Loss of caveolin-1 impairs light flicker-induced neurovascular coupling at the optic nerve head by Loo, Jing Hong, Lee, Ying Shi, Woon, Chang Yi, Yong, Victor H. K., Tan, Bingyao, Schmetterer, Leopold, Chong, Rachel S.

“…However, there was no significant difference in RGC density between Cav-1 KO and wild type mice. These findings highlight the role of Cav-1 in regulating neurovascular coupling and IOP and suggest that the loss of Cav-1 may predispose to vascular dysfunction and decreased RGC signaling in the absence of structural loss. …”
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The role of PTEN in human bone marrow-derived mesenchymal stem cells mediated tumor cells suppression. by Toh, Xin Yi.

“…In parallel, isogenic glioma cell lines U251, which overexpresses wild-type PTEN upon tetracycline treatment, resulted in 1.43-fold glioma cell growth retardation when cultured in the presence of MSC. …”
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Gobo: A System for Exploring User Control of Invisible Algorithms in Social Media by Bhargava, Rahul, Chung, Anna, Gaikwad, Neil S, Hope, Alexis, Jen, Dennis, Rubinovitz, Jasmin, Saldías-Fuentes, Belén, Zuckerman, Ethan

“…Through an iterative design process, we've built and deployed Gobo in the wild and conducted a pilot study in the form of a survey to understand how the users respond to the shift of control from invisible algorithms to themselves. …”
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Wear and friction properties of pineapple leaf fibers-reinforced natural rubber composites with the influence of multi-walled carbon nanotubes by Xuan, Yeo Yi, Ridzuan, M.J.M., Abdul Majid, M.S., Syayuthi, A.R.A., Mat, Fauziah, Salit @ Sinon, Mohd Sapuan

“…The PALF content was ranged from 0, 10, 20 to 30 parts per hundred rubber (phr) while the MWCNT content was maintained at 10 phr. A two-roll mill mixing process followed by molding was employed to fabricate the NR composites. …”
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Sorptive properties of biofilm matrix for heavy metal sequestering by Elisa Tiaras

“…The characteristics and the ability to treat heavy metals in 4 strains, namely PAO1 wild-type, ΔPelA strain, ΔPslBCD strain and double mutant ΔPelA- ΔPslBCD strain, were compared in the study. 2 types of metals that are commonly found in the environment were used in the study: copper (Cu) and zinc (Zn). …”
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We’re too busy singing: acoustic analysis with apes by French, Fiona, Good, Stephen, Mokkadem, Karim, Frost, Naomi, Finch, Katherine

“…Ultimately, we are planning a deeper investigation of auditory perception, by developing interactive devices that offer agency to non-humans and enable us to find out more about the hearing capabilities of different species.…”
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Enhanced restoration of visual code after targeting ON bipolar cells compared to retinal ganglion cells with optogenetic therapy by Rogers, J, Hughes, S, Ebrahimi, A, Allen, A, Storchi, R, Lindner, M, Peirson, S, Badea, T, Hankins, M, Lucas, R

“…Our data show that, while both approaches restore visual responses with impressive fidelity, ON BC targeting produces a richer visual code closer to that of wild-type mice. …”

Urban-rural communities attitudes and perceptions toward wildlife meat consumption in Bintulu, Sarawak by Thomas, Alexander, Mariapan, Manohar, Lim, Evelyn Ai Lin, Johari, Shazali

“…Among the wildlife meat, wild boar meat is the most preferred. The findings provide guidance towards developing successful strategies and actions to influence local communities towards sustainable use of wildlife for consumption.…”

Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes by Zarei, Mohammad, Barroso, Emma, Palomer, Xavier, Escolà-Gil, Joan Carles, Cedó, Lidia, Wahli, Walter, Vázquez-Carrera, Manuel

“…Finally, treatment with another PPARβ/δ agonist increased VLDLR levels in the liver of wild-type mice, but not PPARβ/δ-deficient mice, confirming the regulation of hepatic VLDLR by this nuclear receptor. …”
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Genotype-phenotype maps for gene networks: from evolution to computation by Camargo, FQ

“…For both modelling frameworks, the GRN GP maps exhibit all the structural properties found in the literature, as well as simplicity bias. We also find that the number of genotypes mapping to the wild-type phenotypes for various GRNs is unusually large, and argue that this is evidence that the structure of the GP map plays an important role in determining evolutionary outcomes.…”

