Targeting the cytochrome oxidases for drug development in mycobacteria by Lee, Bei Shi, Sviriaeva, Ekaterina, Pethe, Kevin

“…The identification of small-molecule inhibitors of the cytochrome bcc-aa3 under numerous experimental conditions reflects the essentiality of the pathway for the optimum growth of M. tuberculosis. Recent findings on the biology of the cytochrome bcc-aa3 as well as the report of the first high-resolution structure of a mycobacterial cytochrome bcc-aa3 complex will help in the characterization and further development of potent inhibitors. …”
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Atomic-scale mechanisms of defect- and light-induced oxidation and degradation of InSe by Kistanov, Andrey A., Cai, Yongqing, Zhou, Kun, Dmitriev, Sergey V., Zhang, Yong-Wei

“…Moreover, under ambient conditions, the splitting of O2 enables the formation of substitutional (apical) oxygen atomic species, which further cause the trapping and subsequent rapid splitting of H2O molecules and ultimately the formation of hydroxyl groups. Our findings uncover the causes and underlying mechanisms of InSe surface degradation via defect-photo-promoted oxidations. …”
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Nanoplasmonic ruler for measuring separation distance between supported lipid bilayers and oxide surfaces by Abdul Rahim Ferhan, Spackova, Barbora, Jackman, Joshua A., Ma, Gamaliel J., Sut, Tun Naw, Homola, Jiri, Cho, Nam-Joon

“…The results indicate that there is a larger separation distance between SLBs and titania surfaces than silica surfaces, and the trend was consistent across three tested lipid compositions. We discuss these findings within the context of the interfacial forces underpinning bilayer–substrate interactions, and the nanoplasmonic ruler strategy provides the first direct experimental evidence comparing SLB separation distances on titania and silica surfaces.…”
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RoboTSP - a fast solution to the robotic task sequencing problem by Suárez-Ruiz, Francisco, Lembono, Teguh Santoso, Pham, Quang-Cuong

“…We discuss the relationship between RTSP and other Traveling Salesman Problem (TSP) variants, such as the Generalized Traveling Salesman Problem (GTSP), and show experimentally that our method finds motion sequences of the same quality but using several orders of magnitude less computation time than existing approaches.…”
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Leveraging nanocrystal HKUST-1 in mixed-matrix membranes for ethylene/ethane separation by Chuah, Chong Yang, Samarasinghe, Samarasinghe Arachchige Sulashi Chathushka, Li, Wen, Goh, Kunli, Bae, Tae-Hyun

“…Then, polyimide-based polymers, ODPA-TMPDA and 6FDA-TMPDA, were chosen as the matrices. Our findings revealed that 20 wt% loading of HKUST-1 was capable of improving C₂H₄ permeability (155% for ODPA-TMPDA and 69% for 6FDA-TMPDA) without excessively sacrificing the C₂H₄/C₂H₆ selectivity. …”
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Mechanical design and performance evaluation of active thermosiphon beam terminal units by Ji, Ke, Cai, Wenjian, Wu, Bingjie, Ou, Xianhua

“…Moreover, the sensible heat ratio (SHR) and heat transfer effectiveness of ATB can reach 42% and 27.3 respectively which validate the feasibility of the proposed terminal unit. The experimental findings provide a guideline for the design and operation of the ATB system.…”
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Take a “selfie” : examining how leaders emerge from leader self-awareness, self-leadership, and self-efficacy by Bracht, Eva M., Keng-Highberger, Fong T., Avolio, Bruce J., Huang, Yiming

“…We critically discuss our findings and provide ideas for future research.…”
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Motivation to lead as mediator of relations between the dark triad, big five, and leadership intention by Kennedy, Jeffrey C., Chan, Kim Yin, Ho, Ringo Moon-Ho, Uy, Marilyn A., Chernyshenko, Oleksander S.

“…Narcissism explains variance in leadership intentions over and above that explained by extraversion; this contrasts with the studies of leader emergence, where the effect of narcissism disappears once extraversion is controlled. Overall, our findings validate the three-factor conceptualization of motivation to lead and illuminate the roles of both bright and dark personality factors in understanding individual desire to attain leadership roles.…”
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Potential ago2/miR-3068-5p cascades in the nucleus accumbens contribute to methamphetamine-induced locomotor sensitization of mice by Liu, Dan, Liang, Min, Zhu, Li, Zhou, Ting-Ting, Wang, Yu, Wang, Rui, Wu, Fei-Fei, Goh, Eyleen Lay Keow, Chen, Teng

“…Knocking down miR-3068-5p, serving as an Ago2-dependent miRNA, strengthened the METH sensitization responses in mice. These findings demonstrated that dysregulated Ago2 in neurons in the NAc is capable of regulating METH sensitization and suggested a potential role of Ago2-dependent miR-3068-5p in METH sensitization.…”
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Remote monitoring of patient respiration with mask attachment—a pragmatic solution for medical facilities by Koh, Vivian Ci Ai, Ang, Yi Yang, Ser, Wee, Tan, Rex Xiao

