Multidose transient transfection of human embryonic kidney 293 cells modulates recombinant adeno‐associated virus2/5 Rep protein expression and influences the enrichment fraction of filled capsids by Srinivasan, Prasanna, Canova, Christopher T, Sha, Sha, Nguyen, Tam NT, Joseph, John, Sangerman, Jose, Maloney, Andrew J, Katsikis, Georgios, Ou, Rui Wen, Hong, Moo Sun, Ng, Jaclyn, Yuan, Arella, Antov, Daniel, Song, Sally, Chen, Wenyu, Neufeld, Caleb, Wolfrum, Jacqueline M, Barone, Paul W, Sinskey, Anthony J, Springs, Stacy L, Braatz, Richard D

“…Here, we extend the model by quantifying the expression dynamics of total Rep proteins and their influence on the key steps of rAAV2/5 production using a multiple dosing transfection of human embryonic kidney 293 (HEK293) cells. …”
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New Zealand-Singapore defense relations in a volatile world by Muhammad Faizal Bin Abdul Rahman

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Effect of temperature variations on the fabrication of SLS-Na2CO3-ES-P2O5-CaF2-Al2O3 based bioglass-ceramics by Ismail, Nur Quratul Aini, Sa’at, Nor Kamilah, Mohd Zaid, Mohd Hafiz, Zainuddin, Norhazlin, Mayzan, Mohd Zul Hilmi

“…The results showed that at a sintering temperature of 950 °C, the crystallization of fluorapatite was the main phase. Moreover, the high density and optimum linear shrinkage were obtained as the sintering temperature increased. …”

Search for a third-generation leptoquark coupled to a τ lepton and a b quark through single, pair, and nonresonant production in proton-proton collisions at √𝑠 = 13 TeV by Hayrapetyan, A., Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Escalante Del Valle, A., Hussain, P. S., Jeitler, M., Krammer, N., Liko, D., Mikulec, I., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M.

“…Upper limits at the 95% confidence level are placed on the LQ production cross section in the LQ mass range 0.5–2.3 TeV, and up to 3 TeV for t-channel LQ exchange. …”
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Measurement of boosted Higgs bosons produced via vector boson fusion or gluon fusion in the H → bb¯ decay mode using LHC proton-proton collision data at √s = 13 TeV by Hayrapetyan, A., Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Hussain, P. S., Jeitler, M., Krammer, N., Li, A., Liko, D., Mikulec, I., Schieck, J., Schöfbeck, R., Schwarz, D., Sonawane, M., The CMS collaboration

“…The result is based on a data set with a center-of-mass energy of 13 TeV collected in 2016–2018 with the CMS detector at the LHC and corresponds to an integrated luminosity of 138 fb−1. …”
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Detection of low frequency artemisinin resistance mutations, C469Y, P553L and A675V, and fixed antifolate resistance mutations in asymptomatic primary school children in Kenya by Osoti, V, Wamae, K, Ndwiga, L, Gichuki, PM, Okoyo, C, Kepha, S, Keitany, K, Kandie, R, Aricha, S, Kiplagat, R, Mwandawiro, C, Bejon, P, Snow, RW, Ochola-Oyier, LI

“…Results: Pfk13 mutations associated with artemisinin resistance were present as mixed genotype infections for the C469Y mutation in 23 samples (4%), the A675V mutation in 2 samples (1.7%), and the P553L mutation in 7 samples (1.2%). …”

The performances of cationic starch (CS) and sodium carboxymethyl celluloses (CMC-Na) as a dry strength additives (DSA) on A4 wastepaper by Main, Nor Mazlana, Hishamuddin, Nurfarhani, Marsi, Noraini, Eza, Mohd Faizal, Masrol, Shaiful Rizal

“…The CS and CMC-Na were incorporated with to pulp slurry in different dosages (0.5% - 2.0%) during stock preparation. The basic weight of 80 g/m2 was made for each treatment. …”
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Assessing the impact of anthropogenic pollution on isoprene-derived secondary organic aerosol formation in PM2.5 collected from the Birmingham, Alabama, ground site during the 2013 Southern Oxidant and Aerosol Study by Guo, Hongyu, Rattanavaraha, Weruka, Stone, Elizabeth A., Offenberg, John H., Zhang, Zhenfa, Gold, Avram, Surratt, Jason D., Chu, Kevin, Riva, Matthieu, Lin, Ying-Hsuan, Baumann, Karsten, Shaw, Stephanie L., Budisulistiorini, Sri Hapsari, Edgerton, Eric S., King, Laura, Weber, Rodney J., Neff, Miranda E.