Strategies to mitigate establishment under the Wolbachia incompatible insect technique by Soh, Stacy, Ho, Soon Hoe, Ong, Janet, Seah, Annabel, Dickens, Borame Sue, Tan, Ken Wei, Koo, Joel Ruihan, Cook, Alex R., Sim, Shuzhen, Tan, Cheong Huat, Ng, Lee Ching, Lim, Jue Tao

“…Our simulations indicate that these interventions do not override the intended wild type suppression of the IIT approach. These findings will inform policy makers of possible ways to mitigate the potential establishment of Wolbachia using the IIT population control strategy.…”
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Biochemical characterisation of NS2B-NS3 protease from flaviviruses by Nah, Jojo Qian Hui

“…Here, we compared the enzymatic activities of DENV NS2B47- G4SG4 NS3 Wild Type (WT) pro, DENV NS2B47- G4SG4 NS3WTSSpro with DENV NS2B47- G4SG4 NS3WTSS and Zika virus (ZIKV) NS2B-NS3 WT pro. …”
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新加坡当代社会同志自由的研究 = A study of homosexuals’ liberty in present day Singapore by 陈惠嫔 Tan, Mabel Hui Ping

“…Analysis of credible survey results and reports, as well as gathering personal anecdotes and surveys from respondents was done. Findings were analyzed in an attempt to understand and explain how the tension between the individuals and society at large works. …”
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DOK3 promotes atopic dermatitis by enabling the phosphatase PP4C to inhibit the T cell signaling mediator CARD11 by Loh Jia Tong, Teo, Joey Kay Hui, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Andiappan, Anand Kumar, Lim, Hong-Hwa, Lam, Kong-Peng

“…A subset of hypomorphic CARD11 variants found in patients with atopic dermatitis bound more strongly than wild-type CARD11 to DOK3. Our findings suggest that the strength of the interaction of DOK3 with CARD11 may predispose individuals to developing atopic dermatitis.…”
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A multi-view context-aware approach to Android malware detection and malicious code localization by Narayanan, Annamalai, Chandramohan, Mahinthan, Chen, Lihui, Liu, Yang

“…Subsequently, it employs Multiple Kernel Learning (MKL) to find a weighted combination of the views which yields the best detection accuracy. …”
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Dynamic boundaries of acceptable play: a mixed methods examination into players' interpretations of toxic behavior in multiplayer online games by Yu, Valerie Jingwen

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PPARβ/δ prevents endoplasmic reticulum stress-associated inflammation and insulin resistance in skeletal muscle cells through an AMPK-dependent mechanism by Salvadó, Laia, Barroso, Emma, Gómez-Foix, Anna Maria, Palomer, Xavier, Michalik, Liliane, Wahli, Walter, Vázquez-Carrera, Manuel

“…Methods Studies were conducted in mouse C2C12 myotubes, in the human myogenic cell line LHCN-M2 and in skeletal muscle from wild-type and PPARβ/δ-deficient mice and mice exposed to a high-fat diet. …”
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Application of in vitro erythropoiesis from bone marrow derived progenitors to detect and study genotoxicity by Shuga, Joseph F. (Joseph Francis)

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Global response of Vibrio cholerae to predation by heterotrophic protists by Hu, Jie

“…Indeed, a pigmented mutant, disrupted in VC1345 (hmgA), survived 100-fold better intracellularly in amoebae than did the wild type. The biomass of V. cholerae biofilms increased when the cell-free supernatant from a T. pyriformis culture was added, indicating that there may be chemical cues involved. …”
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TEOSINTE BRANCHED1/CYCLOIDEA/PROLIFERATING CELL FACTOR4 Interacts with WRINKLED1 to mediate seed oil biosynthesis by Kong, Que, Singh, Sanjay K., Mantyla, Jenny J., Pattanaik, Sitakanta, Guo, Liang, Yuan, Ling, Benning, Christoph, Ma, Wei

“…Collectively, our findings suggest that TCP4 represses fatty acid biosynthetic gene expression through interaction with AtWRI1, leading to a reduction of AtWRI1-mediated seed oil accumulation.…”
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