The natively disordered loop of Bcl-2 undergoes phosphorylation-dependent conformational change and interacts with Pin1 by Bharatham, Nagakumar, Chia, Joel, Mu, Yuguang, Baek, Kwanghee, Yoon, Ho Sup, Kang, CongBao

“…Finally, we show that the phosphorylated peptides of the Bcl-2 loop can bind Pin1, further substantiating the phosphorylation-mediated conformation change of Bcl-2.…”
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Holocene rate of slip and tentative recurrence interval for large earthquakes on the San Andreas fault, Cajon Pass, southern California by Sieh, Kerry, Weldon, Ray J.

“…The sum of the Holocene slip rate on the San Andreas (∼24.5 mm/yr) and the Quaternary rate on the San Jacinto (∼10 mm/yr) faults southeast of their junction is the same as the Holocene slip rate on the San Andreas farther northwest (∼34 mm/yr). …”
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Parameter optimization of evolving spiking neural networks using improved firefly algorithm for classification tasks / by Farezdzuan Roslan, 1992-, author 616568, Haza Nuzly Abdull Hamed, supervisor 308916, Fakulti Kejuruteraan. Sekolah Komputeran 619086

Parameter optimization of evolving spiking neural networks using improved firefly algorithm for classification tasks / by Farezdzuan Roslan, 1992-, author 616568

Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein by Zhang, Si Min, Liao, Ying, Neo, Tuan Ling, Lu, Yanning, Liu, Ding Xiang, Vahlne, Anders, Tam, James Pingkwan

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EEG data handling using AWS cloud computing for automatic spike detection in epilepsy patients by Rajput Kalpana Bharatsingh

“…In this work, we explore the feasibility of AWS-cloud based approach for handling large EEG data for automatic spike detection in epilepsy patients. The aim is to design a system which will allow neurologists to upload and download EEG data from any region for analysis purpose; in the future the data will be analysed by machine learning algorithms. …”
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Mechanism of charge transfer and its impacts on Fermi-level pinning for gas molecules adsorbed on monolayer WS2 by Zhou, Changjie, Yang, Weihuang, Zhu, Huili

“…The phenomenon of Fermi-level pinning was discussed in light of the traditional and orbital mixing charge transfer theories. …”
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Part I: Synthesis of sex pheromone of the pine sawfly, Macrodiprion Nemoralis. Part II: Synthetic studies towards the total synthesis of iriomoteolide-1a by Chin, Yen Jin

“…In the first part of this thesis, an elegant display of the CuI-Tol-BINAP-catalyzed asymmetric conjugate addition is established in the total synthesis of sex pheromone of the pine sawfly, Macrodiprion Nemoralis (SRRS-1). The key features of our strategy are: (I) one-pot DIBAL-H reduction–Wittig olefination, (II) olefin cross metathesis of fragment A and fragment B, and (III) a CuI-Tol-BINAP-catalyzed asymmetric conjugate addition using Grignard reagents in good yields and excellent stereoselectivities. …”
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Experimental and numerical studies of pin-ended S960 ultra-high strength steel press-braked channel section columns by Ong, Shao Quan

“…The structural testing programme were performed on two nonslender plain channel sections and comprised detailed measurements of initial global and local geometric imperfections, as well as a total of 10 flexural buckling tests on pin-ended columns buckling about their minor axes. …”
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Comparison and validation of sensors for 3D and 2D motion capture to measure 10-pin bowling specific kinematics by Lim, Matthew Jing Long

“…Ten pin bowling is a competitive sport that requires athletes to score as many pins possible using a bowling ball. …”
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Developing a system that uses ultrawide-band inertial measurement units to quantify selected 10-Pin skills in real-time by Wee, Joel Jiewei

“…Ten-pin bowling is a unique abstract sport that requires bowlers to deliver a 11-to-16-pound ball in a five-step approach for the ball to travel down the oiled lane to knock down 10 pins. …”
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Long-term slip rate of the southern San Andreas Fault from 10Be-26Al surface exposure dating of an offset alluvial fan by Ryerson, Frederick J., Van der Woerd, Jérôme, Klinger, Yann, Sieh, Kerry, Tapponnier, Paul, Mériaux, Anne-Sophie

