Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma by Xiong, Sinan, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Tan, Tuan Zea, Toh, Sabrina Hui-Min, Tang, Nicole Xin Ning, Jia, Yunlu, See, Yi Xiang, Fullwood, Melissa Jane, Sanda, Takaomi, Chng, Wee-Joo

“…It remains poorly understood how chromatin rewiring of regulatory elements contributes to tumorigenesis and therapy resistance in myeloma. …”
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The Expansion of Incentive (Performance-Based) Regulation of Electricity Distribution and Transmission in the United States by Joskow, Paul L.

“…I examine developments in the application of performance-based regulation (PBR) to electricity distribution and transmission in the United States. …”
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Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells by Sin, Wei Xiang

“…Our data identified a tonic IL-27p28-IFN-β signaling axis as a novel cell type-specific regulator of TLR4-mediated IFN-β induction through the regulation of constitutively expressed IRF7.…”
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Towards understanding genome regulation via high-resolution analysis of chromatin accessibility by Dai, L

“…<p>Next generation sequencing has been used to in functional genomics to rep- resent specific aspects of chromatin structure, DNA-protein interactions and the epigenome, enriching the knowledge of the non-coding genome which plays significantly roles in gene regulation but is vaguely understood. Among the assays for functional genomics, Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a powerful and popular tool as its simple read out of ‘chromatin accessibility’ provides both the positioning of functional regulatory elements and a general representation of the active genome. …”

Commercialization strategy for FormaCyte therapeutics: Type 1 diabetes patient insights and regulatory pathway analysis on US FDA's impact on other jurisdictions by Liu, Fanzheng

“…However, limited access to real-life experiences of T1D patients and challenges in patient engagement underscore the necessity for innovative outreach methods and focused interviews to enhance patient-centric development, crucial for development success and regulatory strategy. Additionally, existing regulatory literature primarily focuses on regenerative medicine, not specifically CT, and lacks comprehensive insights into the impact of US regulations on other jurisdictions, highlighting the need for a more inclusive review to inform FormaCyte's tailored regulatory approach across diverse jurisdictions. 25 patients are interviewed in this project, and insights on their glucose management method, major pain points, lifestyle and mindset, expenditure, and thoughts on FormaCyte are gathered. …”
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Electricity sector deregulation and consumer protection: assessing the imperatives of a competition: Assessing the imperatives of a competition law and competition regulatory authority in Nigeria by Usman, Dahiru Jafaru, Yaacob, Nurli, A. Rahman, Aspalella

“…Literature abounds on the high risk of the electricity sector deregulation and the susceptibility of the deregulated electricity markets to manipulations and abuse by the electricity service providers.For better and fair market operations and the protection of consumers’ interest, the paper adopts the doctrinal research approach and assesses the imperatives of competition law and competition structures in the deregulated Nigerian electricity market.The paper found that the Nigerian experiment took off without the necessary consumer protection structures such as a competition law and competition regulatory agency leaving the electricity consumers at the mercy of the electricity service providers.The paper concludes that the country urgently needs a comprehensive competition regime to guarantee consumer benefits and to prevent substituting public monopoly with a private monopoly in the new Nigerian electricity market.…”
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A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling by Deng, H, Zhang, J, Wang, Y, Joshi, D, Pi, X, De Val, S, Schwartz, MA

“…Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. In mice, surgically induced high FSS elevated BMPER expression, inactivated Smad1/5 and induced vessel outward remodeling. …”

Regulation of Adenine Nucleotide Concentration at Endothelium-Fluid Interface by Viscous Shear Flow by Shen, Jian, Gimbrone, Michael A. Jr., Luscinskas, Francis W., Dewey, C. Forbes Jr.

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MMP14 in sarcoma : a regulator of tumor microenvironment communication in connective tissues by Gonzalez-Molina, Jordi, Gramolelli, Silvia, Liao, Zehuan, Carlson, Joseph W., Ojala, Päivi M., Lehti, Kaisa

“…This regulation mediates processes such as ECM degradation and remodeling, cell invasion, and cancer metastasis. …”
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Membranes with ZIF-8 regulated MXene nanosheet stacks for efficient molecular sieving by Li, Jian, Li, Lei, Li, Xin, Dong, Liangliang, Wang, Zhenyu, Shen, Jiangnan, Van der Bruggen, Bart

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PSO-based model predictive control for load frequency regulation with wind turbines by Fan, Wei, Hu, Zhijian, Veerasamy, Veerapandiyan

“…The classical MPC model was modified to incorporate the particle swarm optimization algorithm for the power generation model to regulate the system frequency. In addition to addressing the unpredictability of wind turbine generation, the presented PSO-MPC strategy not only addresses the randomness of wind turbine generation, but also reduces the computation burden of traditional MPC. …”
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Design of a low dropout voltage regulator (ldo) for wireless sensor nodes by Lee, Hong Ze

“…A low dropout voltage regulator for wireless sensor nodes is proposed such that it provides a fixed output voltage of 0.6V irrespective of the load under a supply voltage of 0.9V. …”
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Coordinated Control of Distributed Energy-Storage Systems for Voltage Regulation in Distribution Networks by Wang, Yu, Tan, K. T., Peng, Xiao Yang, So, Ping Lam

“…The distributed control using the consensus algorithm regulates the feeder voltages within the required limits, while the localized control regulates the state of charge (SoC) of each ESS within the desired SoC range. …”
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Different modes of regulation govern miRNA expression levels in Drosophila melanogaster by Lim, Mandy Yu Theng

“…Post-transcriptional mechanisms that regulate miRNA expression during fly embryogenesis are not well understood. …”
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Heterogeneity within colorectal cancer cell lines and epigenetic regulation of CD24 by Ibn Ayub, M

“…This thesis investigated the role of methylation in dynamic regulation of CD24 based heterogeneity in colorectal cancer cell lines. …”

Investigating the role of lysine demethylase UTX-1 in lifespan regulation of C. elegans by Guillermo, A

“…<p>That ageing can be epigenetically regulated has garnered considerable interest due to the implication that ageing is incredibly plastic and therefore, potentially reversible. …”

The role of executive function in cognitive reappraisal: a meta-analytic review by Toh, Wei Xing, Keh, Jun Sheng, Gross, James J., Carstensen, Laura L.

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Messenger and message: uncovering the roles, rhythm and regulation of extracellular vesicles in plant biotic interactions by Qiao, SA, Roth, R

“…Here, we review recent research exploring the roles of these EVs, both plant and microbial, highlighting emerging trends of functional conservation between species and across kingdoms, complemented by the heterogeneity of EV subpopulations at the organism level that places EVs as powerful regulatory mechanisms in plant biotic interactions.…”

Treating the symptoms or the disease? Analysing the UK Online Safety Act's approach to digital regulation by Nash, V, Felton, L

“…In recent years, the pace of Internet regulation around the world has quickened, with states increasingly confident that they can and should hold major platform companies to account. …”

Unraveling heterogeneity in transcriptome and its regulation through single-cell multi-omics technologies by Xing, Qiao Rui, Cipta, Nadia Omega, Hamashima, Kiyofumi, Liou, Yih-Cherng, Koh, Cheng-Gee, Loh, Yuin-Han

“…Integrative analysis of multi-omics datasets unravels the relationships between cellular modalities, builds sophisticated regulatory networks, and provides a holistic view of the cell state. …”
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