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21
Regulation and function of innate-like T cells
Published 2021“…CD161-expressing T-cell subsets share a transcriptional and functional phenotype, including the ability to be activated by cytokines in a T-cell receptor-independent manner, similar to NK cells. The regulation and function of CD161-expressing cells as well as their role in cancer is not fully understood, however. …”
Thesis -
22
Design and build a positive linear regulator
Published 2018“…This final year project report will explain the background and functions of a linear regulator. Linear regulators are preferred for many applications as they require low cost and are of low complexity. …”
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Final Year Project (FYP) -
23
Design and build a negative linear regulator
Published 2018“…The report will go in depth on how the different components function in the regulator circuit and the working principle.…”
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Final Year Project (FYP) -
24
Activated invariant NKT cells regulate osteoclast development and function
Published 2011“…OC progenitor activity is positively regulated by TNF-α and negatively regulated by IFN-γ, but is IL-4 and IL-17 independent. …”
Journal article -
25
Key transcriptional regulators of neutrophil function in inflammation
Published 2021“…Of note, there is partial understanding of transcription factors (TFs) that act as key regulators to control neutrophil development and inflammatory responses. …”
Thesis -
26
Catalysis and regulation of cyclic dinucleotide specific phosphodiesterases
Published 2011“…The PAS domain of YybT was unexpectedly found to bind them and regulate the PDE activity in response to them or nitric oxide. …”
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Thesis -
27
Characterization of the translational regulation of BIM 3’ UTR
Published 2014“…BIM (BCL-2-interacting mediator of cell death) plays a central role in the regulation of the intrinsic apoptotic pathway by controlling the delicate balance between the induction of apoptosis and cell survival. …”
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Final Year Project (FYP) -
28
Unravelling gene regulation in the epidermis during differentiation
Published 2018“…Polyamine levels vary between tissues and are tightly regulated. They are differentially distributed throughout the epidermis and dermis of normal human skin with higher levels being found in the epidermis. …”
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Thesis-Doctor of Philosophy -
29
Design of a power regulator for solar energy application
Published 2014Get full text
Final Year Project (FYP) -
30
COVID-19 regulations, political Institutions, and the environment
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Journal Article -
31
Structure and regulation of the mycobacterial F1-ATPase
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Thesis-Doctor of Philosophy -
32
Roles of POPX2 phosphatase in the regulation of apoptosis
Published 2015“…TGF-β activated kinase 1 (TAK1) is a MAPK kinase kinase that has emerged as an important regulator in immune response, embryo development, tumorigenesis and cell death. …”
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Thesis -
33
The role of POPX2 in the regulation of hippo pathway
Published 2018“…The Hippo pathway has gained immense attention due to its key role in regulating organ size as well as its relevance to tissue regeneration and cancer. …”
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Thesis -
34
Regulation of Stress Responses and Translational Control by Coronavirus
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Journal Article -
35
Introduction. Post-Soviet censorship and regulation in Russia
Published 2024Get full text
Book Section -
36
Function and regulation of the ADP-ribosylhydrolase TARG1
Published 2024“…An additional research goal emerged from studying the synergistic function of TARG1 and PARG, namely revealing the molecular mechanisms that regulate the degradation of TARG1 upon PARG inhibition.…”
Thesis -
37
ZAP isoforms regulate unfolded protein response and epithelial- mesenchymal transition
Published 2023“…We showed that the ZAP isoforms regulated different UPR branches under resting and stress conditions and affected cell viability during ER stress. …”
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Journal Article -
38
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39
The Long Noncoding RNA RMST Interacts with SOX2 to Regulate Neurogenesis
Published 2016“…RMST expression is specific to the brain, regulated by the transcriptional repressor REST, and increases during neuronal differentiation, indicating a role in neurogenesis. …”
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Journal Article -
40
Regulation of coronavirus gene expression by the 5'-untranslated region.
Published 2010“…The regulatory properties of the 5’-untranslated region (5’-UTR) of the avian infectious bronchitis virus (IBV) were investigated through designing of plasmids which contained different mutations within the 5’-UTR: full-length (pUTR-wt), 362- nucleotides (nts) deleted (pUTR-362del) and stem-loop 1 (SL1) disrupted (pSL1- dsmut). …”
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Final Year Project (FYP)