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1581
Developing small molecule ligands for the study of bromodomain-histone interactions
Published 2017“…The stability of the dihydroquinaxolinone headgroup was optimised by ring size expansion, which maintained CREBBP affinity and binding mode – the latter of which was confirmed by X-Ray crystallography. …”
Thesis -
1582
Resolution of proteotoxic stress in the endoplasmic reticulum by ubiquitin ligase complexes
Published 2016“…ER-associated degradation (ERAD) oversees protein folding and delivers misfolded proteins for degradation by the proteasome via ubiquitin conjugation mediated by RING-type E3 ubiquitin ligases. An intact ERAD is crucial to cellular homeostasis, as unresolved protein imbalances cause ER stress that ultimately lead to apoptosis. …”
Thesis -
1583
Synthesis and properties of porphyrin nanotubes
Published 2018“…An unprecedented method of ring-stacking of pre-formed 6-porphyrin nanorings is discussed as well as a template-directed procedure. …”
Thesis -
1584
Quality seaport : model building and empirical validation
Published 2010“…The survey was sent out to a total of 350 Freight Forwarders, Shipping Lines and Cargo Owners who are main users of the Singapore Port that we are focusing our study on for simplification purposes. …”
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Final Year Project (FYP) -
1585
涂涂写写 = Alchemy of color and brushwork
Published 2020“…To me, lines and brushworks are meant to define forms, while colors seek to emotionally enrich the image. …”
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Book -
1586
Injectable cell transplantation system for cytokine-based cancer immunotherapy
Published 2009“…The construct was able to exert toxicity to two malignant cell lines, MCF-7 and HepG2, but no effect was observed in HeLa and H1229 cells. …”
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Final Year Project (FYP) -
1587
Evaluation and selection of rice mutants for high yield and quality fodder production
Published 2014“…Evaluation over two locations, mutant lines ML21, ML10, ML4, ML6 and ML9 performed better in terms of yield production compared to other mutants. …”
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Thesis -
1588
Identification of a Gene Signature That Predicts Dependence upon YAP/TAZ-TEAD
Published 2024“…We found that the genes in this signature are TEAD-dependent in several melanoma cell lines, and that their expression strongly correlates with YAP/TAZ activation in human melanomas. …”
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Article -
1589
WHISPERS OF THE WIND /
Published 2024“…From the hazardous trip behind enemy lines to the festive East Asian-esque Meihua; from the kingdom hovering above the clouds to the military-driven Bevattna; from the heterogeneous society of a tunnelled realm to Aithan’s duel with the heir of Tentazoa, every step in his journey uncovers a gem of his past, present, and future. …”
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1590
End-to-end simulation of high-contrast imaging systems: methods and results for the PICTURE mission family
Published 2017“…Simulated science observations of the predicted warm ring around Epsilon Eridani illustrate the performance of both missions.…”
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Preprint -
1591
Comparative analysis of changes in retinal layer thickness following femtosecond laser-assisted cataract surgery and conventional cataract surgery
Published 2024“…The average retinal thickness of the four inner macular ring quadrants was used for comparative analysis. …”
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Article -
1592
Temperature and burning history affect emissions of greenhouse gases and aerosol particles from tropical peatland fire
Published 2017“…Mass spectrometric analysis of organic components indicated that aerosol particles emitted at higher temperatures had more unsaturated bonds and ring structures than that emitted from cooler fires. …”
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Journal Article -
1593
Mechanical and microstructural characteristics of high-strength self-compacting concrete (HSSCC) with optimal silica fume and fly ash cement replacement
Published 2024“…These aspects entailed fresh properties’ verification, slump flow, T500, J-ring, segregation resistance, and compressive strength on newly incorporated properties. …”
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Article -
1594
Nanothermite composites with a novel cast curable fluoropolymer
Published 2022“…Herein, we report the synthesis of a novel cast curable fluoropolymer (FP) with 58 wt% fluorine content produced through the cationic ring opening polymerization of 3-Perfluorohexyl-1, 2-epoxypropane. …”
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Journal Article -
1595
Gold-catalyzed intramolecular animation of alcohol pro-electrophiles as novel synthetic strategies to nitrogen heterocycles
Published 2011“…In Chapter V, gold-catalyzed tandem ring opening/amination of secondary and tertiary 2-tosylaminophenylcyclopropyl carbinols is introduced as an efficient synthetic route to 2,3-dihydro-1H-benzo[b]azepines as well as 2-vinylindolines. …”
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Thesis -
1596
Chris Ryan Extreme : Night Strike /
Published 2013“…Shadowed every step of the way by a ruthless CIA hitman, Bald soon finds that the lines between friend and enemy are blurred, and he'll have to call on all his warrior instincts to stay alive...…”
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1597
Role of angiopoietin-like 4 in tumor growth.
Published 2011“…Herein, by using human tumor tissue arrays, tumor cell lines and human skin tumor samples, we found that elevated ANGPTL4 expression is widespread in most known tumor types. …”
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Thesis -
1598
Dealing, music and youth violence: neighbourhood relational change, isolation and youth criminality
Published 2023“…The study considers the emergence of drill music, county lines and the lowering of the threshold of when weapons are used to explore the isolated social environments so many young people find themselves in. …”
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Monograph -
1599
Study of circulation of traffic agents at the road-side bus-stops
Published 2024“…Thus, this study evaluates factors influencing cyclist behaviour and current bus-stop layouts’ effectiveness, including implemented safety features like blue dash lines, rumble strips, and "Slow" markings. Analysis of bus-stop width and traffic flow highlights significant factors impacting cyclist behaviour, suggesting potential safety enhancements. …”
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Final Year Project (FYP) -
1600
A wireless, battery-free device enables oxygen generation and immune protection of therapeutic xenotransplants in vivo
Published 2024“…Through systematic in vitro studies with primary cell lines and cell lines engineered to secrete protein, we demonstrate device performance in preventing hypoxia in ambient oxygen concentrations as low as 0.5%. …”
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Article