Views and uses of sepsis / deterioration digital alerts in NHS Trusts in England: a qualitative study with healthcare professionals by Lazzarino, R, Borek, AJ, Honeyford, K, Welch, J, Brent, AJ, Kinderlerer, A, Cook, G, Patil, S, Gordon, A, Glampson, B, Goodman, P, Ghazal, P, Daniels, R, Costelloe, CE, Tonkin-Crine, S

“…To support rapid sepsis diagnosis and treatment, screening tools have been embedded into hospital digital systems to appear as digital alerts. …”

Identification of novel interactions between MicroRNAs and pattern-recognition receptor signalling in dentritic cells by Pichulik, T

“…Recent evidence has suggested that PRR signalling regulates the expression of microRNAs (miRNAs), important post-transcriptional regulators of gene expression, which have been shown to fine-tune innate immune responses.</p> <p>This thesis describes the discovery of miR-650, a novel PRR-responsive miRNA that is down regulated in monocyte-derived dendritic cells (DCs) on PRR stimulation. …”

Indicators of global climate change 2022: annual update of large-scale indicators of the state of the climate system and human influence by Forster, PM, Smith, CJ, Walsh, T, Lamb, WF, Lamboll, R, Hauser, M, Ribes, A, Rosen, D, Gillett, N, Palmer, MD, Rogelj, J, von Schuckmann, K, Seneviratne, SI, Trewin, B, Zhang, X, Allen, M, Andrew, R, Birt, A, Borger, A, Boyer, T, Broersma, JA, Cheng, L, Dentener, F, Friedlingstein, P, Gutiérrez, JM, Gütschow, J, Hall, B, Ishii, M, Jenkins, S, Lan, X, Lee, J-Y, Morice, C, Kadow, C, Kennedy, J, Killick, R, Minx, JC, Naik, V, Peters, GP, Pirani, A, Pongratz, J, Schleussner, C-F, Szopa, S, Thorne, P, Rohde, R, Rojas Corradi, M, Schumacher, D, Vose, R, Zickfeld, K, Masson-Delmotte, V, Zhai, P

“…Over the 2013&ndash;2022 period, human-induced warming has been increasing at an unprecedented rate of over 0.2&thinsp;^∘C per decade. …”

PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder by Wang, L

“…However, no evidence for DNA replication defects has been found in these patient-derived cells. The aim of this thesis was to determine cellular pathways that are affected by the S228I alteration and to uncover mechanisms by which PCNAS^228I cells tolerate the perturbed PCNA interactions in specific pathways. …”

Large-scale profiling of antibody reactivity to glycolipids in patients with Guillain-Barré syndrome by Thomma, RCM, Halstead, SK, de Koning, LC, Fehmi, J, Rinaldi, S, IGOS consortium

“…Extensive research into clinical associations of individual anti-ganglioside antibody specificities has been performed. Recent research has highlighted glycolipid complexes, glycolipid combinations that may alter antibody binding, as targets. …”

PandoraHearts : Caucus Race, by Shinobu Wakamiya, author 655895, Jun Mochizuki, illustrator 655896

“…Within these pages, four fairy tales unfold, each peering into one of the houses of the four great dukedoms: Vessalius, Rainsworth, Barma, and Nightray. …”
Get full text

Cosystolic Expansion of Sheaves on Posets with Applications to Good 2-Query Locally Testable Codes and Lifted Codes by First, Uriya A., Kaufman, Tali

Get full text

Modeling and Implementation of the U.S. Hydrogen Production Tax Credit by Giovanniello, Michael A.

