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The yeast FIT2 homologs are necessary to maintain cellular proteostasis and membrane lipid homeostasis
Published 2022“…While LD biogenesis and basal endoplasmic reticulum (ER) stress-induced unfolded protein response (UPR) remain unaltered in ScFIT mutants, SCS3 was found to be essential for proper stress-induced UPR activation and for viability in the absence of the sole yeast UPR transducer IRE1 Owing to not having a functional UPR, cells with mutated SCS3 exhibited an accumulation of triacylglycerol within the ER along with aberrant LD morphology, suggesting that there is a UPR-dependent compensatory mechanism that acts to mitigate lack of SCS3 Additionally, SCS3 was necessary to maintain phospholipid homeostasis. …”
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Journal Article -
22
Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community
Published 2024“…Genome-scale metabolic models (GEMs) can facilitate metabolism-focused multi-omics integrative analysis. Since Yeast8, the yeast-GEM of Saccharomyces cerevisiae, published in 2019, has been continuously updated by the community. …”
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Journal Article -
23
Genetic, genomic and systems biology analysis of adaptive evolution of budding yeast to the deletion of essential genes
Published 2016“…However previous studies in budding yeast challenged this view by showing that mutants deleted of essential or non-essential genes are capable of accumulating compensatory mutations and resume viability, suggesting that essentiality is not an intrinsic gene property but depends on the cellular capacity to evolve. …”
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Research Report -
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Identifying antifungal resistance mechanisms and modes of action using SAturated Transposon Analysis in Yeast (SATAY)
Published 2024Subjects:Thesis -
26
The Iran nuclear deal : rewriting the middle east map
Published 2014“…The agreement to resolve the Iranian nuclear programme could rewrite the political map of the Middle East and North Africa, as well as strengthen the US pivot to Asia. …”
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Commentary -
27
Negotiating access to populations of concern in South-East Asia
Published 2019Subjects: Get full text
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Journal Article -
28
East Asian energy supply, demand and cooperation outlook
Published 2015Get full text
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Book Chapter -
29
The Global Financial Tsunami: implications for East Asian economies
Published 2015Subjects: “…DRNTU::Humanities::History::Asia::East Asia…”
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Book Chapter -
30
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31
Can the war on Iraq bring democracy to the Middle East?
Published 2008“…As a result, the idea of a democratic Middle East is facing criticism. This study will also show that such projects are both uncertain and vital.…”
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Thesis -
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India's comprehensive economic engagement with east and southeast Asia.
Published 2011Get full text
Thesis -
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Russia's crimean annexation : what it means for East Asia
Published 2014“…Moscow’s annexation of Crimea and continuing tensions over Ukraine have global ramifications extending to East Asia.…”
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Commentary -
35
Middle East upheavals: more politics than religion
Published 2016“…This is partly due to power shifts in the Middle East and the consequent response of a struggle for a new political order.…”
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Commentary -
36
Singapore as Asia’s LNG Hub: Bridge with East Africa?
Published 2016“…As Singapore grows as an oil and LNG trading hub in Asia, East Africa is developing its huge potential as a natural gas producer. …”
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Commentary -
37
Malaysia’s East Coast Rail Link: Bane or Gain?
Published 2017Subjects: Get full text
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Commentary -
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South Asia's trade policy : adopt East Asian approach
Published 2021“…South Asian countries must adopt the East Asian approach of signing Free Trade Agreements (FTAs) to enhance market access and to link their economies to regional and global supply chains. …”
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Commentary