A signal through the noise: accurate determination of hydrogen atom positions in crystal structures and optimisation of Laue neutron diffraction methods by Sackman, GA

“…This focuses on:</p> <p>Recommendations for the efficient collection of Laue neutron data, in order to optimise the data set completeness and awarded beam-time; strategic considerations for how to best answer the scientific question(s) at hand in a Laue neutron experiment, whilst planning against future contingencies; improving methods for crystal packing and shipping, particularly for air and moisture sensitive materials; discussing issues arising from ice forming on the crystal during a Laue neutron diffraction experiment, and methods for minimising this problem; more effectively modelling disorder using ring shapes, in the crystallographic refinement package CRYSTALS; providing rationale for Laue neutron specific checkCIF comments.…”

Developing small molecule ligands for the study of bromodomain-histone interactions by Brand, M

“…The stability of the dihydroquinaxolinone headgroup was optimised by ring size expansion, which maintained CREBBP affinity and binding mode – the latter of which was confirmed by X-Ray crystallography. …”

Resolution of proteotoxic stress in the endoplasmic reticulum by ubiquitin ligase complexes by Lari, F

“…ER-associated degradation (ERAD) oversees protein folding and delivers misfolded proteins for degradation by the proteasome via ubiquitin conjugation mediated by RING-type E3 ubiquitin ligases. An intact ERAD is crucial to cellular homeostasis, as unresolved protein imbalances cause ER stress that ultimately lead to apoptosis. …”

Synthesis and properties of porphyrin nanotubes by Haver, R

“…An unprecedented method of ring-stacking of pre-formed 6-porphyrin nanorings is discussed as well as a template-directed procedure. …”

Amino-functionalised β-diketiminate ligands (N-nacnacs): Synthesis and coordination chemistry with Main Group elements by Huan, D

“…On the other hand, metathesis reactions of (<b>1-Dipp</b>)SiCl with sources of H- or tBuO- are found to result in a ring contraction process, generating five-membered aza-butadienyl SiIV-complexes of the form (<b>5-Dipp</b>)Si(NDipp)R (R = H, ^tBuO). …”

End-to-end simulation of high-contrast imaging systems: methods and results for the PICTURE mission family by Douglas, Ewan S., Hewawasam, Kuravi, Mendillo, Christopher B., Cahoy, Kerri L, Cook, Timothy A., Finn, Susanna C. Finn, Howe, Glenn A., Kuchner, Marc, J., Lewis, Nikole K., Marinan, Anne D., Mawet, Dimitri, Chakrabarti, Supriya

“…Simulated science observations of the predicted warm ring around Epsilon Eridani illustrate the performance of both missions.…”
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Comparative analysis of changes in retinal layer thickness following femtosecond laser-assisted cataract surgery and conventional cataract surgery by Surl, Dongheon, Kim, Seungmin, Kim, Sangyeop, Kim, Tae-Im, Seo, Kyoung Yul, Jun, Ikhyun

“…The average retinal thickness of the four inner macular ring quadrants was used for comparative analysis. …”
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Transient prediction of nanoparticle-laden droplet drying patterns through dynamic mode decomposition by Tanis-Kanbur, Melike Begum, Kumtepeli, Volkan, Kanbur, Baris Burak, Ren, Junheng, Duan, Fei

“…The developed data-driven approach has also achieved the acceptable prediction for the droplet diameter with less than 0.13% error and a coffee-ring thickness over a range of 2.0 to 6.7 μm. Moreover, the proposed machine learning algorithm can recognize the volume of the droplet liquid and the transition of the drying regime from one to another according to the predicted contact line and the droplet height.…”
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Characterization of the biosynthetic gene cluster and shunt products yields insights into the biosynthesis of balmoralmycin by Ma, Guang-Lei, Xin, Lingyi, Liao, Yanghui, Chong, Zhi-Soon, Candra, Hartono, Pang, Li Mei, Lee, Sean Qiu En, Gakuubi, Martin Muthee, Ng, Siew Bee, Liang, Zhao-Xun

“…Four of the coproducts (compounds 528) are novel compounds that feature a highly oxygenated or fragmented lactone ring, and three of them (compounds 325) exhibited cytotoxicity against the human pancreatic cancer cell line MIA PaCa-2 with IC50 values ranging from 0.9 to 1.2 mg/mL. …”
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Temperature and burning history affect emissions of greenhouse gases and aerosol particles from tropical peatland fire by Kuwata, Mikinori, Kai, Fuu Ming, Yang, Liudongqing, Itoh, Masayuki, Gunawan, Haris, Harvey, Charles F.