“…In the southeastern US, substantial emissions of isoprene from deciduous trees undergo atmospheric oxidation to form secondary organic aerosol (SOA) that contributes to fine particulate matter (PM2.5). Laboratory studies have revealed that anthropogenic pollutants, such as sulfur dioxide (SO2), oxides of nitrogen (NOx), and aerosol acidity, can enhance SOA formation from the hydroxyl radical (OH)-initiated oxidation of isoprene; however, the mechanisms by which specific pollutants enhance isoprene SOA in ambient PM2.5 remain unclear. …”
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Tribological properties of three-dimensionally printed Ti-6Al-4V material via electron beam melting process tested against 100Cr6 steel without and with Hank's solution by Khun, Nay Win, Toh, Wei Quan, Tan, Xi Peng, Liu, Erjia, Tor, Shu Beng

“…Three-dimensionally (3D) printed Ti–6Al–4V (Ti64) samples via an electron beam melting (EBM) process were developed to investigate their microstructure and mechanical and tribological properties in comparison with those of commercial Ti64 samples. …”
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Asymmetric synthesis of N-benzyl-5-methylhydroxy-piperidone and modular synthesis of C1-substituent tetrahydroisoquinolines (THIQ) and C2-symmetric bisisoquinolines (C2-BIQ) and their catalytic application in enantioselective Henry reaction by Khong, Duc Thinh

“…The two asymmetric synthetic approaches provided a significant improvement in the overall yield of N-benzyl-5-methoxy-piperidone product. While the chiral auxiliary approach offererd enantiopure product in up to 20% yield afet six step, synthetic method using lipase provided up to 45% overall yield afeter six steps, which are higher comparing to Gallagher’s enzymatic resolution approach (approximately 15% yield after five steps). …”
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Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, SE, Kalinga, WF, Salkeld, J, Mtaka, IM, Ahmed, S, Milando, F, Diouf, A, Bundi, CK, Balige, N, Hassan, O, Mkindi, CG, Rwezaula, S, Athumani, T, Mswata, S, Lilolime, NS, Simon, B, Msami, H, Mohamed, M, David, DM, Mohammed, L, Nyaulingo, G, Mwalimu, B, Juma, O, Mwamlima, TG, Sasamalo, IA, Mkumbange, RP, Kamage, JJ, Barrett, JR, King, LDW, Hou, MM, Pulido, D, Carnrot, C, Lawrie, AM, Cowan, RE, Nugent, FL, Roberts, R, Cho, J-S, Long, CA, Nielsen, CM, Miura, K, Draper, SJ, Olotu, AI, Minassian, AM

“…</p> <br> <p><strong>Methods:</strong> We did a non-randomised, phase 1b, single-centre, dose-escalation, age de-escalation, first-in-human trial of RH5.1/Matrix-M in Bagamoyo, Tanzania. We recruited healthy adults (aged 18–45 years) and children (aged 5–17 months) to receive the RH5.1/Matrix-M vaccine candidate in the following three-dose regimens: 10 μg RH5.1 at 0, 1, and 2 months (Adults 10M), and the higher dose of 50 μg RH5.1 at 0 and 1 month and 10 μg RH5.1 at 6 months (delayed-fractional third dose regimen; Adults DFx). …”

Biological characterization of RNA polymerase proteins from human 2009 pandemic H1N1 and low pathogenic avian H5N2 and H9N2 influenza viruses by Myaing, Myint Zu

