A comparison of sodium-glucose co-transporter 2 inhibitor kidney outcome trial participants with a real-world chronic kidney disease primary care population by Forbes, AK, Hinton, W, Feher, MD, Elson, W, Ordóñez-Mena, JM, Joy, M, Fan, X, Banerjee, D, Cole, NI, Munro, N, Whyte, M, Suckling, RJ, Swift, PA, de Lusignan, S

“…Females were under-represented and less likely to be eligible for the trials.</p> <br> <p><strong>Conclusion:</strong> SGLT2 inhibitor kidney outcome trials represent a subgroup of people with CKD at high risk of adverse kidney events. …”

The influence of nicotinic acid adenine dinucleotide phosphate (NAADP) signalling and the significance of the organization of lysosomes in cardiac myocytes by Aston, D

“…</p> <p>Calcium released from the lysosome in response to NAADP action at TPC2 is thought to modulate calcium release from the SR. This process is likely to require a close spatial relationship between these organelles. …”

HLA-DQB1*05 subtypes and not DRB1*10:01 mediates risk in anti-IgLON5 disease by Yogeshwar, SM, Muñiz-Castrillo, S, Sabater, L, Peris-Sempere, V, Mallajosyula, V, Luo, G, Yan, H, Yu, E, Zhang, J, Lin, L, Fagundes Bueno, F, Ji, X, Picard, G, Rogemond, V, Pinto, AL, Heidbreder, A, Höftberger, R, Graus, F, Dalmau, J, Santamaria, J, Iranzo, A, Schreiner, B, Giannoccaro, MP, Liguori, R, Shimohata, T, Kimura, A, Ono, Y, Binks, S, Mariotto, S, Dinoto, A, Bonello, M, Hartmann, CJ, Tambasco, N, Nigro, P, Prüss, H, McKeon, A, Davis, MM, Irani, SR, Honnorat, J, Gaig, C, Finke, C, Mignot, E

“…<p>Anti-IgLON5 disease is a rare and likely underdiagnosed subtype of autoimmune encephalitis. …”

Environmental risk factors for self-harm during imprisonment: a prospective cohort study by Stephenson, T, Harris, I, Armstrong, C, Fazel, S, Short, R, Blackwood, N

“…Findings regarding staff-prisoner ratio and self-harm most likely reflect a reverse causal relationship. Replication in larger cohort studies is required to address the limitations of this pilot study.…”

The impact of social isolation on delayed hospital discharges of older hip fracture patients and associated costs by Landeiro, F, Leal, J, Gray, A

“…Patients who were admitted from an institution were less likely to have delayed discharges (OR 0.2) with 5.5 fewer days of delay. …”

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data by Murrin, O, Mounier, N, Voller, B, Tata, L, Gallego-Moll, C, Roso-Llorach, A, Carrasco-Ribelles, LA, Fox, C, Allan, LM, Woodward, RM, Liang, X, Valderas, JM, Khalid, S, Dudbridge, F, Lamb, SE, Mancini, M, Farmer, L, Boddy, K, Bowden, J, Melzer, D, Frayling, TM, Masoli, JAH, Pilling, LC, Violán, C, Delgado, J

“…Discordance between genetic and primary care data was also observed, e.g., abdominal aortic aneurysm and bladder cancer co-occurred in primary care but were not genetically correlated (Odds-Ratio = 2.23 [2.09:2.37], 𝑅𝑔 = 0.04 [−0.20:0.28]) and schizophrenia and fibromyalgia were less likely to co-occur together in primary care but were positively genetically correlated (OR = 0.84 [0.75:0.94], 𝑅𝑔 = 0.20 [0.11:0.29]).…”

Management and outcomes of thoracic sarcomas - a collaboration between Orthopaedic Oncology and cardiothoracic surgery: seven-year clinical data from a tertiary referral centre by Shamsi, ZA, Paraoan, V, Kim, C, Saifuddin, SR, Cosker, TDA, Whitwell, D, Gibbons, CLMH, Stavroulias, D, DiChiara, F

“…Variability in outcomes and overall survival likely stems from factors such as histological diversity, predominance of high-grade sarcomas, and wide age range at diagnosis. …”

Cytisine versus varenicline for smoking cessation in a primary care setting: a randomized non-inferiority trial by Oreskovic, T, Percac-Lima, S, Ashburner, JM, Tiljak, H, Rifel, J, Klemenc Ketiš, Z, Oreskovic, S

“…Given the much lower cost of cytisine treatment, its lower rate of adverse events, and higher feasibility (but its likely lower effectiveness with the standard dosage regimen), future analyses should assess the cost-effectiveness of the two treatments for health policy considerations.…”

Assessment of novel pre-erythrocytic malaria vaccines in humans by Venkatraman, N

“…In addition to humoral immunity, it is widely recognised that T-cell mechanisms are likely to play an important role in malaria immunity and heterologous prime-boost regimes using viral-vectored vaccines have been shown to induce potent T-cell responses. …”

Multi-species rotational grazing of small ruminants regenerates undergrowth vegetation while controlling weeds in the oil palm silvopastoral system by Tohiran, Kamil Azmi, Nobilly, Frisco, Zulkifli, Raja, Yahya, Muhammad Syafiq, Norhisham, Ahmad Razi, Rasyidi, Md Zainal, Azhar, Badrul

