Genetic and observational associations of nuclear magnetic resonance-measured lipid-related traits and atherosclerotic cardiovascular mortality in the Mexico City Prospective Study by Wang, Y

“…In cross-sectional analyses, complex correlation patterns within and across the same lipoprotein category within NMR lipid panels were observed, in line with their biochemical structures and interactions in lipid metabolism. …”

论阮籍诗文中的逃避主义 = Escapism in the literary works of Ruan Ji by 王岳明 Wang, Yueming

“…The concept of “artistic conception” (Yi Jing) will first be introduced, followed by and examination of the escape related “artistic conception” of “Dong Ping Fu-Prose”, and selected four-worded “Yong Huai Poems” and five-worded “Yong Huai Poems” respectively. …”
Get full text

Towards A Robust Integrated Urban Mobility System: Public Transit and Ride-Sharing Systems by Guo, Xiaotong

“…A nominal (non-robust) optimization model for the transit frequency setting problem (TFSP) under a single transit line setting is first proposed. The model is then extended to the RO-based formulation to incorporate demand uncertainty. …”
Get full text
Get full text

Phase-controllable growth of ultrathin 2D magnetic FeTe crystals by Kang, Lixing, Ye, Chen, Zhao, Xiaoxu, Zhou, Xieyu, Hu, Junxiong, Li, Qiao, Liu, Dan, Das, Chandreyee Manas, Yang, Jiefu, Hu, Dianyi, Chen, Jieqiong, Cao, Xun, Zhang, Yong, Xu, Manzhang, Di, Jun, Tian, Dan, Song, Pin, Kutty, Govindan, Zeng, Qingsheng, Fu, Qundong, Deng, Ya, Zhou, Jiadong, Ariando, Ariando, Miao, Feng, Hong, Guo, Huang, Yizhong, Pennycook, Stephen J., Yong, Ken-Tye, Ji, Wei, Wang, Renshaw Xiao, Liu, Zheng

Get full text

Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes by McAllan, Liam, Baranasic, Damir, Villicaña, Sergio, Brown, Scarlett, Zhang, Weihua, Lehne, Benjamin, Adamo, Marco, Jenkinson, Andrew, Elkalaawy, Mohamed, Mohammadi, Borzoueh, Hashemi, Majid, Fernandes, Nadia, Lambie, Nathalie, Williams, Richard, Christiansen, Colette, Yang, Youwen, Zudina, Liudmila, Lagou, Vasiliki, Tan, Sili, Castillo-Fernandez, Juan, King, James W. D., Soong, Richie, Elliott, Paul, Scott, James, Prokopenko, Inga, Cebola, Inês, Loh, Marie, Lenhard, Boris, Batterham, Rachel L., Bell, Jordana T., Chambers, John Campbell, Kooner, Jaspal S., Scott, William R.

Get full text

An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study by Slieker, Roderick C., Münch, Magnus, Donnelly, Louise A., Bouland, Gerard A., Dragan, Iulian, Kuznetsov, Dmitry, Elders, Petra J. M., Rutter, Guy A., Ibberson, Mark, Pearson, Ewan R., Hart, Leen M. 't, van de Wiel, Mark A., Beulens, Joline W. J.

Get full text

Using brain structural neuroimaging measures to predict psychosis onset for individuals at clinical high-risk by Zhu, Yinghan, Maikusa, Norihide, Radua, Joaquim, Sämann, Philipp G., Fusar-Poli, Paolo, Agartz, Ingrid, Andreassen, Ole A., Bachman, Peter, Baeza, Inmaculada, Chen, Xiaogang, Choi, Sunah, Corcoran, Cheryl M., Ebdrup, Bjørn H., Fortea, Adriana, Garani, Ranjini Rg, Glenthøj, Birte Yding, Glenthøj, Louise Birkedal, Haas, Shalaila S., Hamilton, Holly K., Hayes, Rebecca A., He, Ying, Heekeren, Karsten, Kasai, Kiyoto, Katagiri, Naoyuki, Kim, Minah, Kristensen, Tina D., Kwon, Jun Soo, Lawrie, Stephen M., Lebedeva, Irina, Lee, Jimmy, Loewy, Rachel L., Mathalon, Daniel H., McGuire, Philip, Mizrahi, Romina, Mizuno, Masafumi, Møller, Paul, Nemoto, Takahiro, Nordholm, Dorte, Omelchenko, Maria A., Raghava, Jayachandra M., Røssberg, Jan I., Rössler, Wulf, Salisbury, Dean F., Sasabayashi, Daiki, Smigielski, Lukasz, Sugranyes, Gisela, Takahashi, Tsutomu, Tamnes, Christian K., Tang, Jinsong, Theodoridou, Anastasia, Tomyshev, Alexander S., Uhlhaas, Peter J., Værnes, Tor G., van Amelsvoort, Therese A. M. J., Waltz, James A., Westlye, Lars T., Zhou, Juan H., Thompson, Paul M., Hernaus, Dennis, Jalbrzikowski, Maria, Koike, Shinsuke

