Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Chapter 4 focuses on the site-specific glycosylation occupancy, and N- and O-glycan structures attached to virion derived SARS-CoV-2 spike glycoproteins. This glycan signature was compared to a stabilised prefusion trimeric spike, to a monomeric subunit of spike (S1) and to an antigen of a non-stabilised vaccine candidate, revealing subunit shedding of the S1 glycoprotein for the vaccine candidate. …”

Comparative effects of domain-specific human monoclonal antibodies against LGI1 on neuronal excitability by Sell, J, Rahmati, V, Kempfer, M, Irani, SR, Ritzau-Jost, A, Hallermann, S, Geis, C

“…However, only the LRR-specific mAbs increased the number of action potential firing together with enhanced initial instantaneous frequency and promoted spike-frequency adaptation, which were less pronounced after the EPTP mAb. …”

Effect of hydrophobic soils on infiltration by Tong, Wan Yi

“…The fine sand layer was then replaced by hydrophobic fine sand to study the effect of hydrophobicity on the infiltration. …”
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Multiscale topological indices for the quantitative prediction of SARS CoV-2 binding affinity change upon mutations by Bi, Jialin, Wee, JunJie, Liu, Xiang, Qu, Cunquan, Wang, Guanghui, Xia, Kelin

“…Biologically, protein-protein interactions between SARS-CoV-2 surface spike (S) protein and human ACE2 protein are the key mechanism behind the COVID-19 disease. …”
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Rapid construction of green nanopesticide delivery systems using sophorolipids as surfactants by flash nanoprecipitation by Ma, Enguang, Chen, Kai, Sun, Liang, Fu, Zhinan, Guo, Jiangtao, Liu, Jichang, Zhao, Jigang, Liu, Zhiyong, Lei, Zhigang, Li, Li, Hu, Xiao, Guo, Xuhong

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Imprinting of IgA responses in previously infected individuals receiving bivalent mRNA vaccines (WT and BA.4/BA.5 or WT and BA.1) by Goh, Yun Shan, Fong, Siew-Wai, Hor, Pei Xiang, Loh, Chiew Yee, Tay, Matthew Zirui, Wang, Bei, Salleh, Siti Nazihah Mohd, Ngoh, Eve Zi Xian, Lee, Raphael Tze Chuen, Poh, Xuan Ying, Lee, I. Russel, Rao, Suma, Chia, Po Ying, Maurer-Stroh, Sebastian, Wang, Cheng-I, Leo, Yee Sin, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

“…Results: We found significantly lower fold change in serum binding IgA responses against BA.1, BA.5 and EG.5.1 spike in the bivalent booster group, compared with the monovalent (WT) booster group, following vaccination. …”
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Perceptual distortion analysis for images by Dong, Li

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Synaptic CMOS transistor by Chai, Zhen Hong

“…In this work, electrical measurements were conducted on commercial level TiN/HfO2 gated n-channel MOSFET transistor (with an equivalent oxide thickness of 1.7nm) to demonstrate that it can exhibit some critical synaptic characteristics of a biological synapse such as excitatory and inhibitory postsynaptic current (EPSC and IPSC), short-term plasticity (STP) and long-term potentiation (LTP), metaplasticity, and spike timing dependent plasticity (STDP). The mechanism behind the output characteristic of MOSFET to exhibit synaptic-like response is the charge trapping and de-trapping at defects in the oxide and oxide/semiconductor interface. …”
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A scalable variational inference approach for increased mixed-model association power by Loya, H, Kalantzis, G, Cooper, F, Palamara, PF

“…We developed Quickdraws, a method that increases association power in quantitative and binary traits without sacrificing computational efficiency, leveraging a spike-and-slab prior on variant effects, stochastic variational inference and graphics processing unit acceleration. …”

Soil-water characteristic curves of hydrophobic sand by Tan, Nicole Shi Qi

“…In this project, the effect of hydrophobicity is investigated using fine and coarse sands. Fine sand was made hydrophobic and mixed with either fine or coarse sand such that sand mixtures of hydrophobicity 20%, 50% and 80% by mass were obtained. …”
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Dengue death rate higher among women than men in Bangladesh by Roney, Miah, Mohd Fadhlizil Fasihi, Mohd Aluwi

“…Given the atypical seasonality of the epidemic and the sudden spike in cases early on, it is noteworthy that mosquito and potential hotspot densities were at an all-time high throughout the previous years.…”
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Design and development of extreme learning machine symposium web portal by Chiang, Yu Hui.

“…In recent years, it has been observed that there is a spike in interest in the development of web based conference management systems. …”
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Mean-field approximation for networks with synchrony-driven adaptive coupling by Fennelly, N, Neff, A, Lambiotte, R, Keane, A, Byrne, A

“…In place of the less tractable spike-timing-dependent plasticity, we employ recently validated phase-difference-dependent plasticity rules, which adjust coupling strengths based on the relative phases of θ-neuron oscillators. …”

Investigation of the contribution of bioaerosol loading to indoor PM pollution on university campus in Singapore by Lee, Brandon Jia Hao

“…Fine particles could be mitigated safely for occupants with an electrostatic precipitator and future work could expound on elevated fungi concentrations in an indoor environment and fine particle mitigation strategies.…”
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Interpreting learned feedback patterns in large language models by Marks, L, Abdullah, A, Neo, C, Arike, R, Krueger, D, Torr, P, Barez, F

“…To test this, we train probes to estimate the feedback signal implicit in the activations of a fine-tuned LLM. We then compare these estimates to the true feedback, measuring how accurate the LFPs are to the fine-tuning feedback. …”

Genetic algorithm based deep learning model adaptation for improvising the motor imagery classification by R, Vishnupriya, Robinson, Neethu, M, Ramasubba Reddy

“…Transfer learning methods such as adaptation or fine-tuning can be used on the pre-trained model to improve the performance. …”
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SimSC: a simple framework for semantic correspondence with temperature learning by Li, X, Han, K, Wan, X, Prisacariu, VA

“…We discover that when fine-tuning ImageNet pre-trained backbone on the semantic matching task, L2 normalization of the feature map, a standard procedure in feature matching, produces an overly smooth matching distribution and significantly hinders the fine-tuning process. …”

Driving mechanism development for autonomous hospital bed by Tan, Jia Liang

“…Demand is foreseen to spike and a range of healthcare services that range from acute to community care is necessary for a holistic healthcare system. …”
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Efficient position decoding methods based on fluorescence calcium imaging in the mouse hippocampus by Tu, Mengyu, Zhao, Ruohe, Adler, Avital, Gan, Wen-Biao, Chen, Zhe S.

“…Here, we develop an efficient strategy to extract features from fluorescence calcium imaging traces and further decode the animal's position. We validate our spike inference-free decoding methods in multiple in vivo calcium imaging recordings of the mouse hippocampus based on both supervised and unsupervised decoding analyses. …”
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Electrolyte-gated neuromorphic transistors for brain-like dynamic computing by He, Yongli, Jiang, Shanshan, Chen, Chunsheng, Wan, Changjin, Shi, Yi, Wan, Qing

“…Particularly, dynamics play an essential role in neural spike information processing. Here, we offer a brief review and perspective in the field of electrolyte-gated neuromorphic transistors for brain-like dynamic computing. …”
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