“…The use of single-species livestock grazing is likely to cause oil palm growers to use herbicides to control undesirable weeds. …”
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The level of knowledge, attitude and practice towards Covid-19 immunisation among medical students in public medical schools in Malaysia by Mohamad Zainal, Nurul Hayati, Mohammed Ayyub, Safiyya, Yi, Chang Fang, Zaman, Arif Najmi Shahrir, Mohd Nor, Nurul Huda, Omar, Norsuhana, Ku Mohd Noor, Ku Mastura, Hamimi Wahid, Hanan

“…Respondents in the age group of 21 to 24 years old (p < 0.001) and 25 to 29 years old (p = 0.016), and Indian ethnicity (p = 0.006) were more likely to have good knowledge. Respondents registered in Malaysia’s National COVID-19 vaccination program were considered as having a positive attitude (n = 264, 61.8). …”
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Model of motivational forces influencing academic achievement among secondary school students through the mediation of flow by Syed Mustafa, Sharifah Muzila

“…It can be concluded that students with higher intrinsic and learning efficacy motivation were more likely to experience higher flow and thus perform better in their examination. …”
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Rotor angle stability-constrained dispatch and control of large-scale wind penetrated power system by Yuan, Heling

“…In general, four main effects on power system transient stability are: 1) wind generation has no contribution to system inertia and system with synchronous generators replaced by wind turbines will lead to reduction of inertia, 2) power electronics converter-based interfacing is added when wind turbines are implemented, which will change the dynamic behavior of the system, 3) power dispatch of synchronous machines will change fast to compensate wind power variation, 4) the magnitude and direction of power flows will fluctuate quickly and randomly in the transmission lines. Hence, it is an essential and significant problem to maintain system’s stability with high level wind power penetration. …”
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Extreme learning machines for feature learning by Liyanaarachchi Lekamalage, Chamara Kasun

“…Hierarchal features consist of multiple levels and the low level features represent edges of an image such as lines and curves while high level features represent parts of the image such as nose, eyes of a face. …”
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Dynamics and stability of evaporating and condensing liquid layers by Wei, Tao

“…Finally, conclusions are drawn, and perspectives of future study based on these works have been proposed, including to model the dynamics of thin evaporating droplets with moving contact lines resulting from the successive touchdown of an evaporating layer and to investigate the relation between short-wave convection and long-wave deformation instabilities in the presence of phase change.…”
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Evolutionary explanations and the debunking of moral beliefs by Cofnas, N

“…I argue that our innate moral faculty is likely not the product of natural selection, but rather social selection. …”

Magnetoresistive sensor development roadmap (non-recording applications) by Zheng, Chao, Zhu, Ke, De Freitas, Susana Cardoso, Chang, Jen-Yuan, Davies, Joseph E., Eames, Peter, Freitas, Paulo P., Kazakova, Olga, Kim, Cheol Gi, Leung, Chi-Wah, Liou, Sy-Hwang, Ognev, Alexey, Piramanayagam, S. N., Ripka, Pavel, Samardak, Alexander, Shin, Kwang-Ho, Tong, Shi-Yuan, Tung, Mean-Jue, Wang, Shan X., Xue, Songsheng, Yin, Xiaolu, Pong, Philip W. T.

“…This paper provides a framework for MR sensor technology (non-recording applications) to be used for public and private R&D planning, in order to provide guidance into likely MR sensor applications, products, and services expected in the next 15 years and beyond.…”
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Foot care behaviours and associated factors among patients with type 2 diabetes: a cross-sectional study by Ang, Chin-Siang, Goh, Kelley Fann Ing, Lodh, Nandika, Qin, Vicky Mengqi, Liew, Huiling, Sidhu, Harvinder Raj Singh, Ng, Jun Jie, Subramaniam, Tavintharan, Tan, Elaine, Koh, Gerald Choon Huat, Best, James, Wong, Julian, Car, Josip, Ho, Andy Hau Yan, Venkataraman, Kavita

“…The logistic regression analysis showed that current smokers were 60% less likely to practice good FC compared to non-smokers (odds ratio (OR) = 0.40; 95%; confidence interval (CI)= 0.22–0.73). …”
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Estimating building vulnerability to volcanic ash fall for insurance and other purposes by Jenkins, Susanna F., Magill, C. R., Wilson, T. M., McMullan, K., Kandlbauer, J., Blong, R. J., Grasso, P.

“…Ash fall vulnerability curves or functions, which relate the magnitude of ash fall to likely damage, are the most developed for buildings, although there have been important recent advances for agriculture and infrastructure. …”
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Characterization and gene expression analysis of the cir multi-gene family of plasmodium chabaudi chabaudi (AS) by Lawton, Jennifer, Brugat, Thibaut, Yan, Yam Xue, Reid, Adam James, Böhme, Ulrike, Otto, Thomas Dan, Pain, Arnab, Jackson, Andrew, Berriman, Matthew, Cunningham, Deirdre, Preiser, Peter Rainer, Langhorne, Jean

“…Conclusions: In conclusion, the large number of cir genes and their expression throughout the intraerythrocytic cycle of development indicates that CIR proteins are likely to be important for parasite survival. In particular, the detection of dominant cir transcripts at the peak of P. chabaudi infection supports the idea that CIR proteins are expressed, and could perform important functions in the biology of this parasite. …”
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