Exploring and Exploiting Ribonuclease 1: from Protein Biochemistry to Protein Engineering by Wralstad, Evans Christian

“…Efforts to establish a zymogen directed toward the coronavirus SARS-CoV-2 are described in two parts of this thesis. In Chapter 3, the main protease 3CLpro of SARS-CoV-2 is enzymologically characterized. …”
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Engineering Mechanical Counter Pressure Spacesuits and Compression Garments: Active Pressurization and Design for Mobility by Kothakonda, Akshay

“…Spacesuits must provide an astronaut with the conditions necessary to survive an EVA for several hours and to enable them to carry out these complex tasks. One of the main factors impeding the effectiveness of EVA operations is the stiffness of the spacesuits, which is inherent in gas pressurized suits. …”
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Sampling from convex sets with a cold start using multiscale decompositions by Narayanan, Hariharan, Rajaraman, Amit, Srivastava, Piyush

“…We show that even with a cold start, the mixing times of these chains are bounded by a polynomial in n and the aspect ratio of the body. Our main technical ingredient is an isoperimetric inequality for K for a metric that magnifies distances between points that are close to the boundary of K. …”
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Rail transit OD matrix estimation and journey time reliability metrics using automated fare data by Chan, Joanne, S.M. Massachusetts Institute of Technology

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友联社主编对马华文艺和马华身份的影响 ：以白垚为个案 = The influence of editors of the Union Cultural Organizational Limited towards Malaysian Chinese literature and identity : a case study of Bai Yao... by 陈茗敏 Tan, Joyce Min Min

“…The huge success and contributions of the Union contributed to the ideology of Malaysian Chinese Literature as the current main focus of literature instead of its American-backed background. …”
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当青春成为最后的乌托邦 ：探析 "小字辈" 文本所影射的文化现象 = When youth becomes the last utopia : a study of the 'tiny texts' cultural phenomena by 王捷灵 Ong, Cerys Jie Ling

“…The paper discerns that the Youth are the main producers and consumers of these texts, which tend to endorse the mentality of seizing “tiny luck” (xiao que xing) while looking upon the "little life" (xiao ri zi) of social and political apathy as an ideal life model. …”
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Loss of caveolin-1 impairs light flicker-induced neurovascular coupling at the optic nerve head by Loo, Jing Hong, Lee, Ying Shi, Woon, Chang Yi, Yong, Victor H. K., Tan, Bingyao, Schmetterer, Leopold, Chong, Rachel S.

“…Intraocular pressure (IOP) remains the main risk factor for this leading cause of blindness. …”
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Great enhancement effect of 20-40 nm Ag NPs on solar-blind UV response of the mixed-phase MgZnO detector by Han, Shun, Xia, Hao, Lu, Youming, Hu, Sirong, Zhang, Dao Hua, Xu, Wangying, Fang, Ming, Liu, Wenjun, Cao, Peijiang, Zhu, Deliang

“…The slight enhancement in UV light intensity from 20 to 40 nm Ag NPs induces multiple tunnel breakdown phenomena within the mixed-phase MgZnO thin film, which is the main reason for the abnormal great enhancement effect on deep UV response of the device, so the recovery speed of the modified device is not influenced. …”
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新加坡福建话马来语及英借词使用情况调查 = Usage of English and Malay loanwords amongst Singapore Hokkien speakers by 张良忆 Teo, Joey Liang Yi

“…The study is divided into two main parts: (1) a questionnaire survey to collect linguistic and personal background information of the speakers and (2) an interview to examine the use of loanwords by Singaporean Hokkien speakers aged 21 and above, using 72 loanwords collected from the Singapore Minnan Dictionary (Xinjiapo Minnan Hua Cidian) coupled with multiple summary questions. …”
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Leakage-resilient secret sharing with constant share size by Tjuawinata, Ivan, Xing, Chaoping

“…The current paper has two main contributions: (i) we obtain leakage-resilient secret sharing schemes with constant share sizes and unbounded numbers of players. …”
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Thermally induced phase separation PVDF membrane fabricated by using NaCl coagulation bath: relation of membrane surface morphology and permeation performance by Chen, Ningyuan, Zhao, Jie, Shi, Lei, Goto, Atsushi, Wang, Rong

