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3861
DevOps for Databases : A practical guide to applying DevOps best practices to data-persistent technologies /
Published 2023“…Database administrators are no longer the only experts; site reliability engineers (SREs) and DevOps engineers are database experts as well. This blurring of the lines has led to increased responsibilities, making members of high-performing DevOps teams responsible for end-to-end ownership. …”
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software, multimedia -
3862
Empowering Teen Mental Fitness : A Guide for Managing Anxiety, Depression, Stress, and Suicide /
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software, multimedia -
3863
Empowering Teen Mental Fitness : A Guide for Managing ADHD/ADD, Bullying, PTSD, and Social Media /
Published 2024Get full text
software, multimedia -
3864
Sequence-Dependent & -Independent Effects of Intron-Mediated Enhancement (IME)
Published 2024“…In this study we report the design and execution of several massively parallel reporter assays (MPRAs), interrogating the effect of tens of thousands of synthetic and natural intron sequences on gene expression in the human HEK293T and HeLa cell lines. We observe that even with random internal sequence, most of these introns splice well and trigger IME. …”
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Thesis -
3865
Multi-criteria re-entrant jobs scheduling problems using GA and AHP
Published 2013“…The validation is conducted in two experiments, firstly single GA is implemented for the re-entrant lines and later a new combination of GA and AHP is carried out. …”
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Thesis -
3866
Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study
Published 2024“…Results: ICS formation occurred when services had been under sustained pressures with lines of communication and accountability emergent and unclear. …”
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Article -
3867
The role of CD1a in dengue infection
Published 2021“…To investigate the effect of dengue infection on the function of CD1a-reactive T cells, polyclonal blood T cells from patients and controls, and CD1a-autoreactive T cells clone/lines were utilised. The production of IFN-γ and GM-CSF by CD1a-autoreactive T cells was reduced when co-cultured with dengue-infected presenting cells. …”
Thesis -
3868
Development of coherent detector technologies for sub-millimetre wave astronomy observations
Published 2012“…</p> <p>Using the current 16-pixel 350 GHz SIS receiver, HARP-B, we have observed the <sup>12</sup>CO J=3→2 emission lines from two nearby galaxies. An important result we found is that the <sup>12</sup>CO J=3→2 correlates strongly with the 8 μm Polycyclic Aromatic Hydrocarbon emission.…”
Thesis -
3869
Structure and inhibition of novel cyclin-dependent kinases
Published 2015“…Preliminary trials using these relatively non-selective compounds to inhibit CDK16 in melanoma and medulloblastoma cancer cell lines revealed rebastinib as the more efficacious drug causing loss of cell proliferation in the 1-2 micromolar range. …”
Thesis -
3870
Dwelling encounters: migration, diversity and ambivalence in an Istanbul neighborhood
Published 2017“…In this dissertation I apply a novel theoretical approach drawing on the concept of dwelling for understanding how residents of Kumkapı relate to their environment and make sense of it. I propose three lines of argument that unfold sequentially through the organizing structure of the thesis. …”
Thesis -
3871
An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps, an...
Published 2025“…Steady and unsteady casing static pressure measurements were acquired, using pneumatic lines and high-frequency response (∼100 kHz) Kulite pressure transducers, respectively. …”
Journal article -
3872
Key transcriptional regulators of neutrophil function in inflammation
Published 2021“…</p> <p>To investigate the regulatory role of the selected TFs in neutrophils, I utilised HoxB8 myeloid progenitors as a model system for in vitro production of neutrophils and generated stable knockout lines for JUNB, RELB, IRF5, RFX2, KLF6, and RUNX1 in Hoxb8 myeloid progenitors, using the CRISPR/Cas9 mediated system. …”
Thesis -
3873
BRCA1 regulation of breast cancer cell motility
Published 2023“…Time-lapse microscopy of breast cancer cell lines with various BRCA1 backgrounds was employed to evaluate the impact of inhibiting ubiquitin ligase activity. …”
Thesis -
3874
How are cognitive maps formed and encoded in humans?
Published 2024“…In Chapter 4, we find evidence for the latter, with trajectory training resulting in neural encoding of the map that is more similar to separate transitive lines along rows and columns, the extent of which is related to behavioural accuracy. …”
Thesis -
3875
Nanoparticles enhanced laser-induced breakdown spectroscopy for characterisation and discrimination of gemstones
Published 2024“…Results have shown a significant enhancement in spectral features, i.e., the emergence of several new spectral lines of major gemstone elements in the UV-Vis regions of the NELIBS spectra, while the CLIBS spectra were devoid of any meaningful spectral information. …”
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Conference or Workshop Item -
3876
Synthetic, spectroscopic, biological and X-ray crystallographic structural studies on a novel pyridine-nitrogen-bridged dimeric nickel(II) complex of a pentadentate N3S2 ligand
Published 2001“…The anticancer properties of these compounds were also evaluated against Human T-lymphoblastic leukaemia cell lines. The Schiff base exhibits marked cytotoxicity against these cells, but its nickel(II) complex is inactive.…”
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Article -
3877
Empowering Teen Mental Fitness : A Guide for Managing Addiction, Eating Disorders, OCD, and Trauma /
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software, multimedia -
3878
Characterizing dry mass and volume changes in human multiple myeloma cells upon treatment with proteotoxic and genotoxic drugs
Published 2023“…We show that human MM cell lines (RPMI8226, MM.1S, KMS20, and AMO1) increase dry mass upon bortezomib treatment. …”
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Article -
3879
A low-cost, open-source cylindrical Couette rheometer
Published 2024“…As a result, rheometers are typically large, expensive, and require additional infrastructure (e.g., gas lines), rendering them inaccessible for regular use by many individuals, small organizations, and educators. …”
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Article -
3880
Three distinct 3-methylcytidine (m3C) methyltransferases modify tRNA and mRNA in mice and humans
Published 2018“…METTL8, however, modified only mRNA, as determined by biochemical and genetic analyses in Mettl8 null-mutant mice and two human METTL8 mutant cell lines. Our findings provide the first evidence of the existence of m3C modification in mRNA, and the discovery of METTL8 as an mRNA m3C writer enzyme opens the door to future studies of other m3C epitranscriptomic reader and eraser functions.…”
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Journal Article