Get full text

Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, SE, Kalinga, WF, Salkeld, J, Mtaka, IM, Ahmed, S, Milando, F, Diouf, A, Bundi, CK, Balige, N, Hassan, O, Mkindi, CG, Rwezaula, S, Athumani, T, Mswata, S, Lilolime, NS, Simon, B, Msami, H, Mohamed, M, David, DM, Mohammed, L, Nyaulingo, G, Mwalimu, B, Juma, O, Mwamlima, TG, Sasamalo, IA, Mkumbange, RP, Kamage, JJ, Barrett, JR, King, LDW, Hou, MM, Pulido, D, Carnrot, C, Lawrie, AM, Cowan, RE, Nugent, FL, Roberts, R, Cho, J-S, Long, CA, Nielsen, CM, Miura, K, Draper, SJ, Olotu, AI, Minassian, AM

“…<p><strong>Background:</strong> A blood-stage Plasmodium falciparum malaria vaccine would provide a second line of defence to complement partially effective or waning immunity conferred by the approved pre-erythrocytic vaccines. …”

High p16 expression and heterozygous RB1 loss are biomarkers for CDK4/6 inhibitor resistance in ER+ breast cancer by Palafox, Marta, Monserrat, Laia, Bellet, Meritxell, Villacampa, Guillermo, Gonzalez-Perez, Abel, Oliveira, Mafalda, Brasó-Maristany, Fara, Ibrahimi, Nusaibah, Kannan, Srinivasaraghavan, Mina, Leonardo, Herrera-Abreu, Maria Teresa, Òdena, Andreu, Sánchez-Guixé, Mònica, Capelán, Marta, Azaro, Analía, Bruna, Alejandra, Rodríguez, Olga, Guzmán, Marta, Grueso, Judit, Viaplana, Cristina, Hernández, Javier, Su, Faye, Lin, Kui, Clarke, Robert B., Caldas, Carlos, Arribas, Joaquín, Michiels, Stefan, García-Sanz, Alicia, Turner, Nicholas C., Prat, Aleix, Nuciforo, Paolo, Dienstmann, Rodrigo, Verma, Chandra Shekhar, Lopez-Bigas, Nuria, Scaltriti, Maurizio, Arnedos, Monica, Saura, Cristina, Serra, Violeta

“…Here, we show that p16 overexpression is associated with reduced antitumor activity of CDK4/6 inhibitors in patient-derived xenografts (n = 37) and estrogen receptor-positive breast cancer cell lines, as well as reduced response of early and advanced breast cancer patients to CDK4/6 inhibitors (n = 89). …”
Get full text

Novel method of probe design for characterising unclassified microbial taxa in wastewater by Tan, Shi Ming

“…Shimingles; distinct clades were in line with two draft genomes recovered through genomic binning. …”
Get full text

InAlN/GaN high electron mobility transistors on Si for RF applications by Xing, Weichuan

“…Also, device geometries including gate length, line-to-space ratio of the nanostripchannel and gate-to-source distance have been studied. …”
Get full text
Get full text

Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures by Belov, Vladimir, Erwin-Grabner, Tracy, Aghajani, Moji, Aleman, Andre, Amod, Alyssa R., Basgoze, Zeynep, Benedetti, Francesco, Besteher, Bianca, Bülow, Robin, Ching, Christopher R. K., Connolly, Colm G., Cullen, Kathryn, Davey, Christopher G., Dima, Danai, Dols, Annemiek, Evans, Jennifer W., Fu, Cynthia H. Y., Gonul, Ali Saffet, Gotlib, Ian H., Grabe, Hans J., Groenewold, Nynke, Hamilton, J. Paul, Harrison, Ben J., Ho, Tiffany C., Mwangi, Benson, Jaworska, Natalia, Jahanshad, Neda, Klimes-Dougan, Bonnie, Koopowitz, Sheri-Michelle, Lancaster, Thomas, Li, Meng, Linden, David E. J., MacMaster, Frank P., Mehler, David M. A., Melloni, Elisa, Mueller, Bryon A., Ojha, Amar, Oudega, Mardien L., Penninx, Brenda W. J. H., Poletti, Sara, Pomarol-Clotet, Edith, Portella, Maria J., Pozzi, Elena, Reneman, Liesbeth, Sacchet, Matthew D., Sämann, Philipp G., Schrantee, Anouk, Sim, Kang, Soares, Jair C., Stein, Dan J., Thomopoulos, Sophia I., Uyar-Demir, Aslihan, van der Wee, Nic J. A., van der Werff, Steven J. A., Völzke, Henry, Whittle, Sarah, Wittfeld, Katharina, Wright, Margaret J., Wu, Mon-Ju, Yang, Tony T., Zarate, Carlos, Veltman, Dick J., Schmaal, Lianne, Thompson, Paul M., Goya-Maldonado, Roberto

