Determining targets for antiretroviral drug concentrations: a causal framework illustrated with pediatric efavirenz data from the CHAPAS-3 trial by Schomaker, M, Denti, P, Bienczak, A, Burger, D, Díaz, I, Gibb, DM, Walker, AS, McIlleron, H

“…<p><strong>Background:&nbsp;</strong>Determining a therapeutic window for maintaining antiretroviral drug concentrations within an appropriate range is required for identifying effective dosing regimens. The limits of this window are typically calculated using predictive models. …”

EU competition law : a roadmap for ASEAN? by Valockova, Barbora

“…The European Union’s competition policy and legal regime is instrumental in the functioning of the single market in the EU. …”
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Maximizing the performance of badminton athletes through core strength training: Unlocking their full potential using machine learning (ML) modeling by Ma, Shuzhen, Geok Soh, Kim, Japar, Salimah, Xu, Simao, Zhicheng, Guo

“…Incorporating core strength training into regular regimens can improve athletes' overall strength, endurance, balance, control, and prevent injuries. …”
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Shedding Light on Chemoresistance: The Perspective of Photodynamic Therapy in Cancer Management by Viana Cabral, Fernanda, Quilez Alburquerque, Jose, Roberts, Harrison James, Hasan, Tayyaba

“…Photodynamic therapy (PDT) has emerged as a promising photochemistry-based approach to address chemoresistance in cancer regimens. PDT not only induces cell death but also primes surviving cells, enhancing their susceptibility to subsequent therapies. …”
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Treatment options to support the elimination of Hepatitis C: an open label, factorial randomised controlled trial by Cooke, G, Le Manh, H, Flower, B, McCabe, L, Vu Thu Kim, H, Vo Thi, T, Dang Trong, T, Nguyen Thanh, D, Le Thanh, P, Dao Bach, K, Nguyen Thi Chau, A, Pham Ngoc, T, Vu Thu Thu, H, Dang Thi, B, Nguyen Kim, T, Ansari, A, Le Ngoc, C, Vo Minh, Q, Nguyen Thi Ngoc, P, Le Thi, T, Nguyen Bao, T, Kestelyn, E, Kingsley, C, Van Doorn, R, Rahman, M, Pett, S, Thwaites, G, Barnes, E, Day, J, Nguyen Van Vinh, C, Walker, AS

“…No randomised trials have compared these regimens and high cure rates may be achievable with shorter durations of therapy.…”

Dynamical blockade in a single-mode bosonic system by Ghosh, Sanjib, Liew, Timothy Chi Hin

“…We find that the underlying mechanism for the blockade is general, enhancing antibunching in the strongly nonlinear regime and inducing it in the weakly nonlinear regime, without fine-tuning the system parameters. …”
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Maxwell-type models for the effective thermal conductivity of a porous material with radiative transfer in the voids by Kiradjiev, KB, Halvorsen, SA, Van Gorder, RA, Howison, SD

“…In the high-temperature regime, radiative transfer within voids strongly influences the thermal conductivity of the bulk material. …”

Drug interaction between acetyltanshinone IIA and rapamycin in breast cancer cells by Wong, De Pin

“…Developing in vitro drug combination study is essential for the development of new and effective combination regimens. In this project, the objective is to investigate the synergistic potential between two anti breast cancer agent, rapamycin and acetyltanshinone IIA (ATA) in breast cancer cells. …”
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Enhancing quantum synchronization through homodyne measurement, noise, and squeezing by Shen, Yuan, Soh, Hong Yi, Fan, Weijun, Kwek, Leong Chuan

“…Homodyne measurement emerges as one of the successful candidates for this task but preferably in the semiclassical regime. In our work, we focus on the phase synchronization of a harmonic-driven quantum Stuart-Landau oscillator and show that the enhancement induced by homodyne measurement persists into the quantum regime. …”
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Topological effects on the magnetoconductivity in topological insulators by Sacksteder, Vincent E., Arnardottir, Kristin Bjorg, Kettemann, Stefan, Shelykh, Ivan A.