“…We determine the long-term slip rate of the southern San Andreas Fault in the southeastern Indio Hills using 10Be and 26Al isotopes to date an offset alluvial fan surface. …”
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Improved flux pinning properties of Mg exceed MgB2 ceramics with B4C and Dy2O3 additions by Pham, Ha H., Le, Tien, Pham, An T., Kang, Won Nam, Nam, Nguyen H., Anh, Do T.K., Anh, Nguyen Hoang, Peh, Hoo Keong, Chen, Soo Kien, Man, Nguyen K., Hong, Vuong Thi Anh, Lee, Hanoh, Park, Tuson, Cuong, Le Viet, Hai, Phan, Huy, Nguyen Quang, Tran, Duc H.

“…According to collective pinning theory, δl pinning was identified as the dominant pinning type in the fabricated samples. …”
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Event-driven spiking neural networks using asynchronous-logic network-on-chip routers in field programmable gate array (FPGA) by Wu, Si

“…Compared with the second-generation neural network, SNN uses spikes to process information. The neuronal units in SNNs are only active when they receive or emit spikes, so it is event-driven, thus making it energy-efficient. …”
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High-density lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner by Correa, Yubexi, Del Giudice, Rita, Waldie, Sarah, Thépaut, Michel, Micciula, Samantha, Gerelli, Yuri, Moulin, Martine, Delaunay, Clara, Fieschi, Franck, Pichler, Harald, Haertlein, Michael, Forsyth, V. Trevor, Le Brun, Anton, Moir, Michael, Russell, Robert A., Darwish, Tamim, Brinck, Jonas, Wodaje, Tigist, Jansen, Martin, Martín, César, Roosen-Runge, Felix, Cárdenas, Marité

“…It is known that the SARS-CoV-2 spike (S) protein binds the HDL particle, probably depleting it of lipids and altering HDL function. …”
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Dok3 restrains neutrophil production of calprotectin during TLR4 sensing of SARS-CoV-2 spike protein by Loh, Jia Tong, Teo, Joey Kay Hui, Lam, Kong-Peng

“…In this study, we showed that Dok3 adaptor restrains calprotectin production by neutrophils in response to SARS-CoV-2 spike (S) protein engagement of TLR4. Dok3 recruits SHP-2 to mediate the de-phosphorylation of MyD88 at Y257, thereby attenuating downstream JAK2-STAT3 signaling and calprotectin production. …”
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Space charge induced beam loss on a high intensity proton synchrotron by Pine, B

Efficient multi-scale representation of visual objects using a biologically plausible spike-latency code and winner-take-all inhibition by Sanchez-Garcia, Melani, Chauhan, Tushar, Cottereau, Benoit R., Beyeler, Michael

“…We demonstrate that a network of 200 spiking neurons tuned to three SFs can efficiently represent objects with as little as 15 spikes per neuron. …”
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Zeolitic imidazolate frameworks activate endosomal Toll-like receptors and potentiate immunogenicity of SARS-CoV-2 spike protein trimer by Alsaiari, Shahad K., Nadeef, Seba, Daristotle, John L., Rothwell, William, Du, Bujie, Garcia, Johnny, Zhang, Linzixuan, Sarmadi, Morteza, Forster, Timothy A., Menon, Nandita, Lin, Stacey Qiaohui, Tostanoski, Lisa H., Hachmann, Nicole, Wang, Erika Yan, Ventura, John D., Barouch, Dan H., Langer, Robert, Jaklenec, Ana

“…The intrinsic adjuvant properties of ZIF-8, along with the efficient delivery and biomimetic presentation of a severe acute respiratory syndrome coronavirus 2 spike protein receptor-binding domain trimer, primed rapid humoral and cell-mediated immunity in a dose-sparing manner. …”
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Magmatic Na-rich phlogopite in a suite of gabbroic crustal xenoliths from Volcán San Pedro, Chilean Andes : evidence for a solvus relation between phlogopite and aspidolite by Costa, Fidel, Dungan, Michael, Singer, Brad S.

“…Magmatic Na-rich phlogopite (1–5 wt% Na2O) is present as a late-crystallizing mineral in two groups of texturally and mineralogically distinct gabbroic xenoliths at Volcán San Pedro (36°S, Chile), an Andean arc volcano. …”
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