“…Following the passage of the IRA, there has been a vigorous debate focusing primarily on the time-matching requirements — that is, the period over which electricity use must match production from contracted generators — for grid-connected H2 production to receive the PTC. …”
Get full text
Get full text

The development and application of mass-spectrometry-based tools to monitor proteome remodeling in microbes by Telusma, Bertina

“…Understanding the balance of these contributions has historically been challenging. As such, there is a need for approaches that can quantitatively resolve the contributions of protein synthesis and protein degradation pathways in a wide array of cellular and environmental contexts. …”
Get full text

The Cognitive Underpinnings of Legal Complexity by Martínez, Eric

“…Although principles of communicative efficiency and legal doctrine dictate that laws be comprehensible to the common world, legal documents have long been attested to be incomprehensible to those who are required to comply with them (i.e. everyone). …”
Get full text

Shifting Paradigms: Data-Centric Approach for Marine Statics Correction using Symmetric Autoencoding by Kanniah, Brindha

“…The traditional workflow for correcting marine statics has been based on a model-centric paradigm. This paradigm involves a series of transformations between non-commensurate spaces: first, inversion from seismic data space to velocity model space and second, forward modeling from velocity model space to seismic data space. …”
Get full text
Get full text

Investigating Interventions in Fine-grained Contexts for Habit Formation by Khan, Mina

“…Fine-grained specific contexts are commonly used in habit formation, but interventions in automatically-detected fine-grained contexts have rarely been explored for habit formation. We investigate habit-formation using interventions in fine-grained mobile, physical-world and digital, computer-based contexts, making three key contributions for each: a survey to identify behavior change needs, a prototype system designed to deliver fine-grained context-specific interventions, and a study to investigate habit-formation using interventions in fine-grained contexts, compared to interventions in less fine-grained contexts. …”
Get full text

Quantum mechanical theory of dynamic nuclear polarization in solid dielectrics by Hu, Kan-Nian, Debelouchina, Galia Tzvetanova, Griffin, Robert Guy, Smith, Albert A.

“…Historically these mechanisms have been discussed theoretically using thermodynamic parameters and average spin interactions. …”
Get full text
Get full text

Effects of electromagnetic field on proliferation, differentiation, and mineralization of MC3T3 cells by Teoh, Swee-Hin, Suryani, Luvita, Too, Jian Hui, Hassanbhai, Ammar Mansoor, Wen, Feng, Lin, Daryl Jimian, Yu, Na

“…Pulsed electromagnetic fields (PEMFs) have been documented to promote bone fracture healing in nonunions and to enhance the maturation of osteoblastic cell, which is the key element in bone tissues. …”
Get full text
Get full text

Exploring the utility of silane cross-linkers for synthesis of superhydrophobic antibacterial fabrics by Agrawal, Neha

“…Metal-oxide nanoparticles have been employed to offer antibacterial activity and nanoscale roughness, essential to achieve superhydrophobicity and antibacterial functionality on the fabric. …”
Get full text
Get full text

Liposomal nanotherapy for treatment of atherosclerosis : passive versus active targeting by Darwitan, Anastasia

“…Inflammation is the underlying pathological process of atherosclerosis, the major cause of most CVD, but has not been adequately addressed. Additionally, the increasing age trend of general population will present increasing incidence with individual’s unique and complex coronary anatomy with high-risk comorbidities. …”
Get full text

Creative ageing in Singapore : a population study on participatory arts engagement and wellbeing among adults aged 50 and above by Ma, Stephanie Hilary Xinyi

“…While anecdotal and increasing empirical evidence suggest that participatory arts can play an essential role in supporting a healthy ageing population, much less research has been conducted in Asian societies. Furthermore, despite growing interest in arts programmes for older adults in Singapore, little is known about the patterns and impact of arts engagement among local seniors. …”
Get full text

Feature extraction from EEG signals and regularization for brain-computer interface by Mishuhina, Vasilisa

“…To enhance the performance of CSP, different variations of this method have been proposed in literature. However, each approach has its own limitations and does not perform well for different subjects and datasets. …”
Get full text

Shear-flow characteristics of rock fractures and implications for injection-induced seismicity by Ji, Yinlin

“…Hydraulic stimulation has been employed to enhance the permeability of geothermal reservoirs and to maintain the productivity of renewable heat. …”
Get full text

Doubly coated, organic–inorganic paraffin phase change materials : zinc oxide coating of hermetically encapsulated paraffins by Mikhaylov, Alexey A., Medvedev, Alexander G., Grishanov, Dmitry A., Sladkevich, Sergey, Xu, Jason Zhichuan, Sakharov, Konstantin A., Prikhodchenko, Petr V., Lev, Ovadia

Get full text