“…The PVDF membranes were fabricated using a dope with water insoluble diluent dimethyl phthalate (DMP) as main solvent and water-soluble additives polyethylene glycol 400 (PEG400)/triethylene glycol (TEG) as pore formers. …”
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新加坡淡马锡经验对黑龙江省国企改革与国资监管体系建设的借鉴研究 = Studying and using the experiences of Temasek in Singapore for Heilongjiang Province state-owned enterprises reform and state-owned assets supervi... by 张学伦 Zhang, Xuelun

“…Based on various study approaches, such as meetings and interviews, questionnaire survey, quantitative and qualitative analysis of relevant references and data, the author analyses the basic features and main problems of Heilongjiang Provincial state-owned enterprises and the reform of the state-owned assets supervision administration system. …”
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Photo-driven smart polymers and their molecular self-assembly by Hu, Jinhua

“…Further study was carried out on the star shaped azo-PEGs that exhibit more interesting and complicated self-assembly behaviour. Our main scientific contribution is the mechanism illustrating the extraordinarily large change in vesicle size originated from an isomerization-driven molecular assembly and the substantial transmembrane solvent transport. …”
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Design methodologies for complexity reduction of FIR filters by Faust, Mathias

“…The optimization of the number of adders required in the MCM block has been a main subject of research in many leading publications on circuits and systems, and design automation. …”
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Numerical and experimental investigation of thick composites manufacturing for wind turbines by Ammasai Sengodan, Ganapathi

“…Subsequently, a pressure sensing device consisting of a fiber Bragg grating (FBG) was designed which is capable of measuring in-situ resin pressure with improved sensitivity even at low pressure. The main purpose of this sensor is to validate the developed numerical simulation procedure by measuring the resin pressure at selected location. …”
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Player acceptance of human computation games by Wang, Xiaohui

“…To address the research gap, two main research questions are identified: 1) what are the underlying factors driving HCG acceptance, and 2) how the influences of these driving factors generalize across contexts and time. …”
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Aircraft noise, overheating and poor air quality in London primary schools' classrooms by Montazami, Azadeh

“…Comfortable environment mainly refers to a surrounding atmosphere which is thermally, acoustically, visually, aesthetically, etc. comfortable. …”
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Neuronal control of cardiac excitability in pro-hypertensive states by Larsen, H

“…</p> <p><b>Chapter 7</b> forms the concluding discussion that summarises the main findings of this thesis and attempt to place it in a clinical context, and highlights avenues of further research. …”

Adipose tissue fatty acid composition, serum lipids, and serum alpha-tocopherol in continuous ambulatory peritoneal dialysis patients living on the island of Crete by Nikolakakis, N, Kounali, D, Tornaritis, M, Anastassou, A, Papadakis, E, Kassotakis, G, Kafatos, A

“…Both CAPD patients and controls had been residents of Crete for at least the last 10 years.</p> <br> <p><strong>Main Outcome Measures:</strong> Adipose tissue was aspirated, and a 12-hour fasting blood sample was collected for determination of serum lipid parameters and serum α-tocopherol levels; dietary data from a 3-day recall were recorded.…”

Socioeconomic inequalities in risk of infection with SARS-CoV-2 delta and omicron variants in the UK, 2020-22: analysis of the longitudinal COVID-19 Infection Survey by Razieh, C, Shabnam, S, Dambha-Miller, H, Morris, EJA, Yates, T, Chudasama, Y, Zaccardi, F, Gillies, C, Banerjee, A, Pareek, M, Lacey, B, White, M, Khunti, K, Islam, N

“…</p> <p><strong>Participants</strong> Survey participants recruited from randomly selected households to reflect the UK population (England, Scotland, Wales, and Northern Ireland) were divided into the delta cohort (2 July 2020 to 19 December 2021) and the omicron variant (on or after 20 December 2021), the dominant variants during our study period.</p> <p><strong>Main outcome measures</strong> Incidence rate and incidence rate ratio for the presence of the delta and omicron variants by area level deprivation and occupation sector. …”