“…Therefore, we have challenged mice with purified soluble PA protein (pH1N1/471 and H5N2/F118 strains), insoluble PB2 and PB1 proteins (pH1N1/471 strain). …”
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Two-dimensional (2D) covalent organic framework as efficient cathode for binder-free lithium-ion battery by Yao, Chang-Jiang, Wu, Zhenzhen, Xie, Jian, Yu, Fei, Guo, Wei, Xu, Zhichuan Jason, Li, Dong-Sheng, Zhang, Shanqing, Zhang, Qichun

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Ultra-high bit rate optical soliton communication by Shum, Ping, Gong, Yandong, Dong, Hui, Tang, Ming, Yu, Xia, Lai, Wenn Jing, Ning, Guoxiang

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Influence of welding on the strength of high performance steels by Zhang, Xing-Zhao, Zhao, Ming-Shan, Chiew, Sing-Ping, Lee, Chi-King, Fung, Tat-Ching

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Mesoporous Co3O4 and CoO@C topotactically transformed from chrysanthemum-like Co(CO3)0.5(OH)·0.11H2O and their lithium-storage properties by Xiong, Shenglin, Chen, Jun Song, Lou, David Xiong Wen, Zeng, Hua Chun

“…In this work, a novel hydrothermal route is developed to synthesize cobalt carbonate hydroxide, Co(CO3)0.5(OH)·0.11H2O. In this method, sodium chloride salt is utilized to organize single-crystalline nanowires into a chrysanthemum-like hierarchical assembly. …”
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Formulation, physicochemical, and sensory evaluation of cookies prepared from Sacha Inchi Oil Meal (SIOM) by Christopher, Jeffi, Tan, Chin Ping, Wasoh, Helmi, Tang, Teck-Kim, Lee, Yee-Ying, Lai, Oi Ming

“…This study developed the cookies by blending SIOM with wheat flour at 5, 10, 20, and 30% (w/w), respectively. Physical properties, proximate composition, and sensory study were evaluated on the cookies. …”
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An analysis of roadside particulate matter pollution and population exposure over the Pearl River Delta region of China under clear-sky condition using new ultra-high-resolution PM2.5 satellite-retrieval algorithms by Wu, Yi, Lee, Harry Fung, Deng, Ruru, Yim, Steve Hung Lam

“…Our results show that the retrieved PM2.5 had a promising consistency with PM2.5 measurements at general and roadside stations (R 2 = 0.86; RMSE = 7.72 µg m−3). …”
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Two types of new three-dimensional d–f heterometallic coordination polymers based on 2-(pyridin-3-yl)-1H Imidazole-4,5-dicarboxylate and oxalate ligands : syntheses, structures, luminescence, and magnetic properties by Cai, Song-Liang, Zheng, Sheng-Run, Wen, Zhen-Zhen, Fan, Jun, Wang, Ning, Zhang, Wei-Guang

“…Two types of new d–f heterometallic coordination frameworks, [Ln2M(μ3-HPyIDC)2(ox)2(H2O)4]·4H2O [Ln = Sm, M = Co (1); Ln = Sm, M = Fe (2); Ln = Eu, M = Co (3); Ln = Eu, M = Fe (4); Ln = Gd, M = Co (5); H3PyIDC = 2-(pyridine-3-yl)-1H-4,5-imidazoledicarboxylic acid; ox = oxalate] for type I and [Ln2Ag3(μ5-PyIDC)(μ6-PyIDC)(μ2-OH)(ox)(H2O)2] [Ln = Sm (6); Gd (7); Tb (8); Dy (9)] for type II, were prepared under hydrothermal conditions and structurally characterized. …”
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Phase transformation and mechanical properties of new bioactive glass-ceramics derived from CaO–P2O5–Na2O–B2O3–SiO2 glass system by Loh, Zhi Wei, Mohd Zaid, Mohd Hafiz, Matori, Khamirul Amin, Kechik, Mohd Mustafa Awang, Fen, Yap Wing, Mayzan, Mohd Zul Hilmi, Liza, Shahira, Cheong, Wei Mun

“…This work investigates the role of sintering temperature on bioactive glass-ceramics derived from the new composition CaO–P2O5–Na2O–B2O3–SiO2 glass system. The sintering behaviour of the samples’ physical, structural, and mechanical properties is highlighted in this study. …”
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