Persistent elevation of intrathecal pro-inflammatory cytokines leads to multiple sclerosis-like cortical demyelination and neurodegeneration by James, Rachel E., Schalks, Renee, Browne, Eleanor, Eleftheriadou, Ioanna, Munoz, Carmen Picon, Mazarakis, Nicholas D., Reynolds, Richard

“…Here we tested the hypothesis that persistent production of these cytokines in the meningeal compartment and diffusion into underlying GM can drive chronic MS-like GM pathology. Lentiviral transfer vectors were injected into the sagittal sulcus of DA rats to deliver continuous expression of TNF + IFNγ transgenes in the meninges and the resulting neuropathology analysed after 1 and 2 months. …”
Get full text

Chrysanthemum-like Au@Polydopamine synthesized using one-pot method and its advantage in immunochromatographic assay by Zhang, Gang-gang, Lai, Xiao-cui, Ding, Neng-shui, Xiong, Qirong, Hou, Shuai, Duan, Hongwei, Lai, Wei-hua

“…Flower-like gold nanoparticle (AuNF) is widely used as a probe. …”
Get full text

Functional characterization of plasmodium falciparum reticulocyte binding like protein homologue 1 (PfRH1) by Yap, Sally Shu Lin

“…One of the protein families involved in invasion, reticulocyte binding like protein homologues (PfRHs) has been suggested to be involved in host cell selection. …”
Get full text

Genes for carnivory : a comparative study on the local duplication of papain-like cysteine proteases in carnivorous plants by Tan, Qiao Wen

“…Thus, the presence of protein degrading enzymes such as papain-like cysteine proteases (PLCPs) in trap fluids is not surprising. …”
Get full text

Bio-inspired Flow Sensing and Prediction for Fish-like Undulating Locomotion: A CFD-aided Approach by Zhou, Han, Hu, Tianjiang, Low, Kin Huat, Shen, Lincheng, Ma, Zhaowei, Wang, Guangming, Xu, Haijun

Get full text
Get full text

Functional comparison of human Adenomatous Polyposis Coli (APC) and APC-like in targeting beta-catenin for degradation by Schneikert, Jean, Chandra, Shree Harsha Vijaya, Ruppert, Jan Gustav, Ray, Suparna, Wenzel, Eva Maria, Behrens, Jürgen

“…Using RNA interference and domain swapping experiments, we show that APCL benefits from the 15R of truncated APC to target β-catenin for degradation, in a process likely involving heterodimerization of the two partners. …”
Get full text
Get full text

GOLDEN2-like1 is sufficient but not necessary for chloroplast biogenesis in mesophyll cells of C4 grasses by Lambret-Frotte, J, Smith, G, Langdale, J

“…In land plants, chloroplast biogenesis is regulated by a family of transcription factors named GOLDEN2-like (GLK). In C4 grasses, it has been hypothesized that genome duplication events led to the sub-functionalization of GLK paralogs (GLK1 and GLK2) to control chloroplast biogenesis in two distinct cell types: mesophyll and bundle sheath cells. …”

Dynamic liquid-liquid interface: applying a spinning interfacial microreactor to actively converge biphasic reactants for the enhanced interfacial reaction by Ng, Li Shiuan, Chong, Carice, Lok, Xin Yi, Pereira, Veronica, Ang, Zhi Zhong, Han, Xuemei, Li, Haitao, Lee, Hiang Kwee

“…Herein, we achieve an efficient interfacial reaction by creating a magnetic-responsive, microscale liquid-liquid interface and exploit its dynamic spinning motion to generate vortex-like hydrodynamic flows that rapidly converge biphasic reactants to the point-of-reaction. …”
Get full text

Finding and performing an efficient rigging production workflow for 3D which can be transferred to different aspects apart from character rigging by Oen, Nicholas Weng Wah

Get full text

Re-thinking arts engagement in COVID-19: findings from a hybrid-delivered participatory arts intervention for Singapore's older adults by Yam, Jodie

