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Biotin-streptavidin binding interactions of dielectric filled silicon bulk acoustic resonators for smart label-free biochemical sensor applications
Published 2014“…Sensor performance of a dielectric filled silicon bulk acoustic resonator type label-free biosensor is verified with biotin-streptavidin binding interactions as a model system. …”
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Journal Article -
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Biocementation of sand filled geotextile tubes
Published 2019“…Nonetheless, the strength and durability of geotextile tubes that filled with sand or clay slurry still need to be improved. …”
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Final Year Project (FYP) -
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Can't Hurt Me : Master Your Mind and Defy the Odds /
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software, multimedia -
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Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics
Published 2014“…Loop 1 occupies two major conformational states: extended and recessed; the former but not the latter displays correlations in atomic fluctuations with those of loop 2 (~24 Å apart). Since loop 1 binds to the major groove whereas loop 2 binds to the minor groove of DNA, our results begin to provide some insight into the possible mechanism underpinning the cooperative nature of DBD binding to DNA. …”
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Journal Article -
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Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore
Published 2020“…Background: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular evolution and receptor-binding specificity. …”
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Journal Article -
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Ideal houses : a visual research case study on factors that define a house.
Published 2011“…To what extent can the creative mind bring about new notions on the urban living environment or cast light upon current circumstances? …”
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Final Year Project (FYP) -
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Starting from scratch
Published 2016“…With the campaign’s branding and identity in mind, the considerations were clear that the campaign needed to be relevant to teenagers with and without eczema. …”
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Final Year Project (FYP) -
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Enzymatic preparation of diacylglycerols: lipase screening, immobilization, characterization and glycerolysis performance
Published 2024“…Backgrounds: Glycerolysis, with its advantages of readily available raw materials, simple operation, and mild reaction conditions, is a primary method for producing diacylglycerol (DAG). …”
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Anisotropic protein diffusion on nanosurface
Published 2022“…On the MBP surface, HP35 migrates mainly along the zigzag direction but can also easily stride over the ridges and grooves along the armchair direction. Moreover, the mild binding strength between α-PC and HP35 does not cause distortion in the protein structure. …”
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Journal Article -
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Bifunctional diazirine reagent for covalent dyeing of Kevlar and inert polymer materials
Published 2024“…The reagent's structure features a trifluoromethyl diazirine group as a precursor to a carbene that binds the textile surface. On the reagent's other terminus, a benzyl bromide group acts as a site accessible for substitution reactions. …”
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Identification of novel functional compounds from forest onion and its biological activities against breast cancer
Published 2024“…A natural resource with potential activity against breast cancer is forest onion, Eleutherine bulbosa (Mill.) Urb., but the identity of its active constituents and their mechanisms of action remain unexplored. …”
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Elucidating the mechanism of mRNA transport using novel imaging technologies
Published 2023“…The MS2-MCP system is used to insert into mRNAs of interest special structures to which RNA-binding proteins, fused to a fluorescent protein such as GFP, can then bind. …”
Thesis -
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Methods for the Study of Galactofuranose in Mycobacteria
Published 2024“…Finally, we characterized the kinetics of a mild electrophile, the squaric ester, and assessed its utility in selectively binding and modifying a key galactofuranosyl transferase involved in mycobacterial cell wall biosynthesis. …”
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Thesis -
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Vypal2: a versatile peptide ligase for precision tailoring of proteins
Published 2022“…The last two decades have seen an increasing demand for new protein-modification methods from the biotech industry and biomedical research communities. Owing to their mild aqueous reaction conditions, enzymatic methods based on the use of peptide ligases are particularly desirable. …”
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Journal Article -
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Seroprevalence of SARS-CoV-2 in children and adolescents
Published 2023“…</p> <br> <p>The findings of ‘STORY’ confirm that SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalisation. …”
Thesis -
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Experimental Characterization of Iron-Sulfur Cluster Excited States and their Relevance to Electron Transfer Reactions
Published 2024“…We find additionally that the primary coordination sphere has a strong influence on the topography of these excited state landscapes, in particular that the donor properties of the ligands binding an [Fe₄S₄]¹⁺ cluster determine its ground state valence electron distribution. …”
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Thesis -
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Methyl and dimethyl o-xylenyl-substituted fullerene acceptors for polymer solar cells
Published 2015“…These values correlate with the binding affinities of the fluorophore and quencher. …”
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Journal Article -
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Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
Published 2024“…Sustained mechanostimuli increase the levels of binding-immunoglobulin protein (BiP) expression and phosphorylated eIF2α, two markers for ER stress. …”
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Journal Article -
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Crack healing in reactive MgO-slag system via bacteria induced carbonate precipitation
Published 2021“…In the Concrete industry, the most widely used binding ingredient for concrete, portland cement (PC), is accountable for around 8% of global anthropogenic carbon dioxide (CO2) emissions. …”
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Final Year Project (FYP)