Collective synthesis of 4-Hydroxy-2-pyridone alkaloids and their antiproliferation activities by Ding, Feiqing, Leow, Min Li, Ma, Jimei, William, Ronny, Liao, Hongze, Liu, Xue-Wei

“…Interestingly, among the six tumor cell lines investigated, torrubiellone C was found to induce potent and apoptotic inhibitory activities on Jurkat T cells with IC50 values of 7.05 μm. …”
Get full text
Get full text
Get full text

Substation reliability and its impacts on composite system adequacy by Ren, Shuhua

“…Failure events in substations and switching stations often result in multiple outages of generators, lines, and/or loads in power system. Station-originated outages are normally of short duration but their effect on the security and stability of power systems may be quite severe. …”
Get full text

A model green city? : the history of conservation discourse in Singapore 1965 to the present by Tan, Yee Ting

“…Promoting herself as the “City in a Garden”, it’s difficult to ascertain the boundaries between humans and nature. Along these lines of thought, is the problem of conservation. …”
Get full text

Peroxisome proliferator-activated receptors and caloric restriction-common pathways affecting metabolism, health, and longevity by Duszka, Kalina, Gregor, András, Guillou, Hervé, König, Jürgen, Wahli, Walter

“…Consequently, several lines of evidence suggest that PPARs might be indispensable for beneficial outcomes related to CR. …”
Get full text

Viral content: a theory of vaccine hesitancy based on information encountering in the greater Manila area, Philippines by Sacramento, Simon Philip R., Sipin, Ian Dominic P.

“…Background: Ground experiences of the researchers indicate substantial concern about the side-effects of the AstraZeneca vaccine in some individuals who lined up to get vaccinated. The Philippine Department of Health, Food and Drug Administration temporarily suspended the administration of the AstraZeneca vaccine to persons below 60 years old on April 8, 2021, due to reports of “rare cases of blood clots with low platelets detected in some individuals inoculated with the vaccine.” …”
Get full text

To study the commercial and operational advantages and disadvantages of mega-container ships (>14,000TEU) by Lai, Marie Jinbao

“…In order to bring down the per-unit cost of transporting the containers, many shipping lines have began to order container vessels with increased container carrying capacity. …”
Get full text

Gambling island : a look at Singapore Pools and its role on gambling in Singapore society by Ang, Darren

“…Through qualitative research, I then try to show that Singapore Pools has managed to “diffuse” itself into the daily lives of Singaporeans, blurring the lines between institutional gambling and social gambling and further sustaining both institutional gambling as well as social gambling.…”
Get full text

When east meets west: beauty standards and ideals in Singapore by Dhillon, Sasha Kaur

“…Through my interviews, I discovered that Singapore constructs along unique lines – intertwining both Eastern and Western cultures with heavy emphasis on themes like skin colour, gender and race. …”
Get full text

Mapping refuse profile in Singapore old dumping ground through electrical resistivity, S-wave velocity and geotechnical monitoring by Yin, Ke, Tong, Huan Huan, Noh, Omar, Wang, Jing-Yuan, Giannis, Apostolos

“…Data were analyzed using an orthogonal set of plots by spreading 24 lines in two perpendicular geophone-orientation directions. …”
Get full text
Get full text

Biomateriality and organizing: towards an organizational perspective on food by Moser, C, Reinecke, J, Hond, FD, Svejenova, S, Croidieu, G

“…We use this analytical toolkit to introduce the different articles in the special issue and put forward some lines of future research.…”

A bi-functional three-terminal memristor applicable as an artificial synapse and neuron by Liu, Lingli, Dananjaya, Putu Andhita, Ang, Calvin Ching Ian, Koh, Eng Kang, Lim, Gerard Joseph, Poh, Han Yin, Chee, Mun Yin, Lee, Calvin Xiu Xian, Lew, Wen Siang

Get full text

Gut microbiota in colorectal cancer: biological role and therapeutic opportunities by Pandey, Himani, Tang, Daryl W. T., Wong, Sunny Hei, Lal, Devi

“…While CRC is thought to be an interplay between genetic and environmental factors, several lines of evidence suggest the involvement of gut microbiota in promoting inflammation and tumor progression. …”
Get full text

Laser assisted micro patterning atop shape memory polymer by Goh, Chee Siew.

“…The aim of this project is built on this property of the SMP, in which micro-sized arrays in the form of protrusion bumps and lines will be created onto the SMP surface. SMP has existed for a long time and in the past few years, its usefulness has been illustrated in many industries include the biomedical industry. …”
Get full text

Miniaturized planar filters for UWB application by Lau, Yizhang.

“…There are several novels on how to improve a MMR design like using aperture-Backed PCML and Capacitive-Ended Interdigital Coupled lines. In this project, a microstrip stub-loaded dual-mode resonator doublets design is proposed. …”
Get full text

Investigating the role of RUNX3 in Epithelial-Mesenchymal Transition (EMT). by Muhammad Bakhait Rahmat.

“…Further biochemical studies need to be followed up to investigate the mechanistic principles involved in RUNX3 mediated inhibition of EMT in intermediate stage A549 cell lines.…”
Get full text

Real time power system simulation using Opal-RT by Shi, Donghan

“…The power system model consists of generators, power distribution lines, transformers, power electronics converters and loads on both AC and DC buses. …”
Get full text

Interleukin-26 (IL-26) is a novel anti-microbial peptide produced by T cells in response to staphylococcal enterotoxin by Woetmann, Anders, Alhede, Morten, Dabelsteen, Sally, Bjarnsholt, Thomas, Rybtke, Morten, Nastasi, Claudia, Krejsgaard, Thorbjørn, Andersen, Mads Hald, Bonefeld, Charlotte M., Geisler, Carsten, Givskov, Michael, Odum, Niels

“…Here we show that (i) skin T cells in chronic wounds infected with S. aureus express interleukin-26 (IL-26) in situ, (ii) staphylococcal enterotoxins (SE) trigger IL-26 expression in T cell lines and primary skin T cells, and (iii) IL-26 triggers death and inhibits biofilm formation and growth of S. aureus. …”
Get full text
Get full text

Systems medicine disease : disease classification and scalability beyond networks and boundary conditions by Berlin, Richard, Gruen, Russell, Best, James

“…When Disease is viewed beyond the thresholds of lines and threshold boundaries, disease definition is not only the result of reductionist, mechanistic categories which reluctantly face re-composition. …”
Get full text
Get full text

Entangled exclusions: borders, frontiers and urban geopolitics from northeast India by Das, P, Mittal, G, Sarma, J

“…These have, in turn, led to further displacement, enclavization, and ghettoization of minority communities who are deemed ‘non-native’ along ethnocentric lines. Taking two cases from Shillong and Guwahati, we introduce the concept of entangled exclusions to analyse the layered, intertwined, multi-scalar nature of divides within these frontier cities. …”

3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay by Zhang, Yingqi, Jiang, Fengtao, Zhao, Charles Yunduo, Cho, Ann-Na, Fang, Guocheng, Cox, Charles D., Zreiqat, Hala, Lu, Zu Fu, Lu, Hongxu, Ju, Arnold Lining

Get full text