Genomic profiling of mycobacterium tuberculosis strains, Myanmar by Aung, Htin Lin, Nyunt, Wint Wint, Fong, Yang, Biggs, Patrick J., Winkworth, Richard C., Lockhart, Peter J., Yeo, Tsin Wen, Hill, Philip C., Cook, Gregory M., Aung, Si Thu

“…Introducing new oral drugs to replace those currently used in treatment regimens for multidrug-resistant TB will also be useful for treating TB in Myanmar.…”
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Behind every domain there is a shift: adapting distortion-aware vision transformers for panoramic semantic segmentation by Zhang, J, Yang, K, Shi, H, ReiB, S, Peng, K, Ma, C, Fu, H, Torr, PHS, Wang, K, Stiefelhagen, R

“…Extensive experiments are conducted, which cover indoor and outdoor scenarios, and each of them is investigated with Pin2Pan and Syn2Real regimens. Trans4PASS+ achieves state-of-the-art performances on four domain adaptive panoramic semantic segmentation benchmarks. …”

Knowledge and practice regarding medication use among elderly with chronic diseases in Felda Tembangau 2, Kemayan, Pahang by Farid, Aina Natasha Mohd

“…The elderly population, defined as those aged 60 and above, faces unique challenges in managing chronic diseases due to physiological changes, limited access to healthcare information, and barriers in understanding and adhering to medication regimens. The aim of this study was to determine the levels of knowledge and practice regarding medication use among elderly with chronic diseases in FELDA Tembangau 2, Kemayan, Pahang and to explore the correlation between these two variables. …”
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The prevention and management of chronic kidney disease among patients with metabolic syndrome by Zhu, D, Judge, PK, Wanner, C, Haynes, R, Herrington, WG

“…In addition, statin-based regimens lower low-density lipoprotein cholesterol and reduce the risk of atherosclerotic disease (with no clinically meaningful effect on kidney outcomes). …”

Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. …”

Psychosocial predictors of self-reported medical adherence in patients with heart failure over 6 months : an examination of the influences of depression, self-efficacy, social supp... by Shen, Biing-Jiun, Maeda, Uta

“…Background Poor adherence to medical regimens is a serious problem that interferes with heart failure (HF) patients’ disease management and contributes to poor clinical outcomes. …”
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Clostridium difficile bacteriophage finding under normal and iron-limited conditions for the isolation of potential siderophore receptor-specific phages by Lim, Edsel Yong Xun

“…Phage therapy, known for its specificity of action, has emerged as a promising candidate for combating CDI, offering the potential to circumvent gut microbiome dysbiosis associated with conventional antibiotic regimens. However, research on Clostridium difficile (C. difficile) phage hunting has been relatively limited. …”
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The role of SPRTN protease in colorectal cancer chemotherapy by Peron, C

“…The first-line treatment of metastatic colorectal cancer (mCRC) is frequently based on combination chemotherapeutic regimens, where 5-fluorouracil is either associated with irinotecan (FOLFIRI) or oxaliplatin (FOLFOX). …”

Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction by Chen, Xinsong, Sifakis, Emmanouil G., Robertson, Stephanie, Neo, Shi Yong, Jun, Seong-Hwan, Tong, Le, Tay, Apple Hui Min, Lövrot, John, Hellgren, Roxanna, Margolin, Sara, Bergh, Jonas, Foukakis, Theodoros, Lagergren, Jens, Lundqvist, Andreas, Ma, Ran, Hartman, Johan

“…The accuracy was further supported by the correlation between WTC-based test results and patients' clinical responses in a separate validation study, where the neoadjuvant treatment regimens of 15 BC patients were mimicked. Collectively, the WTC model allows us to accomplish personalized drug testing within 10 d, even for small-sized tumors, highlighting its potential for individualized BC therapy. …”
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Hepatic effects of prolonged oral administration of Aqueous extracts from Trigonella foenum-graecum (Fenugreek) seeds explored through pathology techniques by Okorie, Nnaemeka, Ibe, Onyekachi Ewa, Okekpa, Simon Imakwu, Nwakpa, Anthony Chukwudi, Agom, Dansy Daniel, Pauline, Iyke-Ogbo, Adaeze, Obi Laura, Mmesomachi, Uche Bethel, Nyirahafashimana, Valentine, Obi, Ihuoma A.

“…Materials and methods: Thirty-five Norvegicus rattus weighing 150-200g were randomly assigned to five groups, with each subjected to distinct dietary regimens containing 2%, 4%, 6%, and 8% Trigonella foenum-graecum, and a control group. …”
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Antiretroviral therapy optimisation without genotype resistance testing : a perspective on treatment history based models by Prosperi, Mattia C. F., Sloot, Peter M. A., van de Vijver, David A. M. C., Rosen-Zvi, Michal, Altmann, André, Zazzi, Maurizio, Schülter, Eugen, Struck, Daniel, Di Giambenedetto, Simona, Kaiser, Rolf, Vandamme, Anne-Mieke, Sönnerborg, Anders

“…Sensitivity analyses, carried out on a data subset that included antiretroviral regimens commonly used in low to middle income countries, confirmed our findings. …”
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An observational study of the prevalence of metabolic syndrome in treatment-experienced people living with HIV in Singapore by Ang, Li Wei, Ng, Oon Tek, Boudville, Irving Charles, Leo, Yee Sin, Wong, Chen Seong

“…Background: While the use of combination antiretroviral therapy (cART) has conferred significant reduction in morbidity and mortality, there are growing concerns about the metabolic complications of antiretroviral regimens in HIV-infected patients. The aim of this study was to estimate the prevalence of metabolic syndrome (MetS) among people living with HIV (PLHIV) in Singapore. …”
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The dietetic practice of prescribing amino acid-based formulas in paediatrics patients without cow’s milk allergy: a single centre retrospective study by O’Connor, Graeme, Mansell, Melissa

“…Data were collected on demographics, anthropometrics, feed regimens, gastrointestinal symptoms, proton pump inhibitor use and serum phosphate concentration Results: 203 children were prescribed an AAF during the data collection period, of these, 154 of 203 (76%) patients had no allergies. …”
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