Layer-by-Layer Nanoparticles for Cytokine Delivery by Pires, Ivan S.

“…In this thesis, we address some aspects of NPs that have limited their clinical utility including manufacturing, control over self-assembly, and mechanistic understanding of their interactions in biological environments The focus here was on using liposomal LbL-NPs coated with a bilayer of poly-L-arginine (PLR) and poly-L-glutamate (PLE). …”
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Optimized core design of a supercritical carbon dioxide-cooled fast reactor by Handwerk, Christopher S. (Christopher Stanley), 1974-

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Brain computer interface for post-stroke motor rehabilitation by Mane, Ravikiran Tanaji

“…Moving ahead, we analyze the classification performance of proposed and baseline deep learning architectures and traditional machine learning methods for MI detection in 25 chronic stroke patients undergoing three different BCI-based motor rehabilitation interventions for 2/4 weeks. Here, we show that in subject-specific multi-session classification settings, the proposed method of FBCNet can learn highly generalizable discriminative features which remain valid during inter-session classification. …”
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A Brewster route to Cherenkov detectors by Lin, Xiao, Hu, Hao, Easo, Sajan, Yang, Yi, Shen, Yichen, Yin, Kezhen, Blago, Michele Piero, Kaminer, Ido, Zhang, Baile, Chen, Hongsheng, Joannopoulos, John, Soljačić, Marin, Luo, Yu

“…Overcoming this fundamental material limit is important for future particle detectors yet remains a long-standing challenge. Here, we propose a different paradigm for Cherenkov detectors that utilizes the broadband angular filter made from stacks of variable onedimensional photonic crystals. …”
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Mitofusins Mfn1 and Mfn2 are required to preserve glucose- but not incretin-stimulated β-cell connectivity and insulin secretion by Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Yong, Fiona Su Wern, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.

“…Whether mitofusin gene expression, and hence, mitochondrial network integrity, is important for glucose or incretin signaling has not previously been explored. Here, we generated mice with β-cell-selective, adult-restricted deletion knock-out (dKO) of the mitofusin genes Mfn1 and Mfn2 (βMfn1/2 dKO). βMfn1/2-dKO mice displayed elevated fed and fasted glycemia and a more than fivefold decrease in plasma insulin. …”
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A wireless and battery-free wound infection sensor based on DNA hydrogel by Xiong, Ze, Achavananthadith, Sippanat, Lian, Sophie, Madden, Leigh Edward, Ong, Zi Xin, Chua, Wisely, Kalidasan, Viveka, Li, Zhipeng, Liu, Zhu, Singh, Priti, Yang, Haitao, Heussler, Sascha P., Kalaiselvi, S. M. P., Breese, Mark B. H., Yao, Haicheng, Gao, Yuji, Sanmugam, Kavitha, Tee, Benjamin C. K., Chen, Po-Yen, Loke, Weiqiang, Lim, Chwee Teck, Chiang, Grace Shu Hui, Tan, Boon Yeow, Li, Hao, Becker, David Laurence, Ho, John S.

“…Wound infections represent a major clinical challenge in which timely detection is critical for effective interventions, but this is currently hindered by the lack of a monitoring technology that can interface with wounds, detect pathogenic bacteria, and wirelessly transmit data. Here, we report a flexible, wireless, and battery-free sensor that provides smartphone-based detection of wound infection using a bacteria-responsive DNA hydrogel. …”
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Synthesis of densely functionalized pyrroles from unprotected carbohydrates by Xia, Mengxin

“…In Chapter Five, the reaction between α-hydroxyketones, oxoacetonitriles, and primary amines selectively gave N-substituted 2,3,5-functionalized 3-cyanopyrroles in up to 90% isolated yields. Here again, the reaction demonstrated broad substrate scope, proceeded under mild conditions (AcOH as a catalyst, EtOH, 70 oC, 3 h) and worked also on a large gram scale. …”
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Weakly confined organic–inorganic halide perovskite quantum dots as high-purity room-temperature single photon sources by Wang, Bo, Lim, Melvin Jia Wei, Loh, Siow Mean, Mayengbam, Rishikanta, Ye, Senyun, Feng, Minjun, He, Huajun, Liang, Xiao, Cai, Rui, Zhang, Qiannan, Kwek, Leong Chuan, Demir, Hilmi Volkan, Mhaisalkar, Subodh Gautam, Blundell, Steven A., Sum, Tze Chien

“…Achieving high SP purity and blinking mitigation simultaneously remains a significant challenge. Here, we transcend this limitation with room-temperature synthesized weakly-confined hybrid organic–inorganic perovskite (HOIP) QDs. …”
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High-quality semiconductor fibres via mechanical design by Wang, Zhixun, Wang, Zhe, Li, Dong, Yang, Chunlei, Zhang, Qichong, Chen, Ming, Gao, Huajian, Wei, Lei