“…In this wrapped regime the magnetoconductivity's dependence on temperature, typically 1/T2 in 2-DEGs, disappears. …”
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Stress evolution of GaN/AlN heterostructure grown on 6H-SiC substrate by plasma assisted molecular beam epitaxy by Agrawal, Manvi, Ravikiran, Lingaparthi, Dharmarasu, Nethaji, Radhakrishnan, K., Karthikeyan, Giri Sadasivam, Zheng, Yuanjin

“…GaN/AlN structure is found to form buried cracks when AlN is grown in the intermediate growth regime(III/V∼1)and GaN is grown under N-rich growth regime (III/V<1). …”
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Myanmar in Eu-Asean relations by Magnus Petersson

“…A rather skeptical view is emphasized on the ‘ASEAN Way’ in dealing with the military regime, and for the overall political dialogue with the European Union.…”
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In Vivo RNA Delivery to Hematopoietic Stem and Progenitor Cells via Targeted Lipid Nanoparticles by Shi, Dennis, Toyonaga, Sho, Anderson, Daniel G

“…However, these therapies have several limitations owing to the manufacturing complexities and toxicity resulting from required conditioning regimens. Here, we developed a c-kit (CD117) antibody-targeted lipid nanoparticle (LNP) that, following a single intravenous injection, can deliver RNA (both siRNA and mRNA) to HSCs in vivo in rodents. …”
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Disposition kinetics of tylosin administered intravenously and intramuscularly in Desert Sheep and Nubian Goats by Taha, A.A., Elsheikh, H.A., Khalafalla, A.E., Osman, I. A. M., Abdullah, A. Salam

“…The present study has shown that, despite the significant differences in some of the drug pharmacokinetic parameters between sheep and goats for the i.v. route, identical intravenous and intramuscular dosage regimens of tylosin may be recommended for the two species.…”
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Targeted hematopoietic stem cell depletion through SCF-blockade by Chan, Yan Y., Ho, Pui Y., Dib, Carla, Swartzrock, Leah, Rayburn, Maire, Willner, Hana, Ko, Ethan, Ho, Katie, Down, Julian D., Wilkinson, Adam C., Nakauchi, Hiro, Denis, Morgane, Cool, Taylor, Czechowicz, Agnieszka

“…Further, to augment efficacy, combination regimens were also explored. Results We confirm that only ACK2 inhibits SCF binding fully and prevents HSC proliferation in vitro. …”
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A review of offshore decommissioning regulations in five countries – strengths and weaknesses by Fam, Mei Ling, Konovessis, Dimitris, Tan, Hoon Kiang, Ong, Lin Seng

“…Major differences lie in two overarching philosophies of the framework - a prescriptive regime versus a goal-setting regime. Other decommissioning aspects appear to attract increasing attention, such as in expanding clarity on in situ decommissioning, residual liabilities, optimising finance related issues of decommissioning and offshore to onshore waste movement. …”
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中国民间故事的文化思考 ：以巧媳妇故事类型为例 = Cultural considerations in Chinese folktales : a case study of the Qiao Xi Fu story type by 蓝智欣 Lam, Zhi Xin

“…Being regarded lowly in the patriarchal clan system, women were obligated to conform to regimented rules and standards, on top of tending to family elders and fulfilling household duties. …”
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Better understanding of the social services sector in Singapore. by Loh, Candice Jiahui., Phoon, Sharon Yien Mei., Thung, Sim Yee.

“…Make recommendations to improve current regulatory regime.…”
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Multiple scattering of light in cold atomic clouds in a magnetic field by Sigwarth, Olivier, Labeyrie, Guillaume, Delande, Dominique, Miniatura, Christian

“…We then consider the multiple-scattering regime and address the fate of the coherent-backscattering (CBS) effect. …”
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Designing novel multilayered nanocomposites for high-performance coating materials with online strain monitoring capability by Anwar Ali, Hashina Parveen, Radchenko, Ihor, Zhou, Jiahui, Qing, Liu, Budiman, Arief

“…These materials can withstand very high strains in the elastic regime without any inelastic relaxation due to plasticity or fracture compared to its bulk counterparts. …”
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