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Enhancing E. coli tolerance towards oxidative stress via engineering its global regulator cAMP Receptor Protein (CRP)
Published 2013“…Here, we aim to improve E. coli performance under oxidative stress via engineering its global regulator cAMP receptor protein (CRP), which can directly or indirectly regulate redox-sensing regulators SoxR and OxyR, and other ~400 genes in E. coli. …”
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Journal Article -
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Relationships among emotion regulation, depression, anxiety, stress, and physical health-related quality of life in coronary heart disease patients
Published 2020“…Coronary heart disease (CHD) is the third leading cause of death in Singapore. Although emotion regulation is a significant determinant of CHD patient’s quality of life, not many studies have assessed the impact of change in emotion regulation on physical functioning over time. …”
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Final Year Project (FYP) -
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A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling
Published 2024“…Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. In mice, surgically induced high FSS elevated BMPER expression, inactivated Smad1/5 and induced vessel outward remodeling. …”
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Voltage and frequency stability enhancement with an automatic voltage regulator and power system stabilizer in a ring-structured power system post generator loss
Published 2025“…This study analyses the transient stability of the IEEE 9-bus test system in the context of generator loss and delayed circuit breaker response, emphasizing the impact of Automatic Voltage Regulator (AVR) and Power System Stabilizer (PSS) on damping reduction and transient recovery time. …”
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Congenital myasthenic syndromes: characterisation of a new animal model, exploring potential novel therapies and assessing the outcome of COVID-19 infection
Published 2024Subjects: “…Allosteric regulation…”
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Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells
Published 2018“…Here, we report that HIF-2α up-regulates the expression of CD70, a cancer-related surface antigen that improves anchorage-independent growth in cancer cells and is associated with poor clinical prognosis, which can be induced via epigenetic modifications mediated by DNMT1. …”
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Dance battle: power relations within the Singapore dance scene
Published 2024Subjects: Get full text
Final Year Project (FYP) -
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Learning from the community: iterative co-production of a programme to support the development of attention, regulation and thinking skills in toddlers at elevated likelihood of autism or ADHD
Published 2025“…The logic model for the resultant programme—Supporting Toddlers with a connection to autism or ADHD to develop strong Attention, Regulation and Thinking skills (START)—involves three mechanisms of change: The child has appropriate play-based opportunities to practise EF skills; Parenting behaviours linked to strong EFs are encouraged; Parents are empowered to improve environmental-fit for their child so that EF stressors are reduced.…”
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Emerging functions of alternative splicing coupled with nonsense-mediated decay
Published 2015Subjects: “…Post-transcriptional regulation of gene expression…”
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Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated siRNA gene silencing
Published 2013“…In this study, we investigated the efficacy of siRNA–poly(caprolactone-co-ethylethylene phosphate) nanofibers in controlling fibrous capsule formation through the down-regulation of collagen type I (COL1A1) in vitro and in vivo. …”
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Essays in comparative political economy: bureaucracy and participation in policymaking
Published 2021Subjects:Thesis -
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16.323 Principles of Optimal Control, Spring 2006
Published 2006Subjects: Get full text
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