Sketching in Early Stage Design
Published 2024“…We hypothesize that participants using tablet and pencil will produce fewer drawings than those using pen due to their ability to erase and focus on perfecting drawings, and we expect participants using the tablet to produce cleaner drawings with smoother strokes due to the tablet’s ability to auto-smooth lines. Based on prior literature, we posit that women and gender minorities will produce fewer sketches and use the feathering style of sketching more than men.…”
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Article -
3597
Regulation of microRNA degradation in Caenorhabditis elegans via the E3 ubiquitin ligase EBAX-1
Published 2024“…TDMD underlies the instability of many miRNAs in diverse cell lines and animals. In this work, I probe the biological scope of TDMD as a regulatory mechanism in the nematode Caenorhabiditis elegans, which tolerates homozygous loss of the ZSWIM8 ortholog, EBAX-1, and expresses some miRNAs that are subject to rapid, developmentally regulated decay. …”
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Thesis -
3598
Development of immunomodulatory RNA therapeutics for immune disorders
Published 2022“…We show that these ASOs can modulate T cell behavior in human cell lines and human primary cells, validating the potential of ASOs as a therapeutic approach for immune diseases. …”
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Thesis-Doctor of Philosophy -
3599
Data-driven distributionally robust CVaR portfolio optimization under a regime-switching ambiguity set
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Journal Article -
3600
Financial forecasting using meta-cognitive fuzzy neural networks
Published 2014“…The primary meta-cognitive strategies are Sample deletion, Sample Learning and Sample Reserve. Following on the lines of Technical Analysis carried out by traders and investors on the historical prices of a company’s stock, the project makes use of various Financial Indicators to decide whether a particular instance of time is good for investment, disinvestment or to remain idle. …”
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Final Year Project (FYP)