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pin » ping (Expand Search), spin (Expand Search)
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Near-Infrared Fluorescent Molecular Probe for Sensitive Imaging of Keloid
Published 2018“…As keloid cells have high expression levels of fibroblast activation protein-alpha (FAPα), the probe (FNP1) is designed to have a caged NIR dye and a FAPα-cleavable peptide substrate linked by a self-immolative segment. FNP1 can quickly and specifically turn on its fluorescence at 710 nm by 45-fold in the presence of FAPα, allowing it to effectively recognize keloid cells from normal skin cells. …”
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Journal Article -
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