Analysis of subtelomeric virulence gene families in Plasmodium falciparum by comparative transcriptional profiling by Witmer, Kathrin, Schmid, Christoph D., Brancucci, Nicolas M. B., Luah, Yen-Hoon, Preiser, Peter Rainer, Bozdech, Zbynek, Voss, Till S.

“…Here, we analysed promoters of upsA, upsB and upsC var, rifA1-type rif, stevor, phist and pfmc-2tm genes and investigated their role in endogenous gene transcription by comparative genome-wide expression profiling of transgenic parasite lines. We find that the three major var promoter types are functionally equal and play an essential role in singular gene choice. …”
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A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system by Shen, Yunbing, Jiang, Long, Iyer, Vaishnavi Srinivasan, Raposo, Bruno, Dubnovitsky, Anatoly, Boddul, Sanjaykumar V., Kasza, Zsolt, Wermeling, Fredrik

“…Here, we present a rapid and universal experimental approach to functionally analyze a CRISPR-targeted cell population that does not involve generating clonal lines. As a simple readout, we leverage the CRISPR-induced genetic heterogeneity and use sequencing to identify how different genotypes are enriched or depleted in relation to the studied cellular behavior or phenotype. …”
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Elucidating the size-dependency of in vitro digested polystyrene microplastics on human intestinal cells health and function by Ma, Yiyuan, Koh, Cheryl Jie Yan, Lim, Hong Kit, Shi, Pujiang, Tay, Chor Yong

“…Herein, the potential deleterious biological effects of pristine and in vitro digested polystyrene (PS) MPs of varying sizes (i.e., 0.1, 1, and 10 µm) are systematically examined over a wide concentration range of 25–400 µg mL−1 on two human intestinal cell lines, namely Caco-2 and NCM 460. Specifically, significant internalization of 0.1 and 1 µm PS -MPs have been observed in both cell types 24 h postexposure. …”
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Label-free assessment of differentiation efficiency in iPSC-derived spinal cord progenitor cells via Magnetic Resonance Relaxometry (MRR) by Tan, Jerome Zu Yao, Chen, Jiahui, Roxby, Daniel, Chooi, Wai Hon, Nguyen, Tan Dai, Ng, Shi-Yan, Chew, Sing Yian, Han, Jongyoon

“…In this study, human iPSCs derived from Cord Lining Endothelial cells were differentiated into Spinal-cord Progenitor Cells (SCPCs) through a 10-day process. …”
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Flexible integrated sensor with asymmetric structure for simultaneously 3D tactile and thermal sensing by Wang, Yongqing, Sun, Kun, Zhang, Qisheng, Yu, Samson Shenglong, Han, Boon Siew, Wang, Jianpeng, Zhao, Mingyan, Meng, Xianglin, Chen, Sicheng, Zheng, Yuanjin

“…The resistive thermal sensors are fabricated with serpentine lines and possess stable heat-sensing performance (165 mV/°C) under shape deformation conditions. …”
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Luteolin restricts dengue virus replication through inhibition of the proprotein convertase furin by Peng, Minhua, Watanabe, Satoru, Chan, Kitti Wing Ki, He, Qiuyan, Zhao, Ya, Zhang, Zhongde, Lai, Xiaoping, Luo, Dahai, Vasudevan, Subhash G., Li, Geng

“…In addition, ADE-mediated dengue virus infection of human cell lines and primary PBMCs was inhibited. In a time-of-drug-addition study, luteolin was found to reduce infectious virus particle formation, but not viral RNA synthesis, in Huh-7 cells. …”
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Mythical heroines : the appropriation of myth in reconstructing female identities in ethnic American literature by Goh, I-Mei.

