-
6221
“I decide myself” - a qualitative exploration of end of life decision making processes of patients and caregivers through Advance Care Planning
Published 2021“…Results: Participants’ narratives focused on four major themes with 12 subthemes: a) Engagement with Death, factors influencing respondents’ acceptance of ACP; b) Formation of Preferences, the set of concerns influencing respondents’ choice of care; c) Choice of PDM, considerations shaping respondents’ choice of nominated health spokesperson; and d) Legacy Solidification, how ACP is used to ensure the welfare of the family after the patient passes. These findings led to our development of the directive decision-making process framework, which delineates personal and sociocultural factors influencing participants’ decision-making processes. …”
Get full text
Journal Article -
6222
High-performance deep red colloidal quantum well light-emitting diodes enabled by the understanding of charge dynamics
Published 2022“…Furthermore, an active-matrix CQW-LED pixel circuit is demonstrated. The findings imply that the understanding of charge dynamics not only enables high-performance CQW-LEDs and can be further applied to other kinds of nanocrystal LEDs but also is beneficial to the development of CQW-LEDs-based display technology and related integrated optoelectronics.…”
Get full text
Journal Article -
6223
Malaria parasite stress tolerance is regulated by DNMT2-mediated tRNA cytosine methylation
Published 2023“…In this study, we identified the writer of a specific tRNA cytosine methylation site as a new layer of epitranscriptomic regulation in malaria parasites that regulates the translation of a subset of parasite proteins (>400) involved in different metabolic pathways. Our findings give insight into a novel molecular mechanism that regulates P. falciparum response to drug treatment and sexual commitment.…”
Get full text
Journal Article -
6224
Exploring the perceptions of mhealth interventions for the prevention of common mental disorders in university students in Singapore: qualitative study
Published 2023“…The interpretation of our findings shows that students were reluctant to use mental health services because of the fear of stigma and a possible lack of confidentiality. …”
Get full text
Journal Article -
6225
Patients, carers and healthcare providers' perspectives on a patient-owned surveillance system for diabetic foot ulcer care: a qualitative study
Published 2024“…Conclusion: Our study highlighted several barriers and facilitators from patients, carers and HCPs regarding the use of a patient-owned wound surveillance app. These findings demonstrate the potential of digital health and areas to improve and tailor a DFU wound app suitable for implementation in the local population.…”
Get full text
Journal Article -
6226
Fast AES-based universal hash functions and MACs: featuring LeMac and Macs
Published 2024“…In particular, our framework not only takes into account the number of AES-round calls per message block, but also the very important role of XOR operations and the overall scheduling of the computations. We instantiate our findings with two concrete UHF candidates, both requiring only 2 AES rounds per 128-bit message block, and each used to construct two MACs. …”
Get full text
Journal Article -
6227
The effect of temperature on permittivity measurements of aqueous solutions of glucose for the development of non-invasive glucose sensors based on electromagnetic waves
Published 2023“…The accuracy of the analytical expression is shown experimentally to be above 99%. The findings from the study should enable the design of accurate noninvasive glucose monitoring devices based on electromagnetic sensing techniques.…”
Get full text
Article -
6228
Next generation design of floating systems for coastal solar farms
Published 2023“…Experiments on a novel adaptive barrier-mooring system (ABMS) including perimeter pontoons, submerged barriers, clump weights, mooring lines and anchors were conducted to examine the adaptivity of ABMS to a large tidal range as well as its performance on platform stabilization under wave action. …”
Get full text
Thesis-Doctor of Philosophy -
6229
Surface engineering to manipulate solar energy for thermal management
Published 2023“…The main contribution and finding of this work are an effective enthalpy reduction method through applying an external field that could be universally applied to different solar steam generators. …”
Get full text
Thesis-Doctor of Philosophy -
6230
Design and analysis of high torque density machines for aerospace applications
Published 2024“…To substantiate these theoretical analyses and FEA results, experimental measurements are conducted, validating the overall findings. A flux-switching machine with U-V-array permanent magnet arrangement, termed UV-FSPM, is presented in Chapter 4. …”
