Drug interaction between acetyltanshinone IIA and rapamycin in breast cancer cells by Wong, De Pin

“…Developing in vitro drug combination study is essential for the development of new and effective combination regimens. In this project, the objective is to investigate the synergistic potential between two anti breast cancer agent, rapamycin and acetyltanshinone IIA (ATA) in breast cancer cells. …”
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Criteria for Crack Formation and Air Invasion in Drying Colloidal Suspensions by Lilin, Paul, Bischofberger, Irmgard

“…We show that the pressure inside the deposit controls both the onset of crack formation and the onset of air invasion. Two distinct regimes of air invasion occur, which we can account for using the same model that further provides a quantitative criterion for the crossover between the two regimes.…”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Further, to augment efficacy, combination regimens were also explored. Results We confirm that only ACK2 inhibits SCF binding fully and prevents HSC proliferation in vitro. …”
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A comparative analysis of missing data imputation techniques on sedimentation data by Loh, Wing Son, Ling, Lloyd, Chin, Ren Jie, Lai, Sai Hin, Loo, Kar Kuan, Seah, Choon Sen

“…A comparative analysis on the missing fine sediment data imputation performance was made based on four different techniques, namely the k-Nearest Neighbourhood (k-NN), Support Vector Regression (SVR), Multiple Regression (MR), and Artificial Neural Network (ANN), under the single imputation (SI) and multiple imputation (MI) regimes. Across different missing data proportions (10%-50%), the ANN demonstrated optimal results with consistent performance metrics recorded over both SI and MI regimes. …”
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Experimental study on sediment clump by Yang, Yang

“…A group of dense particles released instantaneously into stagnant ambient water is generally studied as thermal-like formation, experiences the classical three regimes of transition, namely the acceleration, thermal and dispersive regimes (Wilkinson & Rahimipour 1992). …”
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Dynamic friction model for tendon-sheath actuated surgical robots : modelling and stability analysis by Tjahjowidodo, Tegoeh, Lau, Michael Wai Shing, Phee, Soo Jay, Do, T. N.

“…In addition, transition between two regimes is guaranteed to be smooth without using any switching functions and it permits an arbitrary configuration of sheath, i.e. helical and spatial shape. …”
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Structure of mushy layers grown from perfectly and imperfectly conducting boundaries. Part 1. Diffusive solidification by Hitchen, JR, Wells, AJ

“…For an isothermal boundary we characterise different growth regimes depending on a concentration ratio, which can also be viewed as characterising the ratio of composition-dependent freezing point depression versus the temperature difference across the mushy layer. …”

Shedding Light on Chemoresistance: The Perspective of Photodynamic Therapy in Cancer Management by Viana Cabral, Fernanda, Quilez Alburquerque, Jose, Roberts, Harrison James, Hasan, Tayyaba

“…Photodynamic therapy (PDT) has emerged as a promising photochemistry-based approach to address chemoresistance in cancer regimens. PDT not only induces cell death but also primes surviving cells, enhancing their susceptibility to subsequent therapies. …”
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Disposition kinetics of tylosin administered intravenously and intramuscularly in Desert Sheep and Nubian Goats by Taha, A.A., Elsheikh, H.A., Khalafalla, A.E., Osman, I. A. M., Abdullah, A. Salam

“…The present study has shown that, despite the significant differences in some of the drug pharmacokinetic parameters between sheep and goats for the i.v. route, identical intravenous and intramuscular dosage regimens of tylosin may be recommended for the two species.…”
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Surface Friction and Spectroscopic Probes of New Physics with Trapped Ions by Counts, Ian T.

“…By varying transport speed and corrugation depth, experimental signatures of both regimes are measured and used to write a predictive Boltzmann model. …”
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Strongly out-of-equilibrium simulations for electron Boltzmann transport equation using modal discontinuous Galerkina approach by Singh, Satyvir, Battiato, Marco

“…Ultimately, these results predict that the modal DG approach is particularly effective in treating the strongly out-of-equilibrium regimes encountered like in ultrafast transport dynamics.…”
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MU'TAQAL Machine: Power, Gender and Identity in Egypt's Political Prisons, 1948-1981 by Ashmawi, HE

“…<p>This thesis charts the history and evolution of a mass-incarcerating regime of detention, disappearance and torture in Egypt between 1948 and 1981. …”

In Vivo RNA Delivery to Hematopoietic Stem and Progenitor Cells via Targeted Lipid Nanoparticles by Shi, Dennis, Toyonaga, Sho, Anderson, Daniel G

“…However, these therapies have several limitations owing to the manufacturing complexities and toxicity resulting from required conditioning regimens. Here, we developed a c-kit (CD117) antibody-targeted lipid nanoparticle (LNP) that, following a single intravenous injection, can deliver RNA (both siRNA and mRNA) to HSCs in vivo in rodents. …”
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Behind every domain there is a shift: adapting distortion-aware vision transformers for panoramic semantic segmentation by Zhang, J, Yang, K, Shi, H, ReiB, S, Peng, K, Ma, C, Fu, H, Torr, PHS, Wang, K, Stiefelhagen, R

“…Extensive experiments are conducted, which cover indoor and outdoor scenarios, and each of them is investigated with Pin2Pan and Syn2Real regimens. Trans4PASS+ achieves state-of-the-art performances on four domain adaptive panoramic semantic segmentation benchmarks. …”

Knowledge and practice regarding medication use among elderly with chronic diseases in Felda Tembangau 2, Kemayan, Pahang by Farid, Aina Natasha Mohd

“…The elderly population, defined as those aged 60 and above, faces unique challenges in managing chronic diseases due to physiological changes, limited access to healthcare information, and barriers in understanding and adhering to medication regimens. The aim of this study was to determine the levels of knowledge and practice regarding medication use among elderly with chronic diseases in FELDA Tembangau 2, Kemayan, Pahang and to explore the correlation between these two variables. …”
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Enhancing spectrum efficiency through hybrid-duplex systems for aeronautical communications by Tan, Ernest Zheng Hui

“…Through the various performance analysis, the benefits of HBD systems over half-duplex (HD) systems at low signal-to-noise ratio (SNR) regimes are highlighted. The major contributions of this thesis are further elaborated below. …”
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Effects of Tip Clearance and Surface Roughness on Small-Scale Turbopump Impeller Performance by Ruecker, Kinjal A. L.

“…This lowers the effective tip clearance that separates the flow regimes. The contribution of blade tip leakage loss to total impeller loss decreases by up to 22% for surface roughness increased from an Rₐ value of 1 µm to 10 µm. …”
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Design and development of bio-medical devices using rapid prototyping techniques by Phua, Kenneth Khiang Song.

“…Many drug regimes must be carefully dosed as they are either too complicated to be self –administered or face low compliance by the patients themselves. …”
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The prevention and management of chronic kidney disease among patients with metabolic syndrome by Zhu, D, Judge, PK, Wanner, C, Haynes, R, Herrington, WG

“…In addition, statin-based regimens lower low-density lipoprotein cholesterol and reduce the risk of atherosclerotic disease (with no clinically meaningful effect on kidney outcomes). …”

Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. …”