Get full text

Microfluidic platform for negative enrichment of circulating tumor cells by Sajay, Bhuvanendran Nair Gourikutty, Chang, Chia-Pin, Ahmad, Hamizah, Khuntontong, Puttachat, Wong, Chee Chung, Wang, Zhiping, Puiu, Poenar Daniel, Soo, Ross, Rahman, Abdur Rub Abdur

“…This negative enrichment method employs upstream immunomagnetic depletion to deplete CD45-positive WBCs followed by a microfabricated filter membrane to perform chemical-free RBC depletion and target cells isolation. Experiments of spiking two cell lines, MCF-7 and NCI-H1975, in the whole blood show an average of >90 % cell recovery over a range of spiked cell numbers. …”
Get full text
Get full text

Towards an optimal and unbiased approach for tumor cell isolation by Sajay, Bhuvanendran Nair Gourikutty, Chang, Chia-Pin, Ahmad, Hamizah, Chung, Wong Chee, Puiu, Poenar Daniel, Rahman, Abdur Rub Abdur

“…This approach achieves an average of >90 % recovery of spiked tumor cells and >99 % total WBC depletion in whole blood across multiple cell lines, in a simple and easy-to-use assay. …”
Get full text
Get full text

Social tags as news event detectors by Chua, Alton Yeow Kuan, Razikin, Khasfariyati, Goh, Dion Hoe-Lian

“…First, the performance of using spikes and bursts to detect news events was found to be comparable. …”
Get full text
Get full text

Investigating the potential of axonopus compressus to phytoremediate molybdenum by Eng, Zhi Xian

“…Mo accumulation in dry tissue of AC peaked in Week 1 and gradually decreased with time. Control AC and pots spiked with more than 20 ppm exhibited stunted growth two weeks after treatment. …”
Get full text

An on-nanoparticle rolling-circle amplification platform for ultrasensitive protein detection in biological fluids by Yan, Juan, Song, Shiping, Li, Bing, Zhang, Qingzhi, Huang, Qing, Zhang, Hua, Fan, Chunhai

“…The nanoRCA assay is applicable to the detection of two tumor markers in biological fluids: prostate-specific antigen in spiked sera and interleukin-8 in saliva.…”
Get full text
Get full text

Exposure to Pb-halide perovskite nanoparticles can deliver bioavailable Pb but does not alter endogenous gut microbiota in zebrafish by Patsiou, Danae, del Rio-Cubilledo, Cristina, Catarino, Ana Isabel, Summers, Stephen, Afiq Mohd Fahmi, Boyle, David, Fernandes, Teresa F., Henry, Theodore B.

“…Induction of mt2 and reduction of ala-d expression levels in liver tissues showed Pb bioavailability after 2-d and 4-d dietary exposure to perovskite-spiked feeds. Changes in gut microbiota of adult zebrafish were detected after 14-d exposure to Pb-spiked food, but no changes were detected from perovskite-NP spiked food. …”
Get full text

Calcined bone provides a reliable substrate for strontium isotope ratios as shown by an enrichment experiment by Snoeck, C, Lee-Thorp, J, Schulting, R, de Jong, J, Debouge, W, Mattielli, N

“…<p><b>Results</b></p> The strontium isotopic ratios of all samples immersed in the spiked solution were strongly modified showing that significant amounts of strontium had been adsorbed or incorporated. …”

Application of Fourier transform infrared spectroscopy to determine free fatty acid contents in palm olein by Che Man, Y.B., Setiowaty, G.

“…This set was prepared by spiking increasing amounts of oleic acid into a series of palm oleins that covers a wide range of FFA (0.08-1.04%). …”
Get full text