Improving clinical care of patients in Nipah outbreaks: moving beyond 'compassionate use' by Hassan, MZ, Rojek, A, Olliaro, P, Horby, P

“…Current care relies on supportive measures and the ‘compassionate use’ of unapproved drugs like ribavirin and remdesivir. …”

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data by Murrin, O, Mounier, N, Voller, B, Tata, L, Gallego-Moll, C, Roso-Llorach, A, Carrasco-Ribelles, LA, Fox, C, Allan, LM, Woodward, RM, Liang, X, Valderas, JM, Khalid, S, Dudbridge, F, Lamb, SE, Mancini, M, Farmer, L, Boddy, K, Bowden, J, Melzer, D, Frayling, TM, Masoli, JAH, Pilling, LC, Violán, C, Delgado, J

“…</p> <p><strong>Methods: </strong>We defined chronic, common, and heritable conditions in individuals aged ≥65 years, using two large primary-care databases [CPRD (UK) N = 2,425,014 and SIDIAP (Spain) N = 1,053,640], and estimated heritability using the same definitions in UK Biobank (N = 451,197). …”

CRISPR-enabled point-of-care genotyping for APOL1 genetic risk assessment by Greensmith, Robert, Lape, Isadora T., Riella, Cristian V., Schubert, Alexander J., Metzger, Jakob J., Dighe, Anand S., Tan, Xiao, Hemmer, Bernhard, Rau, Josefine, Wendlinger, Sarah, Diederich, Nora, Schütz, Anja, Riella, Leonardo V.

“…However, current methods, relying on hybridization or sequencing, are unsuitable for point-of-care settings. In contrast, CRISPR-based-diagnostics offer high sensitivity and specificity for point-of-care applications. …”
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Creation of a world class manufacturing system in a health-care company by Tay, Albert Kim Chuan.

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Automated mean arterial pressure control for postoperative patients in intensive care conditions by Ma, Jie

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Sharing is caring? International Society for Pharmacoepidemiology review and recommendations for sharing programming code by Tazare, J, Wang, SV, Gini, R, Prieto Alhambra, D, Arlett, P, Morales Leaver, DR, Morton, C, Logie, J, Popovic, J, Donegan, K, Schneeweiss, S, Douglas, I, Schultze, A

Gaps In Primary Care And Health System Performance In Six Latin American And Caribbean Countries by Macinko, James, Guanais, Frederico C., Mullachery, Pricila, Jimenez, Geronimo

Subjects: “…Organization and Delivery of Care…”
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Comparing the prevalence of multimorbidity using different operational definitions in primary care in Singapore based on a cross-sectional study using retrospective, large administrative data by Lee, Janis Yi An, Xie, Ying, Lee, Sabrina Poay Sian, Lee, Eng Sing

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Multiple description coded video streaming in peer-to-peer networks by Li, Xue Jun., Xu, Yuanyuan., Zhu, Ce., Zeng, Wenjun.

“…It is known that in a peer-to-peer (P2P) network a peer node serves as both a receiver and a supplier, which enables uploading bandwidth of peer nodes to be utilized efficiently while relieving burden of the server node. …”
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Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in the UK PANORAMIC trial by Png, ME, Harris, V, Grabey, J, Hart, ND, Jani, BD, Butler, D, Carson-Stevens, A, Coates, M, Cureton, L, Dobson, M, Dorward, J, Evans, P, Francis, N, Gbinigie, OA, Hayward, G, Holmes, J, Hood, K, Khoo, S, Ahmed, H, Lown, M, McKenna, M, Mort, S, Nguyen-Van-Tam, J, Rahman, N, Richards, DB, Thomas, N, van Hecke, O, Hobbs, FR, Little, P, Yu, L-M, Butler, CC, Petrou, S

“…<p><strong> Conclusion </p></strong>At the current cost of £513 per course, molnupiravir is unlikely to be cost-effective relative to usual care over a 6-month time horizon among mainly vaccinated patients with COVID-19 at increased risk of adverse outcomes, except those aged ≥75 years.…”

Nintendo Wii as an intervention : improving the well-being of elderly in long-term care facilities. by Koay, Jing Li., Ng, Janissa Sihui., Wong, Gladys Li Chieh.

