Guiding transition metal-doped hollow cerium tandem nanozymes with elaborately regulated multi-enzymatic activities for intensive chemodynamic therapy by Dong, Shuming, Dong, Yushan, Liu, Bin, Liu, Jing, Liu, Shikai, Zhao, Zhiyu, Li, Wenting, Tian, Boshi, Zhao, Ruoxi, He, Fei, Gai, Shili, Xie, Ying, Yang, Piaoping, Zhao, Yanli

“…This work presents a powerful paradigm to achieve intensive NCDT efficacy by simultaneously regulating multi-enzymatic activities of Ce-based nanozymes and perturbing the H2O2 homeostasis in tumor microenvironment.…”
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Super enhancer acquisition drives expression of oncogenic PPP1R15B that regulates protein homeostasis in multiple myeloma by Xiong, Sinan, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Tan, Tuan Zea, Toh, Sabrina Hui-Min, Tang, Nicole Xin Ning, Jia, Yunlu, See, Yi Xiang, Fullwood, Melissa Jane, Sanda, Takaomi, Chng, Wee-Joo

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A KLF2-BMPER-Smad1/5 checkpoint regulates high fluid shear stress-mediated artery remodeling by Deng, H, Zhang, J, Wang, Y, Joshi, D, Pi, X, De Val, S, Schwartz, MA

“…Here we report that high FSS suppresses Smad1/5 by elevating KLF2, which induces the bone morphogenetic protein (BMP) pathway inhibitor, BMP-binding endothelial regulator (BMPER), thereby de-inhibiting Akt. In mice, surgically induced high FSS elevated BMPER expression, inactivated Smad1/5 and induced vessel outward remodeling. …”

Voltage and frequency stability enhancement with an automatic voltage regulator and power system stabilizer in a ring-structured power system post generator loss by Zetty Adibah, Kamaruzzaman, Nur Zahirah, Mohd Ali, Ahmad Syahiman, Mohd Shah

“…This study analyses the transient stability of the IEEE 9-bus test system in the context of generator loss and delayed circuit breaker response, emphasizing the impact of Automatic Voltage Regulator (AVR) and Power System Stabilizer (PSS) on damping reduction and transient recovery time. …”
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A rapid CRISPR competitive assay for in vitro and in vivo discovery of potential drug targets affecting the hematopoietic system by Shen, Yunbing, Jiang, Long, Iyer, Vaishnavi Srinivasan, Raposo, Bruno, Dubnovitsky, Anatoly, Boddul, Sanjaykumar V., Kasza, Zsolt, Wermeling, Fredrik

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Congenital myasthenic syndromes: characterisation of a new animal model, exploring potential novel therapies and assessing the outcome of COVID-19 infection by Alabaf, S

Subjects: “…Allosteric regulation…”

The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

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Identification of potential common cyclic-di-GMP regulated biomarkers among three gram negative bacteria via transcriptomic and metabolomic profiling by Cai, Zhao

“…In most Gram-negative bacteria, biofilm formation can be regulated by a secondary messenger, bis-(3'-5')-cyclic dimeric guanosine monophos-phate, c-di-GMP. …”
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The Tudor domain protein Tapas, a homolog of the vertebrate Tdrd7, functions in the piRNA pathway to regulate retrotransposons in germline of Drosophila melanogaster by Patil, Veena S., Anand, Amit, Chakrabarti, Alisha, Kai, Toshie

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Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells by Kitajima, Shojiro, Lee, Kian Leong, Fujioka, Masaki, Sun, Wendi, You, Jia, Chia, Grace Sushin, Wanibuchi, Hideki, Tomita, Shuhei, Araki, Marito, Kato, Hiroyuki, Poellinger, Lorenz

“…Here, we report that HIF-2α up-regulates the expression of CD70, a cancer-related surface antigen that improves anchorage-independent growth in cancer cells and is associated with poor clinical prognosis, which can be induced via epigenetic modifications mediated by DNMT1. …”
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Dance battle: power relations within the Singapore dance scene by Te, Hui Ley, Tjong, Vanessa Gabriela

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Learning from the community: iterative co-production of a programme to support the development of attention, regulation and thinking skills in toddlers at elevated likelihood of autism or ADHD by Hendry, A, Hulks, V, Murphy, S, Radford, H, Smith, S, Charman, T, Mathers, S, Rhodes, S, Scerif, G

“…The logic model for the resultant programme—Supporting Toddlers with a connection to autism or ADHD to develop strong Attention, Regulation and Thinking skills (START)—involves three mechanisms of change: The child has appropriate play-based opportunities to practise EF skills; Parenting behaviours linked to strong EFs are encouraged; Parents are empowered to improve environmental-fit for their child so that EF stressors are reduced.…”

Emerging functions of alternative splicing coupled with nonsense-mediated decay by Hamid, Fursham M., Makeyev, Eugene V.

Subjects: “…Post-transcriptional regulation of gene expression…”
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Increasing international students’ autonomy and boosting their engagement via the use of active self-correction in writing: a transformative approach to sustainable self-regulated learning in business schools by Meletiadou, Eleni

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Plasmacytoid dendritic cells are central regulators of the humoral ChAdOx1 nCoV-19 vaccine response in a human tonsil organoid model by Provine, N, Pudjohartono, M, Powell, K, Ferry, H, Barnes, E, Klenerman, P

Controlling fibrous capsule formation through long-term down-regulation of collagen type I (COL1A1) expression by nanofiber-mediated siRNA gene silencing by Rujitanaroj, Pim-On, Jao, Brian, Yang, Junghoon, Wang, Feng, Anderson, James M., Wang, Jun, Chew, Sing Yian

“…In this study, we investigated the efficacy of siRNA–poly(caprolactone-co-ethylethylene phosphate) nanofibers in controlling fibrous capsule formation through the down-regulation of collagen type I (COL1A1) in vitro and in vivo. …”
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Challenges of navigating the Rome I Regulation in respect of the Rome Convention, Brexit, and Consumer Protection — Comments on CJEU, judgment of 14.9.2023 – C‑632/21 – Diamond Resorts Europe by Ungerer, J

Essays in comparative political economy: bureaucracy and participation in policymaking by Taras, J

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PE.210 SCUBA, Fall 2006 by Taylor, Halston W.

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16.323 Principles of Optimal Control, Spring 2006 by How, Jonathan P.

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