“…Mass spectrometric analysis of organic components indicated that aerosol particles emitted at higher temperatures had more unsaturated bonds and ring structures than that emitted from cooler fires. …”
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Mechanical and microstructural characteristics of high-strength self-compacting concrete (HSSCC) with optimal silica fume and fly ash cement replacement by Aliyu Azare, Ahmed, Mohd Haziman, Wan Ibrahim, Faisal Alshalif, Alshalif, Putra Jaya, Ramadhansyah, Nindyawati, Nindyawati

“…These aspects entailed fresh properties’ verification, slump flow, T500, J-ring, segregation resistance, and compressive strength on newly incorporated properties. …”
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Nanothermite composites with a novel cast curable fluoropolymer by Nie, Hongqi, Tan, Li Ping, Pisharath, Sreekumar, Hng, Huey Hoon

“…Herein, we report the synthesis of a novel cast curable fluoropolymer (FP) with 58 wt% fluorine content produced through the cationic ring opening polymerization of 3-Perfluorohexyl-1, 2-epoxypropane. …”
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Sessile droplet evaporation on patterned surfaces by Ng, Aaron Chin Liang

“…With a bigger particle size, the coffee-ring pattern becomes less dominant which slowly transitions into a uniform pattern. …”
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Gold-catalyzed intramolecular animation of alcohol pro-electrophiles as novel synthetic strategies to nitrogen heterocycles by Prasath Kothandaraman

“…In Chapter V, gold-catalyzed tandem ring opening/amination of secondary and tertiary 2-tosylaminophenylcyclopropyl carbinols is introduced as an efficient synthetic route to 2,3-dihydro-1H-benzo[b]azepines as well as 2-vinylindolines. …”
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Study of cascade failures of power grids by Ng, Jason Wei Long.

“…Complex networks have been the recent model that researchers adopted so as to study the power grid in greater detail. Making use of the ring network topology, the power grid is then modeled into a complex network. …”
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Mechanics of fracture and flexure in Antarctic ice sheets and ice shelves by Zhang, H

“…In grounding zones and floating ice shelves, ice fracturing is often associated with flexure modulated by ocean tides and subglacial water flow, as well as stresses created by shearing, such as pinning points. Fracture and flexure significantly affect the vulnerability of Antarctic ice shelves to hydrofracturing and, by altering buttressing effects, the mass balance of the entire Antarctic Ice Sheet. …”

Synthesis of α-methylene-δ-valerolactone and its selective polymerization from a product mixture for concurrent separation and polymer production by Khechfe, Alexander A, Eckstrom, Francesca D, Chokkapu, Eswara Rao, Baston, Lucas A, Liu, Bowei, Chen, Eugene Y-X, Román-Leshkov, Yuriy

“…Using a model mixture of 30 wt% of MVL in DVL, vinyl-addition polymerization converted MVL to the corresponding vinyl polymer (PMVL)VAP in 98% yield, while DVL was recovered in 96% yield by distillation. Alternatively, ring-opening polymerization of the same mixture resulted in a DVL/MVL copolyester and separatable vinyl homopolymer P(MVL)VAP.…”
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Biochemical Analysis of Poly(ethylene terephthalate) Film Degradation Kinetics of Engineered IsPETase Variants by Zhong-Johnson, En Ze Linda

“…I developed a kinetic assay based on spectrophotometric measurements of UVabsorbance of the products in the reaction supernatant, as degradation products harboring the benzene ring will absorb between 240-280 nm. The method was found to be reliable to obtain relative measurements of initial reaction rates but cannot be used to determine the absolute concentration of products in the supernatant. …”
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Synthesis of biomimetic co-polypeptides with tunable degrees of phosphorylation by Lipik, Vitali, Zhang, Lihong, Miserez, Ali

“…Here, we present a co-polypeptide synthesis strategy based on the Ring-Opening Polymerization (ROP) of N-carboxyanhydrides (NCAs), followed by controlled phosphorylation of serine (Ser) residues. …”
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Tunable quantum cascade lasers for midinfrared spectroscopic sensing by Li, Jinghao

“…Finally, we design a novel tunable QCL based on coupled ring resonator filters. The fabricated device achieves a quasi-continuous tuning range of ~ 18 cm^-1 around 7.4 µm by varying heatsink temperature.…”
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