Showing 341 - 360 results of 10,580 for search '((pinnae OR (spike OR five)) OR ((((pina OR pin) OR bina) OR link) OR ping))', query time: 0.23s Refine Results
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    Unravelling 2-oxoglutarate turnover and substrate oxidation dynamics in 5-methylcytosine-oxidising TET enzymes by Šimelis, K, Belle, R, Kawamura, A

    Published 2024
    “…Simultaneous detection of substrate and cofactors is difficult, contributing to a poor understanding of the dynamics between substrate oxidation and 2OG decarboxylation activities. Here, we profile 5-methylcytosine (5mC)-oxidising Ten-Eleven Translocation (TET) enzymes using MS and 1H NMR spectroscopy methods and reveal a high degree of substrate oxidation-independent 2OG turnover under a range of conditions. 2OG decarboxylase activity is substantial (>20% 2OG turned over after 1 h) in the absence of substrate, while, under substrate-saturating conditions, half of total 2OG consumption is uncoupled from substrate oxidation. 2OG kinetics are affected by substrate and non-substrate DNA oligomers, and the sequence-agnostic effects are observed in amoeboflagellate Naegleria gruberi NgTet1 and human TET2. …”
    Journal article
  3. 343

    DSIF factor Spt5 coordinates transcription, maturation and exoribonucleolysis of RNA polymerase II transcripts by Kuś, K, Carrique, L, Kecman, T, Fournier, M, Hassanein, SS, Aydin, E, Kilchert, C, Grimes, JM, Vasiljeva, L

    Published 2025
    “…Xrn2 activity is stimulated by Spt5 to ensure efficient degradation of nascent RNA leading to Pol II dislodgement from DNA. …”
    Journal article
  4. 344

    Lasting dynamic effects of the psychedelic 2,5-dimethoxy-4- iodoamphetamine ((±)-DOI) on cognitive flexibility by Sabanovic, M, Lazari, A, Blanco Pozo, M, Tisca, C, Tachrount, M, Martins Bach, A, Lerch, J, Walton, M, Bannerman, D

    Published 2024
    “…Here we show that a single dose of the psychedelic 2,5-dimethoxy-4-iodoamphetamine ((±)-DOI) affects structural brain plasticity and cognitive flexibility in young adult mice beyond the acute drug experience. …”
    Journal article
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    The economic burden of rotavirus hospitalization among children < 5 years of age in selected hospitals in Bangladesh by Ahmed, S, Dorin, F, Satter, SM, Sarker, AR, Sultana, M, Gastanaduy, PA, Parashar, U, Tate, JE, Heffelfinger, JD, Gurley, ES, Khan, JAM

    Published 2021
    “…<p><strong>Methods</p></strong> We estimated the societal costs of children <5 years for hospitalization from rotavirus gastroenteritis (RVGE) and incidences of catastrophic health expenditure. …”
    Journal article
  7. 347
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    Effect of Co on twin formation and magnetic properties of Sm(Fe,Ti,V)12 alloys by Tozman, P, Hrkac, G, Patrick, CE, Staunton, JB, Saito, T, Sasaki, T, Ohkubo, T, Sepehri-Amin, H

    Published 2024
    “…Here we have shown that the addition of Co in Sm(Fe<sub>1-x</sub>Co<sub>x</sub>)<sub>10&ndash;11</sub>M<sub>1&ndash;2</sub>&nbsp;alloys, where&nbsp;<em>M</em>=Ti and V, leads to an increase in twin density. Microstructural characterizations revealed that the atomic arrangement in the twin boundary changes depending on the stabilizing element, which directly influences the local intrinsic magnetic properties. …”
    Journal article
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    Periodontal disease and serum uric acid levels in the absence of metabolic syndrome: is there a link? A study on a sample of Cameroonian adults by Nkeck, JR, Ndjoh, JJ, Meyo Mvondo, GF, Eko Ondoa, M, Takam, O, Mbouna, SFM, Tcheutchoua Nzokou, D, Tchuisseu-Kwangoua, LA, Momo, CBY, Ekouelkoum Ngoude, JX, Chemgne, MI, Ama Moor, VJ

    Published 2024
    “…Conclusion: In individuals without elements of metabolic syndrome, hyperuricemia affects one in five people with PD. There appears to be no link between SUA and overall periodontal status in this population. …”
    Journal article
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    Complete genome sequences of five bacteria isolated from rice plants in a paddy field in Sekinchan, Selangor, Malaysia by Abdul Malek, Ahmad Zuhairi, Mohd Hashim, Amalia, Khairil Mokhtar, Nur Fadhilah, Saidi, Noor Baity, Abu Bakar, Mohd Faizal, Singaram, Nallamai

    Published 2024
    “…This study examines the genome sequences of five endophytic bacterial isolates from the Oryza sativa microbiome to assess their potential as plant bio-inoculants. …”
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  20. 360

    A random-key genetic algorithm-based method for transportation network vulnerability envelope analysis under simultaneous multi-link disruptions by Gu, Y, Ryu, S, Xu, Y, Chen, A, Chan, H-Y, Xu, X

    Published 2024
    “…This study aims to develop an efficient method based on the random key genetic algorithm (RKGA) for determining the TNVE under simultaneous multi-link disruptions. The main features and benefits of the proposed method include: (a) it simultaneously solves the upper- and lower-bound problems at the same time while guaranteeing the feasibility of all solutions in the solution procedure; (b) it improves the computational efficiency to ensure the applicability to real transportation networks; and (c) it can provide a variety of alternative solutions in addition to the single optimal one, which facilitates the derivation of TNVE buffer and identification of sub-important links. …”
    Journal article