“…The three literary texts being investigated along these lines are Maxine Hong Kingston’s The Woman Warrior, Bharati Mukherjee’s Jasmine and Toni Morrison’s Beloved. …”
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Determinants of Expatriate Manager Failures in the International Assignment by Mansor, Mohd Fitri, Abd Hamid, Nurzawani, Kamil, Syahida, Abu, Noor Hidayah

“…The international assignment requires an organization send their staff abroad for high potential career development, to coordinate global lines of business, transfer the organization knowledge in abroad, expand into new markets worldwide and also manage an international subsidiary. …”
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Power system modeling and simulation by Luo, Yishi

“…The dissertation initially develops a equivalent model under steady state and dynamic state with implement of parameters from PES-TR19, then the power flow calculation and dynamic contingency analysis including overloading, underloading, tripping of tie lines and changes in load composition are proceeded, finally, the white paper emphasizes on analyzing the rotor angle, frequency, voltage stability of some elements including generators, bus bars in Nordic-74 test system. …”
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Search in location based social network by Lew, Stephanie Yin Hui.

“…The project can be potentially expanded to support other kinds of geospatial shapes such as polygons or lines, apart of venue points and also other types of spatial querying such as collective or relevant region querying that returns relevant groups of spatial objects.…”
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Website performance study by Qian, Lei

“…Taking into consideration customers’ high expectation of web application performance and potential negative consequences brought by poor performance, this report offers a comprehensive range of solutions to enhance web performance so as to perfect end-user experiences and further boost business bottom lines where applicable. The experiment was carried out on the self-built blog web application. …”
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Primary intestinal epithelial cell response to Helicobacter hepaticus in an ex vivo setting by Alrawaf, S

“…<p>Epithelial cells lining the intestinal mucosa play a critical role in mucosal immune homeostasis. …”

“Or they could just not use it?”: the dilemma of AI disclosure for audience trust in news by Toff, B, Simon, FM

“…We test whether audiences in the United States, where trust is particularly polarized along partisan lines, perceive news labeled as AI-generated as more or less trustworthy. …”

Evolutionary origin of the chordate nervous system revealed by amphioxus developmental trajectories by Dai, Y, Zhong, Y, Liu, H, Pan, R, Yuan, L, Du, J, Li, M, Wang, X, Shi, C, Liu, G, Zhu, P, Shimeld, S, Zhou, X, Li, G

“…We characterized cell specification at the mechanistic level and generated mutant lines to examine the function of five key transcription factors involved in neural specification. …”

新移民的跨国实践和离散论述 ：孙侠(铃铛)个案研究 = Transnational practice and diasporic discourses of new immigrant : a case study on Sun Xia (Ling Dang) by Sun, Guizi

“…Instead, she lives a double life through transnational links between Singapore and China. She started her transnational journeys in 2004 as an international student in Singapore. …”
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KnitworkVR: Dual-reality Experience through Distributed Sensor-Actuator Networks in the Living Knitwork Pavilion by Wicaksono, Irmandy, Blanchard, Lancelot, Chin, Sam, Colon, Cristian, Paradiso, Joseph

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Snooping Underwater Communications via Low-Cost mmWave Radars by Mollahosseini, Poorya, Afzal, Sayed Saad, Adib, Fadel, Ghasempour, Yasaman

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The acquisition of English and Mandarin by a Singaporean child in a trilingual home by Teo, Jennifer Lay Heong.

“…Results indicate that: (1)the absence of tense and number markers in the English data was due to the variety of Singapore Colloquial English the child was exposed to in his environment; (2)the use of pragmatic particles and the lack of clear developmental pattern in the English interrogatives were linked to the Singapore Colloquial English usage in the input; (3)the English-language acquisition pattern shows a similar pattern as those in other comparable studies done in Singapore; (4)the order of the grammatical morphemes in the Mandarin data follows the similar pattern as other monolingual children reported on; (5)code-switching and code-mixing were directly affected by social factors: interlocutor, norm of the speech situation and his language dominance; (6)code-switching also occurs for many reasons related to language use; and (7)the child language development has been affected by the varying amount of input. …”
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Protein profile in cells exposed to non-thermal radiofrequency-field by Chai, Richie

“…There were visible changes in relative abundance of Histone 2A and Histone 4, which can be linked to possible DNA damages. However, there was no evidence of changed in protein level especially in metabolic proteins. …”
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The search for inhibitors of the quorum sensing receptor of pseudomonas aeruginosa. by Chua, Jenna.

“…Its persistence in disease can be linked to its readiness to form biofilms and release harmful virulence factors at the population level through inter-cell bacterial communication or quorum sensing (QS). …”
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