“…The overall accuracy of the wheeze detection algorithm was 91.9%. The current findings support and suggest the use of the mask attachment in medical facilities.…”
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Superior cooling performance of a single channel hybrid magnetofluidic cooling device by Varma, Vijaykumar Babulalji, Pattanaik, M. S., Cheekati, S. K., Ramanujan, Raju Vijayaraghavan

“…We also developed a simulation model to describe the MFC process; the results are in good agreement with our experimental findings. The high cooling performance of our device was found to be due to high vorticity and mixing. …”
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Do we need ramsey taxation? Our existing taxes are largely corrective by Yan, Eric, Feng, Qu, Ng, Yew-Kwang

“…The empirical test conducted on the data from the World Bank and the International Labor Organization conforms to this theoretical finding. More concretely, when the labor tax increases by 1 standard deviation from the average level, the average working time may be reduced by 1.125%. …”
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Dynamic network service selection in intelligent reflecting surface-enabled wireless systems: game theory approaches by Thanh Van, Nguyen Thi, Luong, Nguyen Cong, Feng, Shaohan, Nguyen, Huy T., Zhu, Kun, Luong, Thien Van, Niyato, Dusit

“…In particular, we have reveal some important finding, for instance, with the memory effect, the users can achieve the utility higher than that without the memory effect.…”
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Consequences of the endless scroll: exploring the relationships between social media news use, doomscrolling, and negative affect by Ting, Sharon Shu Hui, Lim, Kimberly Li Anne, Tan, Joshua Han Wei

“…Collectively, these findings have practical implications for developing strategies to alleviate the negative emotional consequences of doomscrolling.…”
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Revealing the biotoxicity of phosphorene oxide nanosheets based on the villin headpiece by Zhang, Wei, Gou, Yuanyuan, Cheng, Li, Dong, Kaiwei, Sheng, Yijie, Ye, Chao, Yang, Xianqing, Mu, Yuguang

“…Compared with the dispersion interaction, the electrostatic interaction between PO and the protein has a negligible effect on the structural damage of HP35. These findings might shed light on the biological toxicity of PO nanosheets and would be helpful for future potential biomedical applications of PO nanosheets, such as nanodrugs and antibacterial agents.…”
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Construction of quasi-ordered metal-organic frameworks superstructures via colloidal assembly of anisotropic particles for selective organic vapor sensing by He, Yuheng, Bai, Ling, Liu, Baocang, Duan, Hongwei, Zhang, Jun

“…The dynamic reflection spectral patterns exhibited by these superstructures provide valuable insights into the diffusion rates and surface tension characteristics of the target solvents. These findings underscore the potential of MOFs-based superstructure thin films to discriminate between physiochemically similar solvents, opening new avenues for applications in various fields.…”
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3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay by Zhang, Yingqi, Jiang, Fengtao, Zhao, Charles Yunduo, Cho, Ann-Na, Fang, Guocheng, Cox, Charles D., Zreiqat, Hala, Lu, Zu Fu, Lu, Hongxu, Ju, Arnold Lining

“…During the final stage of cancer metastasis, tumor cells embed themselves in distant capillary beds, from where they extravasate and establish secondary tumors. Recent findings underscore the pivotal roles of blood/lymphatic flow and shear stress in this intricate tumor extravasation process. …”
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A human-centred review on maritime autonomous surfaces ships: impacts, responses, and future directions by Li, Xue, Yuen, Kum Fai

“…Future research directions are also proposed and can serve as recommendations for future human-centred research on MASS. The research findings enhance the understanding of seafarer elements in MASS operations and provide policy implications for future seafarer management.…”
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Revolutionizing ELISA: a one-step blocking approach using lipid bilayer coatings by An, Kyongman, Tae, Hyunhyuk, Shin, Jihoon, Bae, Jieun, Han, Sunguck, Choi, Gichan, Kim, Tae-Hoon, Cho, Nam-Joon

“…Taken together, our findings reveal that one-step lipid blocking not only streamlines the ELISA process but also maintains high sensitivity and specificity, providing an efficient, user-friendly, and environmentally friendly alternative to traditional ELISA blockers and a robust platform for rapid diagnostics.…”
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Transformative transmediation: eliciting student self-evaluation of academic writing through the video essay assignment by Frattarola, Angela, Ahn, Hyejeong, Dixon, Ian

“…Specifically, we found that 1) transmediation enabled students to self-evaluate their writing as they repeatedly listened to their voiceovers, found concrete visuals to illustrate their ideas, and edited their work to fit the concise video format; 2) students broke with habitual, less useful revision practices as they were freed from the conventional and grammatical concerns of written academic text and narrated their arguments colloquially in their voiceovers; 3) students exhibited an improved awareness of audience and medium; and 4) students were more enthusiastic with the course due to the novelty of the multimodal assignment. These findings suggest that including a video essay assignment during the drafting process can serve as an effective tool in advancing students’ abilities to evaluate their own academic writing.…”
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