“…However, owing to stress development and capillary instability in the high-yield fibre thermal drawing, both cracks and deformations in the semiconductor cores considerably affect the performance of these fibres. Here we report a mechanical design to achieve ultralong, fracture-free and perturbation-free semiconductor fibres, guided by a study on stress development and capillary instability at three stages of the fibre formation: the viscous flow, the core crystallization and the subsequent cooling stage. …”
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Genome-wide transcriptome profiling reveals molecular response pathways of Trichoderma harzianum in response to salt stress by Yang, Qihong, Mao, Zhenchuan, Hao, Yali, Zheng, Shijie, Zhao, Jianlong, Li, Yan, Yang, Yuhong, Xie, Bingyan, Ling, Jian, Li, Yanlin

“…The aim of this study was to investigate the molecular response of T. harzianum to salt stress at the whole-genome level. Here, we present a 44.47 Mb near-complete genome assembly of the T. harzianum qt40003 strain for the first time, which was assembled de novo with 7.59 Gb Nanopore sequencing long reads (~170-fold) and 5.2 Gb Illumina short reads (~116-fold). …”
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Structure and interaction of telomeric and telomerase RNA G-quadruplexes. by Martadinata, Herry.

“…Protein hnRNP A1/UP1 were reported to interact with telomeric DNA and TERRA in vivo. hnRNPA A1/UP1 were previously shown to unfold DNA G-quadruplexes from various sequences in vitro. Here we present that protein UP1 binds and unfolds both telomeric DNA and RNA G-quadruplexes. …”
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Harmonized co-existence with robust interference management in femto-macro cellular architectures by Ponnu Jacob

“…Hence each femtocell is embedded with a cognitive capability by means of a radio resource allocation algorithm called Cross-Polarized Complementary Frequency Allocation strategy (CPCFA) which enables it to select its own operational frequency. Here it exploits both frequency and polarization diversity by incorporating reverse frequency allocation within an orthogonally polarized transmission network to maintain its interference to the macrocell user under a pre-determined threshold. …”
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Colloidal quantum dot light-emitting diode architectures for high performance by Leck, Kheng Swee

“…Adding HTL at the electron side limits excess electrons to be injected into the QD layer, resulting in better charge balance. Here an improvement in the device performance of over five-folds was obtained with the proposed device architecture in comparison to the reference device in which the QD layer is deposited between the HTL and the ETL. …”
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Synaptic plasticity in VLSI : a floating-gate approach by Gopalakrishnan, Roshan

“…Compared to the previous work, here we propose a method to localize the effect of potentiation and depression on a FG synapse. …”
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Evolutionary explanations and the debunking of moral beliefs by Cofnas, N

“…A recent study purports to support Westermarck's account by showing that unrelated children raised in the same peer groups on kibbutzim feel sexual aversion toward each other and morally oppose third-party intra-peer-group sex, but this study has been misinterpreted. …”

Biogeochemical cycling and environmental footprints of peatland-derived organic carbon in the coastal ocean in Southeast Asia by Zhou, Yongli

“…The majority of this terrigenous DOC flux enters the Sunda Shelf Sea, where the terrigenous DOC has a relatively long residence time of 1–2 years. Here, we studied the composition, degradation, and environmental footprints of the terrigenous DOC derived from Southeast Asian peatlands in the rivers, estuaries, and the Sunda Shelf Sea. …”
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Towards haptic intelligence in robots by learning from demonstration by Turlapati Sri Harsha

“…Specifically, the contribution here is the viewing of triangular meshes of objects, i.e., the internal model extracted from their 3D scans, not only as a source of geometric information, but also of haptic feedback. …”
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Ultrastrong exciton-plasmon couplings in WS2 multilayers synthesized with a random multi-singular metasurface at room temperature by Wu, Tingting, Wang, Chongwu, Hu, Guangwei, Wang, Zhixun, Zhao, Jiaxin, Wang, Zhe, Chaykun, Ksenia, Liu, Lin, Chen, Mengxiao, Li, Dong, Zhu, Song, Xiong, Qihua, Shen, Zexiang, Gao, Huajian, Garcia-Vidal, Francisco J., Wei, Lei, Wang, Qi Jie, Luo, Yu

“…Boosting their interaction with light is vital for practical applications, especially in the quantum regime where ultrastrong coupling is highly demanded but not yet realized. Here we report ultrastrong exciton-plasmon coupling at room temperature in tungsten disulfide (WS2) layers loaded with a random multi-singular plasmonic metasurface deposited on a flexible polymer substrate. …”
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Reduced semiconductor energy conversion systems. by Zhang, Lei.

“…The term "series-shunt" is used here for representing any system with two sets of three-phase ac terminals. …”
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Disorder–property relationships in magnetic and pseudospin framework materials by Bulled, J

“…Since these results are for thermodynamic variables, they are applicable to a range of quasi–one dimensional materials involving Ising pseudospins beyond the particular family studied here.</p> <br> <p>The series [C(NH₂)₃]Mn(_{1−<em>x</em>}) [Fe_{2<em>x</em>/3}□_<em>x</em>/3](HCOO)₃ is investigated, in which the B–site of the perovskite structure is occupied by Mn²⁺, Fe³⁺ and vacancies (denoted □). …”