“…A six week-long intervention was held in SASCO Senior Citizens’ Home, a long-term care facility in Singapore. 45 residents aged between 56 and 92 years old took part in the study. …”
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Emergency care knowledge, utilization, and barriers in Northern Tanzania: A community-based survey by Shayo, F, Zaccheus, GG, Sakita, F, Hernandes, TR, Vissoci, JRN, Gordee, A, Kuchibhatla, M, Kiremeji, M, Minja, L, Mmbaga, BT, Staton, CA, Keating, EM, Joiner, AP

“…Background: Emergency care systems are critical to improving care for time-sensitive emergency conditions. …”

Rethinking how development assistance for health can catalyse progress on primary health care by Kasper, T, Yamey, G, Dwyer, S, McDade, KK, Lidén, J, Lüdemann, C, Diab, MM, Ogbuoji, O, Poodla, P, Schrade, C, Thoumi, A, Zimmerman, A, Assefa, Y, Allen, LN, Basinga, P, Garcia, PJ, Jackson, D, Mwanyika, H, Nugent, R, Ofosu, A, Rawaf, S, Reddy, KS, Settle, D, Tritter, B, Benn, C

“…The second is the educational, training, and supervisory systems needed to improve the quality of care. We estimate that with an additional international investment of between US<span>$</span>1.87 billion in a low-investment scenario and <span>$</span>3.85 billion in a high-investment scenario annually over the next 3 years, the international community could support the scale-up of this evidence-based package of investments in the 59 low-income and middle-income countries that are eligible for external financing from the World Bank Group's International Development Association.…”

The novel application of the lightning process to treat long COVID in primary care: case report by Finch, Fiona, Parker, Phil, Nollett, C., Burns, S.

“…Little evidence exists regarding how this chronic condition should be treated, but guidelines suggest for most people it can be managed symptomatically in primary care. The Lightning Process is a trademarked positive psychology focused self-management programme which has shown to be effective in reducing fatigue and accompanying symptoms in other chronic conditions including Chronic Fatigue Syndrome/Myalgic Encephalomyelitis. …”
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A feed-centric hypoglycaemia pathway ensures appropriate care escalation in at-risk infants by Chandran, Suresh, Siew, Jia Xuan, Rajadurai, Victor Samuel, Lim, Rachel Wei Shan, Chua, Mei Chien, Yap, Fabian

“…FCP involves skin-to-skin care, early breast feeding, checking glucose at 2 hours and use of buccal glucose. …”
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Knowledge and attitude regarding care of age-related hearing loss among nurses in HUSM by Rusli, Intan Yusrina

“…However, research on age-related hearing loss remains limited, highlighting the importance of conducting comprehensive studies to improve early identification, intervention, and overall management in elderly care. This study aims to determine knowledge and attitude regarding care of age-related hearing loss among nurses in HUSM and examine the correlation between knowledge and attitude regarding care of age-related hearing loss among nurses in HUSM. …”
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Care, competency, or honesty? Framing emergency preparedness messages and risks for nuclear energy in Singapore by Ho, Shirley S., Kim, Nuri, Looi, Jiemin, Leong, Alisius D.

“…Messages centered on care influenced participants’ trust in government the most. …”
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Mortality forecasts for long-term care subpopulations with longevity risk : a bayesian approach by Kogure, Atsuyuki, Fushimi, Takahiro, Kamiya, Shinichi

“…This article aims to propose a new Bayesian methodology to forecast mortality rates of long-term care (LTC) subpopulations with longevity risk. A major obstacle to developing such a method is lack of data on the number of deaths in LTC subpopulations, which would prevent us from using conventional mortality models such as the Lee-Carter model. …”
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Tea trolley teaching in critical care: integrating evidence-based practice with library services by McGivern, H, Bridge, S, Sutherland, S, Reynolds, E, Ede, J

“…Our evaluation highlights the value of this combined intervention of teaching research skills to upskill staff working in our intensive care units. This paper describes a scalable model of critical care bedside education that integrates library-focused teaching to upskill nurses in some of the prerequisite skills needed for evidence-based practice (EBP).…”

Analysis of peer-to-peer car sharing data in major Chinese cities by Hang, Zhi Cheng

“…However, research insights on peer-to-peer car sharing activities have only been largely limited to the European region. …”
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