Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Chapter 4 focuses on the site-specific glycosylation occupancy, and N- and O-glycan structures attached to virion derived SARS-CoV-2 spike glycoproteins. This glycan signature was compared to a stabilised prefusion trimeric spike, to a monomeric subunit of spike (S1) and to an antigen of a non-stabilised vaccine candidate, revealing subunit shedding of the S1 glycoprotein for the vaccine candidate. …”

Comparative effects of domain-specific human monoclonal antibodies against LGI1 on neuronal excitability by Sell, J, Rahmati, V, Kempfer, M, Irani, SR, Ritzau-Jost, A, Hallermann, S, Geis, C

“…However, only the LRR-specific mAbs increased the number of action potential firing together with enhanced initial instantaneous frequency and promoted spike-frequency adaptation, which were less pronounced after the EPTP mAb. …”

Microneedle‐mediated Delivery of Immunomodulators Restores Immune Privilege in Hair Follicles and Reverses Immune‐Mediated Alopecia by Younis, Nour, Puigmal, Núria, Kurdi, Abdallah El, Badaoui, Andrew, Zhang, Dongliang, Morales, Claudia, Saad, Anis, Cruz, Diane, Rahy, Nadim Al, Daccache, Andrea, Huerta, Triana, Deban, Christa, Halawi, Ahmad, Choi, John, Dosta, Pere, Lian, Christine, Artzi, Natalie, Azzi, Jamil R.

“…The accessibility of the skin provides an opportunity for local rather than systemic intervention to avoid broad immunosuppression. …”
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Mobile Robotic Platform for Contactless Vital Sign Monitoring by Huang, Hen-Wei, Chen, Jack, Chai, Peter R., Ehmke, Claas, Rupp, Philipp, Dadabhoy, Farah Z., Feng, Annie, Li, Canchen, Thomas, Akhil J., da Silva, Marco, Boyer, Edward W., Traverso, Giovanni

“…Without compensation, the skin temperature MAE is 1.3°C. Using the proposed compensation method, the skin temperature MAE is reduced to 0.3°C. …”
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A C-terminal peptide of TFPI-1 facilitates cytosolic delivery of nucleic acid cargo into mammalian cells by Fazil, Mobashar Hussain Urf Turabe, Chalasani, Madhavi Latha Somaraju, Choong, Yeu Khai, Schmidtchen, Artur, Verma, Navin Kumar, Saravanan, Rathi

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Design of a dual band planar inverted-F antenna for GMS/DCS mobile handset by Fang, Jun

“…This project involved the study of size miniaturization of microstrip antenna techniques: shorting pin and shorting wall, loading, shorted spiral printed antenna and stacked shorted patch antenna are fully discussed.…”
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Study on the wear characteristics of aluminium metal matrix composite with 15% Al2O3 and 20% Al2O3 by Chua, Swu Chun.

“…The objective of this dissertation was to study the wear characteristics and behaviour of aluminium metal matrix composite materials (MMCs), namely Duralcan 286 and Duralcan 284 as a pin material when mated against three types of dics materials.…”
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Crosslinked microneedle patch to extract interstitial fluid for diagnosis by Kang, Rong Jie

“…In this study, we have successfully developed a hydrogel microneedle based on hyaluronic acid derivative (methylcrylate modified hyaluronic acid, MeHA) and demonstrated its superior mechanical strength; having approximate 8 times the strength required for penetration into the skin. It was successfully penetrated into porcine cadaver skin, as well as the skin of a live mouse. …”
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Multiscale topological indices for the quantitative prediction of SARS CoV-2 binding affinity change upon mutations by Bi, Jialin, Wee, JunJie, Liu, Xiang, Qu, Cunquan, Wang, Guanghui, Xia, Kelin

“…Biologically, protein-protein interactions between SARS-CoV-2 surface spike (S) protein and human ACE2 protein are the key mechanism behind the COVID-19 disease. …”
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A two-stage automatic color thresholding technique by Pootheri, Shamna, Ellam, Daniel, Grübl, Thomas, Liu, Yang