Get full text
Thesis-Doctor of Philosophy -
6231
Review and empirical analysis of machine learning-based software effort estimation
Published 2024“…Enhanced estimation supports the development of better predictive models for software project time, cost, and staffing needs. The findings aim to guide future research directions and tool development toward the most accurate machine learning approaches for modelling software development effort, costs, and delivery schedules, ultimately contributing to more efficient and cost-effective software projects.…”
Get full text
Article -
6232
The design and development of a multimedia reading application for pre-schoolers as a foundation in the area of TVET
Published 2025“…Professionals who believe that this multimedia application is useful as one of the self-learning mediums have responded favourably to the study's findings about how this multimedia application functions in terms of assisting pre-schoolers in learning to read from the aspects of content design, interaction, and interface. …”
Get full text
Article -
6233
Two-Dimensional MXene as a Promising Adsorbent for Trihalomethanes Removal: A Density-Functional Theory Study
Published 2024“…Notably, THs such as trichloromethane (CHCl<sub>3</sub>), bromide-chloromethane (CHBrCl<sub>2</sub>), and dibromochloromethane (CHBr<sub>2</sub>Cl) demonstrate the highest TDM values, indicating substantial changes in electronic and optical parameters, with TDM values of 16.363, 15.998, and 16.017 Debye, respectively. These findings highlight the potential of the MXene-Cl layer as an effective adsorbent and detector for CHF<sub>3</sub>, CHClF<sub>2</sub>, CHCl<sub>3</sub>, CHBrCl<sub>2</sub>, and CHBr<sub>2</sub>Cl. …”
Get full text
Article -
6234
Selective fluoride removal from groundwater using CNT-CeO2 electrodes in capacitive deionization (CDI)
Published 2024“…A carbon nanotube-CeO2 (CNT-CeO2) electrode is employed for the electro-sorption of fluoride ions. Our findings are compelling: when processing a mixed F−/Cl− solution comprising 10 mg/L F− and 100 mg/L Cl−, the CNT-CeO2 electrode is seen to reduce the concentration of F− ions to 1.5 mg/L in just 150 min, amounting to an 85 % F− removal efficiency, while the Cl− removal efficiency remains below 2 %. …”
Get full text
Article -
6235
Advancing healthcare with artificial intelligence: diagnostic accuracy of machine learning algorithm in diagnosis of diabetic retinopathy in the Brazilian population
Published 2024“…Conclusions A large database showed that this deep learning algorithm was accurate in detecting referable DR. This finding aids to universal healthcare systems like Brazil, optimizing screening processes and can serve as a tool for improving DR screening, making it more agile and expanding care access.…”
Get full text
Article -
6236
Regulation of the hif-1-dependent hypoxic stress response by C. elegans
Published 2024“…Secondly, we found that loss of the neprilysin metallopeptidase, nep-2, suppressed the egl-9 Egl phenotype through the degradation of multiple neuropeptides including the known NEP-2 target SNET-1. Our findings reveal two different pathways that function downstream of egl-9 to regulate aspects of the hypoxic stress response, both providing a new pathway with which to study the neuromuscular control of egg laying using NEP-2, and critically showing the integration of the evolutionarily conserved hypoxic-stress response and nonsense-mediated decay pathways.…”
Get full text
Thesis -
6237
Mesoscale Brain Mapping: Bridging Scales and Modalities in Neuroimaging – A Symposium Review
Published 2024“…Many CMM faculty presented or participated in a panel discussion, thus contributing to the dissemination of both the technologies they have developed under the auspices of the CMM and the findings they have obtained using those technologies. …”
Get full text
Article -
6238
Visual Acuity Outcomes and Influencing Factors in a Cohort of UK Real-World Diabetic Macular Oedema Patients During the First Two Years of Anti-VEGF Treatment
Published 2025“…An elder age, a better baseline VA, low annual injection numbers (<5), and less frequent injection intervals (≥12 weeks) were negatively associated with ISVA success in the first two years. These findings have implications for managing patient expectations, allocating resources, and understanding DMO clinical management.…”
Get full text
Article -
6239
-
6240
Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore
Published 2020“…Conclusions: Overall, our findings extend our understanding of the molecular and structural evolution of influenza virus strains in Singapore within the global context of these dynamic viruses.…”
Get full text
Journal Article