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    PPARβ/δ agonism upregulates forkhead box A2 to reduce inflammation in C2C12 myoblasts and in skeletal muscle by Phua, Wendy Wen Ting, Tan, Wei Ren, Yip, Yun Sheng, Hew, Ivan Dongzheng, Wee, Jonathan Wei Kiat, Cheng, Hong Sheng, Leow, Melvin Khee Shing, Wahli, Walter, Tan, Nguan Soon

    Published 2020
    “…This reduced local inflammatory response limits tissue damage and restores muscle tetanic contraction. In line with these results, a deficiency in either PPARβ/δ or FoxA2 diminishes the action of the PPARβ/δ agonist GW501516 to suppress an aggravated inflammatory response. …”
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    Journal Article
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