Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells by Sin, Wei Xiang

“…The transcription factor IRF7 is thought to be primarily involved in the regulation of type I IFN responses in viral infections. …”
Get full text

Mef2c regulates the morphology and synapse formation of cerebellar Purkinje cells by Poon, Dennis Jun Jie

Get full text

Coordinated Control of Distributed Energy-Storage Systems for Voltage Regulation in Distribution Networks by Wang, Yu, Tan, K. T., Peng, Xiao Yang, So, Ping Lam

“…The distributed control using the consensus algorithm regulates the feeder voltages within the required limits, while the localized control regulates the state of charge (SoC) of each ESS within the desired SoC range. …”
Get full text
Get full text

Different modes of regulation govern miRNA expression levels in Drosophila melanogaster by Lim, Mandy Yu Theng

“…MiRNAs are a class of small non-coding RNAs that play important roles in post-transcriptional regulation of complementary target mRNAs. Loquacious (Loqs) is a dsRNA-binding protein that binds Dicer-1 to cleave pre-miRNAs into short duplexes. …”
Get full text
Get full text

Heterogeneity within colorectal cancer cell lines and epigenetic regulation of CD24 by Ibn Ayub, M

“…This thesis investigated the role of methylation in dynamic regulation of CD24 based heterogeneity in colorectal cancer cell lines. …”

Investigating the role of lysine demethylase UTX-1 in lifespan regulation of C. elegans by Guillermo, A

“…<p>That ageing can be epigenetically regulated has garnered considerable interest due to the implication that ageing is incredibly plastic and therefore, potentially reversible. …”

Towards understanding genome regulation via high-resolution analysis of chromatin accessibility by Dai, L

“…<p>Next generation sequencing has been used to in functional genomics to rep- resent specific aspects of chromatin structure, DNA-protein interactions and the epigenome, enriching the knowledge of the non-coding genome which plays significantly roles in gene regulation but is vaguely understood. Among the assays for functional genomics, Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a powerful and popular tool as its simple read out of ‘chromatin accessibility’ provides both the positioning of functional regulatory elements and a general representation of the active genome. …”

Design of a 40nm CMOS Internet-of-Things regulator with fast power on and off by Zhong, Si Yuan

“…Low Dropout (LDO) regulator is an important building block for Internet of Things (IoT) and System-on-Chip (SoC). …”
Get full text

Design of a fast response CMOS low dropout regulator for system-on-chip applications by Wang, Haoran

“…The Low-DropOut (LDO) regulator is regarded as one of the important building blocks in power management. …”
Get full text

Cyclin-Dependent Kinase-Dependent Phosphorylation of Sox2 at Serine 39 Regulates Neurogenesis by Lim, Shuhui, Bhinge, Akshay, Bragado Alonso, Sara, Aksoy, Irene, Aprea, Julieta, Cheok, Chit Fang, Calegari, Federico, Stanton, Lawrence W., Kaldis, Philipp

Subjects: Get full text
Get full text

Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling by Martin Perez, E

“…Hence, hepatic insulin action provides an important layer of regulation in the maintenance of whole-body metabolic homeostasis, and its dysregulation is closely associated with metabolic disease progression. …”

Sympathetic-neuron-derived neuropeptide Y (NPY) regulates adipose tissue immunometabolic homeostasis by Zhu, Y

“…These cKO mice have whitened BAT with reduced thermogenic ability and lower energy expenditure even before the onset of obesity; they develop adult-onset obesity on a regular chow diet and are more susceptible to diet-induced obesity without increasing food consumption. …”

Understanding collective regularity in human mobility as a familiar stranger phenomenon by Leng, Yan, Santistevan, Dominiquo, Pentland, Alex

“…Using countrywide mobile phone records from Andorra, we empirically show the existence of such a phenomenon as well as details concerning these strangers’ relative social relations. To understand the social and spatial components of familiar strangers more deeply, we study the temporal regularity and spatial structure of collective urban mobility to shed light on the mechanisms that guide these interactions. …”
Get full text

Treating the symptoms or the disease? Analysing the UK Online Safety Act's approach to digital regulation by Nash, V, Felton, L

“…Against this backdrop we assess the UK's Online Safety Act 2023 (OSA), which was expected to provide an innovative and broad-reaching ‘systems-based’ approach to reducing user risks and harms, particularly in relation to child safety. We argue that although the Act does incorporate measures to regulate platform design, it fails to fully embrace this and faces some challenges in ensuring proportionality and accountability. …”

Natural variations in grain length 10 (GL10) regulate rice grain size by Zhan, P, Ma, S, Xiao, Z, Li, F, Wei, X, Lin, S, Wang, X, Ji, Z, Fu, Y, Pan, J, Zhou, M, Liu, Y, Chang, Z, Li, L, Bu, S, Liu, Z, Zhu, H, Liu, G, Zhang, G, Wang, S

“…Additionally, GL10 participates in the regulation of gibberellic acid (GA) signaling pathway genes in young panicle tissues. …”

A model for cis-regulation of transcriptional condensates and gene expression by proximal lncRNAs by Natarajan, Pradeep, Shrinivas, Krishna, Chakraborty, Arup K

“…Long noncoding RNAs (lncRNAs) perform several important functions in cells including cis-regulation of transcription. Barring a few specific cases, the mechanisms underlying transcriptional regulation by lncRNAs remain poorly understood. …”
Get full text

Regulation of lipid droplets in live preadipocytes using optical diffraction tomography and Raman spectroscopy by Hsieh, Chao-Mao, Liu, Patricia Yang, Chin, Lip Ket, Zhang, Jing Bo, Wang, Kuan, Sung, Kung-Bin, Ser, Wee, Bourouina, Tarik, Leprince-Wang, Yamin, Liu, Ai-Qun

“…However, it remains challenging to study the regulation of lipid droplets in live preadipocytes using conventional microscopic techniques. …”
Get full text

Study on the regulation of focal adesions and cortical actin by matrix nanotopography in 3D environment by Han, Jingjing, Lin, Keng-Hui, Chew, Lock Yue

“…Matrix nanotopography plays an important role in regulating cell behaviors by providing spatial as well as mechanical cues for cells to sense. …”
Get full text

Unraveling heterogeneity in transcriptome and its regulation through single-cell multi-omics technologies by Xing, Qiao Rui, Cipta, Nadia Omega, Hamashima, Kiyofumi, Liou, Yih-Cherng, Koh, Cheng-Gee, Loh, Yuin-Han

Get full text

Involuntary transnationalism and regulated precarity: lived experiences of skilled Chinese and Indian migrants in Singapore by Zhan, Shaohua, Zhou, Min

“…Based on analysis of survey data and in-depth interviews of skilled Chinese and Indian migrants in Singapore, we find that skilled foreign migrants face employment insecurity and other vulnerabilities largely due to visa regulations and that they have to turn to transnationalism as a coping strategy to mitigate precarity and temporality.…”
Get full text