Evaluating new malaria vaccine candidates by Noé, A

“…Liver-resident memory CD8+ T cells (TRM) are necessary for protection against rodent malaria by this vaccine regimen. Ultimately, to most faithfully assess immunological responses by these local, specialised, hepatic T cells, periodic liver sampling is necessary. …”

Evaluation of subconjunctival liposomal steroids for the treatment of experimental uveitis by Wong, Chee Wai, Czarny, Bertrand, Metselaar, Josbert M., Ho, Candice, Ng, Si Rui, Barathi, Amutha Veluchamy, Storm, Gert, Wong, Tina T.

“…The current gold standard for treatment is topical steroids, but low ocular bioavailability and compliance issues with the intensive dosing regimen limit the efficacy of this treatment. Liposomes as a drug delivery system may help to overcome these problems. …”
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Localization and motion planning of mobile robots by Dai, Yunxiang

“…Afterward, a novel reference path segment generation and switching mechanism are proposed to bridge the perception with the low-level controller. …”
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Exploring the therapeutic potential of 5-fluorouracil-loaded calcium carbonate nanoparticles combined with natural compound thymoquinone for colon cancer treatment by Deng, Xi, Yang, Zhongming, Chan, Kim Wei, Abu Bakar, Md Zuki

“…These results provide evidence for 5FU-CaCO3np as a novel regimen against colon cancer. Combining 5FU-CaCO3np and TQ may offer a new perspective for colon cancer therapy.…”
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Structural and mechanistic insights into the Rel protein of Mycobacterium tuberculosis by Singal, Bharti

“…The MtRel NTD in the presence of TGS domain showed almost similar synthetic activity as of MtRel NTD and approximately 3 fold higher than that of MtRel showing auto-inhibition by rest of the C-terminus MtRel segment. The MtRel ACT structure was determined as a dimer and the oligomeric state was further confirmed using SAXS. …”
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Associations between health literacy and health care utilization and mortality in patients with coexisting diabetes and end-stage renal disease : a prospective cohort study by Griva, Konstantina, Loong, Russel K. L., Nandakumar, Mooppil, Rajeswari, Moothathamby, Khoo, Eric Y. H., Lee, Vanessa Y. W., Kang, Augustine W. C., Osborne, Richard H., Brini, Stefano, Newman, Stanton P.

“…Patients with diabetes (DM) comprise the fastest growing segment of patients with end-stage renal disease (ESRD). …”
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Sustaining antimicrobial stewardship in a high-antibiotic resistance setting by Ng, Tat Ming, Heng, Shi Thong, Chua, Boon Hou, Ang, Li Wei, Tan, Sock Hoon, Tay, Hui Lin, Yap, Min Yi, Quek, Jason, Teng, Christine B., Young, Barnaby Edward, Lin, Ray, Ang, Brenda, Lee, Tau Hong, Lye, David C.

“…Design, Setting, and Participants: This cohort study used an interrupted time series with segmented regression analysis of data from January 2007 to December 2018. …”
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Fedratinib combined with ropeginterferon alfa-2b in patients with myelofibrosis (FEDORA): study protocol for a multicentre, open-label, Bayesian phase II trial by McIlroy, G, Gaskell, C, Jackson, A, Yafai, E, Tasker, R, Thomas, C, Fox, S, Boucher, R, Ghebretinsea, F, Harrison, C, Mead, AJ, McMullin, MF

“…FEDORA uses a within-patient dose escalation regimen to ensure each patient reaches a personalised dose combination that is acceptable. …”

May measurement month 2022: an analysis of blood pressure screening findings from Sierra Leone by Jalloh, MB, Williams, CEE, Jegede, OG, Malijan, GMB, Naveed, A, Kanu, A, Bah, AK, Jalloh, F, Jalloh, A, Faulkner, MMJ, Agboola, K, Baldeh, M, Russell, JBW, Oladapo, OO

“…Notably, 42.9% of the participants with known hypertension did not adhere to their antihypertensive medication regimen, citing cost, availability, side effects, and forgetfulness as common reasons. …”

Repurposing nitroxoline to address antibiotic resistance in the production of poultry for consumption by Zhou, Y

“…<em>In-vivo</em> evaluation (Chapter 5) established an optimal dosage regimen (100 mg/kg of NTX in feed) for treating <em>Salmonella</em> infections in poultry without promoting the development of resistance. …”

Cytisine versus varenicline for smoking cessation in a primary care setting: a randomized non-inferiority trial by Oreskovic, T, Percac-Lima, S, Ashburner, JM, Tiljak, H, Rifel, J, Klemenc Ketiš, Z, Oreskovic, S

“…Given the much lower cost of cytisine treatment, its lower rate of adverse events, and higher feasibility (but its likely lower effectiveness with the standard dosage regimen), future analyses should assess the cost-effectiveness of the two treatments for health policy considerations.…”

Synthesizing photorealistic images with deep generative learning by Zheng, Chuanxia

“…To achieve this goal, a new pipeline is presented that interleaves the two tasks of instance segmentation and scene completion through multiple iterations, solving for objects in a layer-by-layer manner. …”
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Mechanically durable and damage resilient dielectric elastomer actuators by Tan, Matthew Wei Ming

“…By tuning hard-to-soft segment ratios and molecular weights of polydiols, carboxyl polyurethanes (PULM0) attained large mechanical toughness (96.5 MJ m-3) and puncture resistance. …”
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Studies on the assessment of abdominal aortic aneurysm rupture risk by Canchi, Tejas

“…This was done using a combination of in-house segmentation codes and commercial finite element analysis (FEA) software. …”
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Tracking and detecting objects in image sequence by Wang, Li

“…Then, a so-called “split-merge” approach is proposed to over-segment a foreground region into subregions and then cluster them into a number of object regions by using the proposed boundary based similarity metric. …”
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Security for automotive electrical/electronic (E/E) architectures by Mundhenk, Philipp

“…These internal networks consist of specialized automotive components, are often not sufficiently segmented or secured, and messages are transmitted unencrypted. …”
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Pnictogen-halide semiconductors for photovoltaics by Liu, P

“…Convolutional Neural Network (CNN) models were used to evaluate the density of pinholes in the scanning electron microscopy images, and the Segment Anything Model (SAM) was used to separate different regions within the images. …”

Towards robust sensing and recognition : from statistical learning to transfer learning by Yang, Jianfei

“…These algorithms can be further applied to improving the generalization abilities of deep models for WiFi-based sensing and visual sensing including object recognition, object detection, sentiment segmentation and person re-identification.…”
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