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101
Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling
Published 2024“…Hence, hepatic insulin action provides an important layer of regulation in the maintenance of whole-body metabolic homeostasis, and its dysregulation is closely associated with metabolic disease progression. …”
Thesis -
102
The Expansion of Incentive (Performance-Based) Regulation of Electricity Distribution and Transmission in the United States
Published 2024“…I examine developments in the application of performance-based regulation (PBR) to electricity distribution and transmission in the United States. …”
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Article -
103
Transcriptional regulation of type I interferon responses of myeloid antigen presenting cells
Published 2016“…The transcription factor IRF7 is thought to be primarily involved in the regulation of type I IFN responses in viral infections. …”
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Thesis -
104
Towards understanding genome regulation via high-resolution analysis of chromatin accessibility
Published 2023“…<p>Next generation sequencing has been used to in functional genomics to rep- resent specific aspects of chromatin structure, DNA-protein interactions and the epigenome, enriching the knowledge of the non-coding genome which plays significantly roles in gene regulation but is vaguely understood. Among the assays for functional genomics, Assay for Transposase-Accessible Chromatin using sequencing (ATAC-seq) is a powerful and popular tool as its simple read out of ‘chromatin accessibility’ provides both the positioning of functional regulatory elements and a general representation of the active genome. …”
Thesis -
105
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106
MMP14 in sarcoma : a regulator of tumor microenvironment communication in connective tissues
Published 2020“…This regulation mediates processes such as ECM degradation and remodeling, cell invasion, and cancer metastasis. …”
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Journal Article -
107
Membranes with ZIF-8 regulated MXene nanosheet stacks for efficient molecular sieving
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Journal Article -
108
PSO-based model predictive control for load frequency regulation with wind turbines
Published 2023“…The classical MPC model was modified to incorporate the particle swarm optimization algorithm for the power generation model to regulate the system frequency. In addition to addressing the unpredictability of wind turbine generation, the presented PSO-MPC strategy not only addresses the randomness of wind turbine generation, but also reduces the computation burden of traditional MPC. …”
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Journal Article -
109
Mef2c regulates the morphology and synapse formation of cerebellar Purkinje cells
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Final Year Project (FYP) -
110
Design of a low dropout voltage regulator (ldo) for wireless sensor nodes
Published 2017“…A low dropout voltage regulator for wireless sensor nodes is proposed such that it provides a fixed output voltage of 0.6V irrespective of the load under a supply voltage of 0.9V. …”
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Final Year Project (FYP) -
111
Coordinated Control of Distributed Energy-Storage Systems for Voltage Regulation in Distribution Networks
Published 2016“…The distributed control using the consensus algorithm regulates the feeder voltages within the required limits, while the localized control regulates the state of charge (SoC) of each ESS within the desired SoC range. …”
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Journal Article -
112
Different modes of regulation govern miRNA expression levels in Drosophila melanogaster
Published 2019“…MiRNAs are a class of small non-coding RNAs that play important roles in post-transcriptional regulation of complementary target mRNAs. Loquacious (Loqs) is a dsRNA-binding protein that binds Dicer-1 to cleave pre-miRNAs into short duplexes. …”
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Thesis-Doctor of Philosophy -
113
Heterogeneity within colorectal cancer cell lines and epigenetic regulation of CD24
Published 2016“…This thesis investigated the role of methylation in dynamic regulation of CD24 based heterogeneity in colorectal cancer cell lines. …”
Thesis -
114
Investigating the role of lysine demethylase UTX-1 in lifespan regulation of C. elegans
Published 2018“…<p>That ageing can be epigenetically regulated has garnered considerable interest due to the implication that ageing is incredibly plastic and therefore, potentially reversible. …”
Thesis -
115
The role of executive function in cognitive reappraisal: a meta-analytic review
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Journal Article -
116
Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis
Published 2025“…We identified two epigenetic enzyme inhibitors as novel regulators of sprouting angiogenesis: A196, a selective SUV4-20H1/H2 inhibitor, demonstrated pro-angiogenic effects through increased H4K20me1 levels and upregulation of cell cycle associated genes, including MCM2 and CDK4. …”
Journal article -
117
Messenger and message: uncovering the roles, rhythm and regulation of extracellular vesicles in plant biotic interactions
Published 2024“…Here, we review recent research exploring the roles of these EVs, both plant and microbial, highlighting emerging trends of functional conservation between species and across kingdoms, complemented by the heterogeneity of EV subpopulations at the organism level that places EVs as powerful regulatory mechanisms in plant biotic interactions.…”
Journal article -
118
Treating the symptoms or the disease? Analysing the UK Online Safety Act's approach to digital regulation
Published 2024“…In recent years, the pace of Internet regulation around the world has quickened, with states increasingly confident that they can and should hold major platform companies to account. …”
Journal article -
119
Sympathetic-neuron-derived neuropeptide Y (NPY) regulates adipose tissue immunometabolic homeostasis
Published 2024“…These cKO mice have whitened BAT with reduced thermogenic ability and lower energy expenditure even before the onset of obesity; they develop adult-onset obesity on a regular chow diet and are more susceptible to diet-induced obesity without increasing food consumption. …”
Thesis -
120
Unraveling heterogeneity in transcriptome and its regulation through single-cell multi-omics technologies
Published 2020“…Integrative analysis of multi-omics datasets unravels the relationships between cellular modalities, builds sophisticated regulatory networks, and provides a holistic view of the cell state. …”
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Journal Article