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    Near-Infrared Fluorescent Molecular Probe for Sensitive Imaging of Keloid by Miao, Qingqing, Yeo, David Chenloong, Wiraja, Christian, Zhang, Jianjian, Ning, Xiaoyu, Xu, Chenjie, Pu, Kanyi

    Published 2018
    “…As keloid cells have high expression levels of fibroblast activation protein-alpha (FAPα), the probe (FNP1) is designed to have a caged NIR dye and a FAPα-cleavable peptide substrate linked by a self-immolative segment. FNP1 can quickly and specifically turn on its fluorescence at 710 nm by 45-fold in the presence of FAPα, allowing it to effectively recognize keloid cells from normal skin cells. …”
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    Journal Article
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