Sequence- and structure-specific probing of RNAs by short nucleobase-modified dsRNA-binding PNAs incorporating a fluorescent light-up uracil analog by Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Meng, Zhenyu, Ong, Alan Ann Lerk, Wang, Zhenzhang, Lu, Yunpeng, Xia, Kelin, Prabakaran, Mookkan, Chen, Gang

“…Compared to DNA and RNA, peptide nucleic acids (PNAs) are chemically stable and have a neutral peptide-like backbone, and thus, they show significantly enhanced binding to natural nucleic acids. We have successfully developed nucleobase-modified dsRNA-binding PNAs (dbPNAs) to facilitate structure-specific and selective recognition of dsRNA over single-stranded RNA (ssRNA) and dsDNA regions at near-physiological conditions. …”
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Fragmenstein: predicting protein–ligand structures of compounds derived from known crystallographic fragment hits using a strict conserved-binding–based methodology by Ferla, MP, Sánchez-García, R, Skyner, RE, Gahbauer, S, Taylor, JC, von Delft, F, Marsden, BD, Deane, CM

“…Current strategies centred on either merging or linking initial hits from fragment-based drug design (FBDD) crystallographic screens generally do not fully leaverage 3D structural information. …”

Harnessing dimethyl ether with ultra-low-grade heat for scaling-resistant brine concentration and fractional crystallization by Foo, Zi Hao, Deshmukh, Akshay, Wilson, Aaron D., Lienhard, John H.

“…Solvent-driven separations may enable scalable concentration of hypersaline brines, supporting a circular resource economy from the extraction of lithium and rare earth elements from spent battery and magnet leachates. …”
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No culture left behind: ArtELingo-28, a benchmark of WikiArt with captions in 28 languages by Mohamed, Y, Li, R, Ahmad, IS, Haydarov, K, Torr, P, Church, KW, Elhoseiny, M

“…Traditionally, vision research focused on unambiguous class labels, whereas ArtELingo-28 emphasizes diversity of opinions over languages and cultures. The challenge is to build machine learning systems that assign emotional captions to images. …”

Building wireless sensor network: prototype datalogging enhancement & development as a real-time modelling device by Tay, Owen Jia Hao

“…Key performance metrics, including R2, Cross Validation Score Mean (CVSM), Mean Squared Error (MSE), Root Mean Squared Error (RMSE), and Mean Absolute Error (MAE), are employed to evaluate accuracy and stability over time. The findings underscore the consistent and superior performance of the KNN model in contrast to OLS & PR. …”
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The susceptibility of Malaysian rice brands to Sitophilus oryzae and the potential application of zinc oxide nanoparticles for control purposes by Nurin Nazifa Syanizam, Siti Khadijah Mohd Bakhori, Siti Nasuha Hamzah

“…Nanoparticle insecticides are created and studied to replace the overly-used synthetic chemical insecticides. The purpose of this study is to investigate the susceptibility of several commercialized rice brands towards S. oryzae infestation and to assess the toxicity of different types of zinc oxide (ZnO) against S. oryzae. …”
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QoS provisioning by power control for video communication via satellite links by Ma, Ting, Lee, Yee Hui, Winkler, Stefan, Ma, Maode

“…Video transmissions over satellite links are sensitive to signal fades because of rain, especially in the tropics. …”
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Rediscovering Homo sapiens in international politics: evolution and rationality’s missing link by Johnson, D

Tailoring the properties of shape memory polymers via UV cross-linking by Gay, Angela Shi Hui

“…Characteristics such as the crystallisation and effects when cured over different filters. The experiments are performed using mechanical testing devices such as Dynamic Mechanical Analysis (DMA) and Differential Scanning Calorimetry (DSC). …”
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A guide to being the elephant in the room : a study on the residual behaviours stemming from bodyweight stigma by Jayakumar Sandhya Pillai

“…From a very young age, I was hyper-aware of the fact that traversing this world in a bigger body would result in lower social capital, hyper visibility and sexual invisibility. …”
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Towards a consensus on dyslexia: findings from a Delphi study by Carroll, JM, Holden, C, Kirby, P, Thompson, PA, Snowling, MJ, Dyslexia Delphi Panel

“…There have been many definitions over the past century and debate continues as to how dyslexia should be defined. …”

Cerium oxide for L-band Q-switched pulse laser generation by Mansor, M., Zainol Abidin, N.H., Ng, E.K., Garg, A.K., Liew, J.Y.C., Alresheedi, M.T., Mahdi, M.A.

“…The Q-switched fiber laser remained stable over a 45-minute observation time at 153.20 mW pump power. …”
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The role of growth factor receptor bound protein 2 (GRB2) in gain of function of mutant p53. by Lau, Sok Ting.

“…In this study, GRB2, a binding partner of mutant p53 was explored to uncover its role in mutant p53 “gain-of-function”. …”
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Using an established restaurant brand to launch a new product : a case study on JUMBO retail pack by Boon, Ting Pei, Heng, Yan Ting, Tan, Yanlin

“…A competitive analysis was conducted on the JUMBO retail pack and various other close competitors, which eventually yielded that the JUMBO retail pack triumphs over the other brands according to both taste and ease of cooking.…”
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Extended features based random vector functional link network for classification problem by Malik, Ashwani Kumar, Ganaie, M. A., Tanveer, M., Suganthan, Ponnuthurai Nagaratnam

“…Random vector functional link (RVFL) network has been successfully employed in diverse domains such as computer vision and machine learning, due to its universal approximation capability. …”
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Modeling of an intelligent pressure sensor using functional link artificial neural networks by Patra, Jagdish Chandra, Van den Bos, Adriaan

“…The proposed functional link ANN (FLANN) is a computationally efficient nonlinear network and is capable of complex nonlinear mapping between its input and output pattern space. …”
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Identifying stakeholders in the land use management process and related critical factors in ASEAN by Tulus Tambunan

“…Consequently, land conflicts – disagreements and disputes over access to, control and use of land or natural resources – have emerged. …”
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Advanced nanostructured materials : wide-band-gap oxides based magnetic semiconductors by Xing, Guozhong

“…Nanomaterials and Spintronics are focuses of research over the past ten years. The conjunction of electron spin with the charge manipulation in the semiconductor could lead to a whole new era in information technology, called semiconductor spintronics. …”
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Long-term mindfulness meditation increases occurrence of sensory and attention brain states by Panitz, DY, Mendelsohn, A, Cabral, J, Berkovich-Ohana, A

“…Interest has been growing in the use of mindfulness meditation (MM) as a therapeutic practice, as accumulating evidence highlights its potential to effectively address a range of mental conditions. …”

Blimp-1 and c-Maf regulate immune gene networks to protect against distinct pathways of pathobiont-induced colitis by Alvarez-Martinez, M, Cox, LS, Pearson, CF, Branchett, WJ, Chakravarty, P, Wu, X, Slawinski, H, Al-Dibouni, A, Samelis, VA, Gabryšová, L, Priestnall, SL, Suárez-Bonnet, A, Mikolajczak, A, Briscoe, J, Powrie, F, O'Garra, A

“…Here, we use single-cell RNA sequencing of colon lamina propria leukocytes (LPLs) along with RNA-seq and ATAC-seq of purified CD4⁺ T cells to show that the transcription factors Blimp-1 (encoded by Prdm1) and c-Maf co-dominantly regulate Il10 while negatively regulating proinflammatory cytokines in effector T cells. …”