Evaluating the effect of rapamycin treatment in Alzheimer’s disease and aging using in vivo imaging: the ERAP phase IIa clinical study protocol by Svensson, Jonas E., Bolin, Martin, Thor, Daniel, Williams, Pete A., Brautaset, Rune, Carlsson, Marcus, Sörensson, Peder, Marlevi, David, Spin-Neto, Rubens, Probst, Monika, Hagman, Göran, Morén, Anton Forsberg, Kivipelto, Miia, Plavén-Sigray, Pontus

“…Methods ERAP is a six-month-long, single-arm, open-label, phase IIa biomarker-driven study evaluating if the drug rapamycin can be repurposed to treat Alzheimer’s disease. …”
Get full text

Delivery of therapeutic carbon monoxide by gas-entrapping materials by Byrne, James D., Gallo, David, Boyce, Hannah, Becker, Sarah L., Kezar, Kristi M., Cotoia, Alicia T., Feig, Vivian R., Lopes, Aaron, Csizmadia, Eva, Longhi, Maria Serena, Lee, Jung Seung, Kim, Hyunjoon, Wentworth, Adam J., Shankar, Sidharth, Lee, Ghee Rye, Bi, Jianling, Witt, Emily, Ishida, Keiko, Hayward, Alison, Kuosmanen, Johannes L. P., Jenkins, Josh, Wainer, Jacob, Aragon, Aya, Wong, Kaitlyn, Steiger, Christoph, Jeck, William R., Bosch, Dustin E., Coleman, Mitchell C., Spitz, Douglas R., Tift, Michael, Langer, Robert, Otterbein, Leo E., Traverso, Giovanni

“…Carbon monoxide (CO) has long been considered a toxic gas but is now a recognized bioactive gasotransmitter with potent immunomodulatory effects. …”
Get full text

SNARGs under LWE via Propositional Proofs by Jin, Zhengzhong, Kalai, Yael, Lombardi, Alex, Vaikuntanathan, Vinod

Get full text

Designing Electricity Distribution Network Tariffs for Beneficial Electrification by Turk, Graham

“…In this thesis, we challenge that perception by asking whether well-designed distribution network tariffs can deliver a win-win in the long run, reducing operating costs for EVs and/or CCHPs and average network costs for households that cannot yet afford to electrify. …”
Get full text

Multifunctional Wireless Gut-Brain Neurotechnology by Sahasrabudhe, Atharva

“…This approach produces meters-long continuous fibers that can integrate light sources, electrodes, thermal sensors, and microfluidic channels in a miniature footprint. …”
Get full text

Envisioning Water: Sustainability and Future-Making in Dubai and Los Angeles by Christidi, Nadia

“…Both Dubai and LA are cities that have long been deemed unsustainable, but are aiming to become sustainability leaders. …”
Get full text

In Tension: Computational exploration of the design space of tensile network structures by Burke, Adam T.

“…Tensile network structures are often used to span long distances without intermediate supports and have found applications in art, architecture, and structural engineering due to their physical and visual lightness. …”
Get full text
Get full text

Piezoelectric single crystal based one-dimensional phased array for breast tissue imaging by Du, Wenya

“…Replacing rigid transducers with conformable ultrasound transducer arrays can allow image acquisition on curved body parts, improve image quality, and enable functions such as long-term monitoring. In this thesis, I propose a conformable ultrasound breast patch (cUSBr-Patch) consisting of a one-dimensional (1D) phased array and a nature-inspired patch design, which offers large-area, deep tissue scanning and multi-angle, repeatable breast imaging while avoiding the drawbacks of conventional ultrasound imaging technologies. …”
Get full text

Imaging the initial condition of heavy-ion collisions and nuclear structure across the nuclide chart by Jia, Jiangyong, Giacalone, Giuliano, Bally, Benjamin, Brandenburg, James D., Heinz, Ulrich, Huang, Shengli, Lee, Dean, Lee, Yen-Jie, Loizides, Constantin, Li, Wei, Luzum, Matthew, Nijs, Govert, Noronha-Hostler, Jacquelyn, Ploskon, Mateusz, van der Schee, Wilke, Schenke, Bjoern

“…Originally prepared as input for the long-range plan of U.S. nuclear physics, this white paper reflects the status as of September 2022, with a brief update on developments since then.…”
Get full text

Robust Reinforcement Learning Strategies with Evolving Curriculum for Efficient Bus Operations in Smart Cities by Tang, Yuhan, Qu, Ao, Jiang, Xuan, Mo, Baichuan, Cao, Shangqing, Rodriguez, Joseph, Koutsopoulos, Haris N, Wu, Cathy, Zhao, Jinhua

“…It’s difficult to learn them all together, due to learning complexity, we employ domain knowledge and develop a gradually expanding action space curriculum, enabling agents to learn these strategies incrementally. We incorporate Long Short-Term Memory (LSTM) in our model considering the temporal interrelation among these actions. …”
Get full text

Picophytoplankton of the Northeast U.S. Shelf: Community Composition and Dynamics by Stevens, Bethany Lynn Fowler

“…This thesis uses a combination of long-term monitoring, cruise data, population models, and high-throughput sequencing to investigate the dynamics of picophytoplankton across scales of space and time that are relevant both to the physiology of the individual cells and to the structure of the Northeast U.S. …”
Get full text
Get full text

Mechanical design and analysis of implantable components for a retinal prosthesis by Moss, Joshua D. (Joshua David), 1975-

Get full text

Restoring product focus across the value stream through organizational restructuring by Pasqual, Jeffrey M. (Jeffrey Michael)

Get full text

Threshold estimation models for linear threshold-based influential user mining in social networks by Talukder, Ashis, Tran, Nguyen H., Niyato, Dusit, Park, Gwan Hoon, Hong, Choong Seon, Mohammad Golam Rabiul Alam

Get full text
Get full text

Chromatin laser imaging reveals abnormal nuclear changes for early cancer detection by Chen, Yu-Cheng, Chen, Qiushu, Tan, Xiaotain, Chen, Grace, Bergin, Ingrid, Muhammad Nadeem Aslam, Fan, Xudong

Get full text
Get full text
Get full text

From cellular automata to agent-based models : addressing urban issues by Quek, Wei Liang

“…By proposing a novel combination of serial and parallel expansions, the analytical flow rate shows that optimal efficiencies are achieved via configurations with few (many) lanes of a large (small) number of serial units when the processing time is short (long). The problem of bus bunching can be found in every bus system. …”
Get full text

Human comfort in indoor environment : a review on assessment criteria, data collection and data analysis methods by Song, Ying, Mao, Fubing, Liu, Qing

Get full text

Environmental and human data-driven model based on machine learning for prediction of human comfort by Mao, Fubing, Zhou, Xin, Song, Ying

Get full text

Is Africa’s growing public debt really crowding out private investment? by Mulangu, Francis

“…Third, do African firms rely on commercial banks to support both their working capital expenditures and long-term investment? Moreover, how has this changed over the period during which national debts have been rising? …”
Get full text

An ultrastable lithium metal anode enabled by designed metal fluoride spansules by Yuan, Huadong, Nai, Jianwei, Tian, He, Ju, Zhijin, Zhang, Wenkui, Liu, Yujing, Tao, Xinyong, Lou, David Xiong Wen

“…Here, we design “spansules” made of NaMg(Mn)F3@C core@shell microstructures as the matrix for the LMA, which can offer a long-lasting release of functional ions into the electrolyte. …”
Get full text