“…The segmentation of skin cancer lesions will help doctors to automate skin cancer detection. …”
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Imprinting of IgA responses in previously infected individuals receiving bivalent mRNA vaccines (WT and BA.4/BA.5 or WT and BA.1) by Goh, Yun Shan, Fong, Siew-Wai, Hor, Pei Xiang, Loh, Chiew Yee, Tay, Matthew Zirui, Wang, Bei, Salleh, Siti Nazihah Mohd, Ngoh, Eve Zi Xian, Lee, Raphael Tze Chuen, Poh, Xuan Ying, Lee, I. Russel, Rao, Suma, Chia, Po Ying, Maurer-Stroh, Sebastian, Wang, Cheng-I, Leo, Yee Sin, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

“…Results: We found significantly lower fold change in serum binding IgA responses against BA.1, BA.5 and EG.5.1 spike in the bivalent booster group, compared with the monovalent (WT) booster group, following vaccination. …”
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Towards a computer that functions like the human brain by Lee, Seow Wei

“…Spike-Timing-Dependent Plasticity and unsupervised learning in the network is researched in this report. …”
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Free vibration properties of beetle elytron plate: Composite material, stacked structure and boundary conditions by Song, Yiheng, Hao, Ning, Ruan, Sihan, He, Chaochao, Quanjin, Ma

“…The results indicate that 1) the ranking of structural parameters on the 1st order frequency from a strong to weak sequence is as follows: length-to-width ratio, core height-to-thickness ratio, foam density and skin thickness; for the 2nd order natural frequency: length-to-width ratio, skin thickness, foam density and core height-to-thickness ratio. 2) Generally, an increase in the length-to-width ratio will reduce the frequency of the BEP, and increases in the core height-to-thickness ratio and skin thickness will raise its frequency. …”
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What does acne genetics teach us about disease pathogenesis? by Common, J. E. A., Barker, J. N., van Steensel, Maurice A. M.

“…Background: Acne vulgaris is a highly prevalent inflammatory skin disorder with a complex pathogenesis, characterized by comedones, papules, pustules and nodules. …”
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Infection patterns of scabies and tinea between inland and resettled indigenous Negrito communities in peninsular Malaysia by Er, Yi Xian, Than, Leslie Thian Lung, Muslim, Azdayanti, Yap, Nan Jiun, Tee, Mian Zi, Abdull-Majid, Nurmanisha, Lee, Soo Ching, Shahrizal, Shezryna, Lim, Yvonne Ai Lian

“…Skin infections cause significant health burden and affect underserved communities such as the indigenous Negrito communities disproportionately. …”
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Experimental and numerical investigations of hot-rolled stainless steel channel section columns susceptible to flexural buckling by Li, Shuai, Zhang, Lulu, Liang, Yating, Zhao, Ou

“…A thorough testing and numerical modelling programme has been conducted to investigate the minor-axis flexural buckling behaviour and resistances of pin-ended hot-rolled stainless steel channel section columns. …”
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Measuring membrane capacitance during a depolarizing stimulus by Chen, Peng., Gillis, Kevin., Xue, Renhao., Pui, Tze Sian.

“…It is critical to resolve the highly dynamic kinetic steps along the molecular cascade of exocytosis in order to pin down the specific actions of regulatory molecules and eventually decipher this complex and fundamental process.…”
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Identification of proteins and genes as potential biomarkers in brown-marbled grouper (Epinephelus fuscoguttatus forsskal) resistance to Vibrio sp by Low, Chen Fei

“…Skin lesion specimens observed under the scanning electron microscope revealed disintegration of skin around the lesion, and presence of bacterial cells under high magnification of 6000X. …”
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Understanding the implications of engineered nanoparticle induced autophagy in human epidermal keratinocytes in vitro by Gautam, Archana, Rakshit, Moumita, Nguyen, Kim Truc, Kathawala, Mustafa Hussain, Nguyen, Luong Thi Hien, Tay, Chor Yong, Wong, Esther, Ng, Kee Woei

“…While toxicological risks of applying these materials are generally regarded as low due to minute levels of penetration across the skin, our understanding of the physiological influence of potential cell-nanoparticle interactions in the skin is limited. …”
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Development of a vision-based gesture human-computer interface by Lim, Chun Ping.

“…From the evaluations, it was concluded that the two key modules, which are the skin segmentation by codebook method and the Kalman tracker, are robust. …”
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