Evaluating new malaria vaccine candidates by Noé, A

“…Liver-resident memory CD8+ T cells (TRM) are necessary for protection against rodent malaria by this vaccine regimen. Ultimately, to most faithfully assess immunological responses by these local, specialised, hepatic T cells, periodic liver sampling is necessary. …”

Turbulence-induced secondary flows in straight open channel with imposed transverse bed non-uniformities by Wang, Zhiqian

“…This study also discusses effects of cellular secondary flows on the concentration distribution of suspended sediment.…”
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The prevention and management of chronic kidney disease among patients with metabolic syndrome by Zhu, D, Judge, PK, Wanner, C, Haynes, R, Herrington, WG

“…In addition, statin-based regimens lower low-density lipoprotein cholesterol and reduce the risk of atherosclerotic disease (with no clinically meaningful effect on kidney outcomes). …”

Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. …”

Dynamic friction model for tendon-sheath actuated surgical robots : modelling and stability analysis by Tjahjowidodo, Tegoeh, Lau, Michael Wai Shing, Phee, Soo Jay, Do, T. N.

“…In addition, transition between two regimes is guaranteed to be smooth without using any switching functions and it permits an arbitrary configuration of sheath, i.e. helical and spatial shape. …”
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Structure of mushy layers grown from perfectly and imperfectly conducting boundaries. Part 1. Diffusive solidification by Hitchen, JR, Wells, AJ

“…For an isothermal boundary we characterise different growth regimes depending on a concentration ratio, which can also be viewed as characterising the ratio of composition-dependent freezing point depression versus the temperature difference across the mushy layer. …”

Genomic profiling of mycobacterium tuberculosis strains, Myanmar by Aung, Htin Lin, Nyunt, Wint Wint, Fong, Yang, Biggs, Patrick J., Winkworth, Richard C., Lockhart, Peter J., Yeo, Tsin Wen, Hill, Philip C., Cook, Gregory M., Aung, Si Thu

“…Introducing new oral drugs to replace those currently used in treatment regimens for multidrug-resistant TB will also be useful for treating TB in Myanmar.…”
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Neap-spring tidal effects on dissolved oxygen in two Malaysian estuaries by Nelson, Bruce W., Sasekumar, A., Ibrahim, Zelina Z.

“…These oxygen minima are attributed to the high oxygen demand of sediment that rests on the bottom during neap tides and is resuspended during spring tides. …”
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Surface Friction and Spectroscopic Probes of New Physics with Trapped Ions by Counts, Ian T.

“…By varying transport speed and corrugation depth, experimental signatures of both regimes are measured and used to write a predictive Boltzmann model. …”
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Strongly out-of-equilibrium simulations for electron Boltzmann transport equation using modal discontinuous Galerkina approach by Singh, Satyvir, Battiato, Marco

“…Ultimately, these results predict that the modal DG approach is particularly effective in treating the strongly out-of-equilibrium regimes encountered like in ultrafast transport dynamics.…”
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MU'TAQAL Machine: Power, Gender and Identity in Egypt's Political Prisons, 1948-1981 by Ashmawi, HE

“…<p>This thesis charts the history and evolution of a mass-incarcerating regime of detention, disappearance and torture in Egypt between 1948 and 1981. …”

Psychosocial predictors of self-reported medical adherence in patients with heart failure over 6 months : an examination of the influences of depression, self-efficacy, social supp... by Shen, Biing-Jiun, Maeda, Uta

“…Background Poor adherence to medical regimens is a serious problem that interferes with heart failure (HF) patients’ disease management and contributes to poor clinical outcomes. …”
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Clostridium difficile bacteriophage finding under normal and iron-limited conditions for the isolation of potential siderophore receptor-specific phages by Lim, Edsel Yong Xun

“…Phage therapy, known for its specificity of action, has emerged as a promising candidate for combating CDI, offering the potential to circumvent gut microbiome dysbiosis associated with conventional antibiotic regimens. However, research on Clostridium difficile (C. difficile) phage hunting has been relatively limited. …”
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The role of SPRTN protease in colorectal cancer chemotherapy by Peron, C

“…The first-line treatment of metastatic colorectal cancer (mCRC) is frequently based on combination chemotherapeutic regimens, where 5-fluorouracil is either associated with irinotecan (FOLFIRI) or oxaliplatin (FOLFOX). …”

Exploring the therapeutic potential of 5-fluorouracil-loaded calcium carbonate nanoparticles combined with natural compound thymoquinone for colon cancer treatment by Deng, Xi, Yang, Zhongming, Chan, Kim Wei, Abu Bakar, Md Zuki

“…These results provide evidence for 5FU-CaCO3np as a novel regimen against colon cancer. Combining 5FU-CaCO3np and TQ may offer a new perspective for colon cancer therapy.…”
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Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish by Goh, Boon Chong, Larsson, Simon, Dam, Linh Chi, Ling, Sharon Yan Han, Chua, Patrina Wei Lin, Abirami, R., Singh, Samsher, Ong, Ernest Jun Long, Teo, Jeanette W. P., Ho, Peiying, Ingham, Philip William, Pethe, Kevin, Dedon, Peter C.

“…Because of its extensive innate resistance to numerous antibiotics, treatment options are limited, often resulting in poor clinical outcomes. Current treatment regimens usually involve a combination of antibiotics, with clarithromycin being the cornerstone of NTM treatments.…”
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Enhancing spectrum efficiency through hybrid-duplex systems for aeronautical communications by Tan, Ernest Zheng Hui

“…Through the various performance analysis, the benefits of HBD systems over half-duplex (HD) systems at low signal-to-noise ratio (SNR) regimes are highlighted. The major contributions of this thesis are further elaborated below. …”
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Effects of Tip Clearance and Surface Roughness on Small-Scale Turbopump Impeller Performance by Ruecker, Kinjal A. L.

“…This lowers the effective tip clearance that separates the flow regimes. The contribution of blade tip leakage loss to total impeller loss decreases by up to 22% for surface roughness increased from an Rₐ value of 1 µm to 10 µm. …”
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Design and development of bio-medical devices using rapid prototyping techniques by Phua, Kenneth Khiang Song.

“…Many drug regimes must be carefully dosed as they are either too complicated to be self –administered or face low compliance by the patients themselves. …”
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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by McIlroy, G, Gaskell, C, Jackson, A, Yafai, E, Tasker, R, Thomas, C, Fox, S, Boucher, R, Ghebretinsea, F, Harrison, C, Mead, AJ, McMullin, MF

“…FEDORA uses a within-patient dose escalation regimen to ensure each patient reaches a personalised dose combination that is acceptable. …”