Get full text

Characterization on three-dimensional trajectory of disk-like gold-nickel-platinum nanomotor using digital holographic imaging by Hu, Liangxing, Rehman, Shakil, Tao, Kai, Miao, Jianmin

Subjects: Get full text
Get full text

Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells by Fang, Zijian, Chen, Shiqian, Manchanda, Yusman, Bitsi, Stavroula, Pickford, Philip, David, Alessia, Shchepinova, Maria M., Corrêa, Ivan R., Jr., Hodson, David J., Broichhagen, Johannes, Tate, Edward W., Reimann, Frank, Salem, Victoria, Rutter, Guy A., Tan, Tricia, Bloom, Stephen R., Tomas, Alejandra, Jones, Ben

Subjects: Get full text

Effect of solvent state and isothermal conditions on gelation of methylcellulose hydrogels by Joshi, Sunil Chandrakant, Liang, C. M., Lam, Yee Cheong

Subjects: Get full text
Get full text

In situ Kerr and harmonic measurement in determining current-induced effective fields in MgO/CoFeB/Ta by Wong, Qi Ying, Gan, Weiliang, Luo, Fanglin, Lim, Gerard Joseph, Ang, Calvin Ching Ian, Tan, Funan, Law, Wai Cheung, Lew, Wen Siang

Subjects: Get full text

Intrapartum-related perinatal deaths in births planned in midwifery-led settings in Great Britain: findings and recommendations from the ESMiE confidential enquiry by Rowe, R, Draper, ES, Kenyon, S, Bevan, C, Dickens, J, Forrester, M, Scanlan, R, Tuffnell, D, Kurinczuka, JJ

“…Enhancing the safety of Midwifery-led births Enquiry (ESMiE) reviewed the quality of care in pregnancy, labor, birth, and postpartum in births resulting in intrapartum-related deaths in midwifery-led settings and compared the findings with those of MBRRACE-UK.…”

X-Hair: 3D Printing Hair-like Structures with Multi-form, Multi-property and Multi-function by Wang, Guanyun, Ji, Junzhe, Xu, Yunkai, Ren, Lei, Wu, Xiaoyang, Zheng, Chunyuan, Zhou, Xiaojing, Tang, Xin, Feng, Boyu, Sun, Lingyun, Tao, Ye, Li, Jiaji

Get full text

The effect of bonding structure of diamond like carbon (DLC) film with surface nickel coating upon laser annealing by Xu, Naiyun, Tsang, Siu Hon, Tan, Chong Wei, Teo, Hang Tong, Wang, Xincai, Tay, Beng Kang

“…The Raman spectra shows more pronounced change for a-C films with Ni coating than those without Ni coating upon laser annealing, and the Raman features also suggest that the Ni surface coating can enhance formation of the six-ring graphitic-like sp2 ordering. Electrical measurement shows a low resistive characteristic for both set of films due to laser induced conducting sp2 clusters formation.…”
Get full text
Get full text

China's outward foreign direct investments : analysis of its investments, track record to date and likely future trends by Tan, Teck Eng

Get full text

Conditional knock out of N-WASP in keratinocytes causes skin barrier defects and atopic dermatitis-like inflammation by Kalailingam, Pazhanichamy, Tan, Hui Bing, Jain, Neeraj, Sng, Ming Keat, Chan, Jeremy Soon Kiat, Tan, Nguan Soon, Thanabalu, Thirumaran

Get full text
Get full text

A wearable circulator‐like circularly polarised antenna for full‐duplex wireless body area network applications by Thakur, Ajeet, Sharma, Ashwani, Garcia Zuazola, Ignacio Julio

“…A circulator‐like high gain, unidirectional, dual circularly polarised (DCP) wearable antenna with a low specific absorption rate of 0.088 W/kg for 5.8 GHz industrial, scientific, and medical (ISM) band (5.725 − 5.875 GHz) full‐duplex wireless body area network (WBAN) applications is proposed. …”
Get full text